7 completed, 3 unknown, 2 not yet recruiting, 1 suspended. 3 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Suspended 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Acute Brain Injuries: new trials by email Literature Review of Acute Brain Injuries trials Research Report on Acute Brain Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Recombinant Human Growth Hormone in Elderly Patients With Moderate to Severe Acute Brain Injury (GH-ABI-RCT) Recombinant Human Growth Hormone (rhGH) Injection, Standard Care (Treatment as Usual) - Acute Brain Injuries, Moderate to Severe Traumatic Brain Injury | Phase 4 | Not yet recruiting | Anhui Provincial Hospital | 160 | 2026-04-10 | 2026-03-19 |
| PK/PD Target Attainment of Ceftriaxone for the Prevention of Early Ventilator-associated Pneumonia in Neurologically Injured Patients Early Ventilator Associated Pneumonia, Acute Brain Injuries | Not yet recruiting | Central Hospital, Nancy, France | 60 | 2026-03-01 | 2026-03-04 | |
| Building Resiliency in Patients Admitted to the Neuroscience Intensive Care Unit and Their Caregivers Recovering Together - Acute Brain Injuries | Not applicable | Completed | Massachusetts General Hospital | 126 | 2019-01-01 | 2025-05-28 |
| Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury Acute Brain Injuries, Mechanical Ventilation | Withdrawn | Southeast University, China | 2018-01-01 | 2026-06-08 | ||
| CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG Acute Brain Injuries, Consciousness Disorders | Unknown | Copenhagen University Hospital, Rigshospitalet | 100 | 2017-04-12 | 2023-11-15 | |
| A Multidimensional Inpatient Balance Training Class to Improve Functional Outcomes in Rehabilitation Inpatients With ABI Control Balance Training (BT) class, Fallproof Balance Training (BT) class - Brain Injuries, Traumatic, Cerebrovascular Trauma | Not applicable | Unknown | University of British Columbia | 20 | 2017-04-10 | 2017-04-12 |
| Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury gammaCore active device, gammaCore sham device - Traumatic Brain Injury, Acute Brain Injuries | Phase 1 | Completed | CentraCare | 14 | 2016-10-01 | 2021-02-04 |
| Effect of Increased Positive End-expiratory Pressure on Intracranial Pressure in Different Respiratory Mechanic in Acute Respiratory Distress Syndrome Positive end-expiratory pressure - Acute Brain Injuries | Completed | Capital Medical University | 30 | 2016-01-01 | 2017-03-28 | |
| Automated Measurement of Optic Nerve Sheath Diameter Optic nerve ultrasound - Traumatic Brain Injury, Acute Brain Injuries | Completed | University of Michigan | 75 | 2015-07-01 | 2020-12-04 | |
| The Ketogenic Diet for Pediatric Acute Brain Injury Ketogenic diet - Acute Brain Injuries | Not applicable | Suspended | University of California, Los Angeles | 5 | 2015-01-01 | 2025-12-19 |
| Dexmedetomidine-based Sedation in Neurocritical Care Patients Dexmedetomidine - Acute Brain Injuries | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 66 | 2014-04-01 | 2014-09-30 |
| Study of Cerebral Tissue Oxygenation During Transfusion in Traumatic Brain Injury TBI (Traumatic Brain Injury), Acute Brain Injuries | Completed | Unity Health Toronto | 20 | 2012-11-01 | 2015-12-03 | |
| Risk Factors and Outcomes in Patients Treated in Neurocritical Care Observational study, participants are not assigned an intervention as part of the study., Transport modality - Neuro-intensive Care Unit Patients, Subarachnoid Hemorrhage, Aneurysmal | Completed | Karolinska Institutet | 70000 | 2010-01-01 | 2025-07-10 | |
| Dynamic and Static Autoregulation After Brain Injury There are no interventions in this study - Acute Brain Injuries, TBI (Traumatic Brain Injury) | Completed | Johannes Gutenberg University Mainz | 16 | 2001-08-01 | 2013-08-22 |
Brain Injuries (14) · Brain Injuries, Traumatic (7) · Stroke (2) · Cerebral Hemorrhage (1) · Cerebrovascular Trauma (1) · Consciousness Disorders (1) · Epilepsy (1) · Hypoproteinemia (1) · Hypoxia-Ischemia, Brain (1) · Intracranial Hemorrhages (1) · Intracranial Hypertension (1) · Ischemic Stroke (1) · Locked-In Syndrome (1) · Meningitis (1) · Persistent Vegetative State (1)
Brain Diseases (14) · Central Nervous System Diseases (14) · Craniocerebral Trauma (14) · Nervous System Diseases (14) · Trauma, Nervous System (14) · Wounds and Injuries (14) · Cardiovascular Diseases (4) · Cerebrovascular Disorders (4) · Pathological Conditions, Signs and Symptoms (4) · Vascular Diseases (4) · Pathologic Processes (3) · Hemorrhage (2) · Blood Protein Disorders (1) · Brain Damage, Chronic (1) · Brain Ischemia (1)
Artifacts (1) · Dexmedetomidine (1) · Diet, Ketogenic (1) · Growth Hormone (1) · Observation (1) · Positive-Pressure Respiration (1) · Standard of Care (1) · Therapeutics (1)
Anhui Provincial Hospital (1) · Capital Medical University (1) · CentraCare (1) · Central Hospital, Nancy, France (1) · Copenhagen University Hospital, Rigshospitalet (1) · Johannes Gutenberg University Mainz (1) · Karolinska Institutet (1) · Massachusetts General Hospital (1) · Southeast University, China (1) · Unity Health Toronto (1) · University Hospital, Clermont-Ferrand (1) · University of British Columbia (1) · University of California, Los Angeles (1) · University of Michigan (1)
United States (4) · Canada (2) · China (2) · France (2) · Denmark (1) · Germany (1) · Sweden (1)
Ana-Maria Vranceanu, PhD (1) · Andrew Baker, MD (1) · Daniel Kondziella, MD PhD FEBN (1) · Hao Xu (1) · Linn Hallqvist, MD, PhD (1) · Marian Cayer, BSc (1) · Thomas Bergman, MD (1) · Uzma Samadani, MD, PhD (1) · Victoria A McCredie, MBChB (1)
PMID 21252706, PMID 27852713, PMID 30542319, PMID 33052404, PMID 34498896, PMID 36097353, PMID 36869208, PMID 37697124