24 completed, 7 not yet recruiting, 6 unknown, 4 terminated. 10 Not applicable, 9 Phase 4, 8 Phase 3, 2 Phase 1, 1 Phase 2.
Follow Hypoproteinemia: new trials by email Literature Review of Hypoproteinemia trials Research Report on Hypoproteinemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Albumin Therapy in Mechanically Ventilated Patients With Sepsis-Associated ARDS Acute Respiratory Distress Syndrome, Sepsis | Not yet recruiting | The Second Affiliated Hospital of Hainan Medical University | 260 | 2026-10-10 | 2026-10-13 | |
| A Phase I Clinical Study on the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Characteristics of GLR1075 Injection in Healthy Trial Participants and Cirrhotic Trial Participants With Ascites and Hypoalbuminemia placebo GLR1075 Vehicle, Human Serum Albumin(HSA), GLR1075 Injection - Hypoalbuminemia in Cirrhotic Ascites | Phase 1 | Not yet recruiting | Gan & Lee Pharmaceuticals. | 106 | 2026-10-07 | 2026-10-01 |
| Effects of Recombinant Human Growth Hormone in Elderly Patients With Moderate to Severe Acute Brain Injury (GH-ABI-RCT) Recombinant Human Growth Hormone (rhGH) Injection, Standard Care (Treatment as Usual) - Acute Brain Injuries, Moderate to Severe Traumatic Brain Injury | Phase 4 | Not yet recruiting | Anhui Provincial Hospital | 160 | 2026-04-10 | 2026-03-19 |
| Evaluate Recombinant Human Serum Albumin From Oryza Sativa In Patients With Hypoalbuminemia and/or Hypovolemia Requiring Urgent Treatment Recombinant Human Serum Albumin From Oryza Sativa - Hypoalbuminemia, Hypovolemia | Not yet recruiting | Healthgen Biotechnology Corp. | 2000 | 2026-02-24 | 2026-03-02 | |
| Edoxaban Steady-State PK/PD in Adults With Nephrotic Syndrome Edoxaban 60 mg, Enoxaparin 40 mg - Nephrotic Syndrome, Hypoalbuminemia | Not applicable | Not yet recruiting | Peking University People's Hospital | 60 | 2025-09-01 | 2025-08-11 |
| Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke. Dietary Supplement - Stroke, Hypoalbuminemia | Not applicable | Not yet recruiting | University of Ioannina | 100 | 2025-05-05 | 2025-05-08 |
| Silent Threat: Impact of Preoperative Albumin Levels on Outcomes in Geriatric Cancer Surgery Neoplasms, Aged | Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 330 | 2025-04-01 | 2026-04-30 | |
| Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics Study Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant | Not yet recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 350 | 2025-02-15 | 2025-01-30 | |
| I-FALMIN Albumin Supplement for Patients With Pulmonary Tuberculosis Investigational Drug, Placebo - Pulmonary Tuberculosis, Hypoalbuminemia | Not applicable | Active not recruiting | Hasanuddin University | 112 | 2024-12-17 | 2025-09-22 |
| Hypoalbuminemia in Critically Sick Children blood sampling - Hypoalbuminemia | Unknown | Assiut University | 110 | 2024-09-15 | 2024-08-26 | |
| Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia ciprofol - Hypoproteinemia, Pharmacokinetics | Phase 4 | Completed | Xie Kangjie | 36 | 2024-04-04 | 2025-10-01 |
| 90Y Transarterial Radioembolization Versus Microwave Ablation in Small Hepatocellular Carcinoma With Hypoalbuminemia Therasphere 90Y, Microwave Ablation - Carcinoma, Hepatocellular | Not applicable | Recruiting | Ochsner Health System | 50 | 2023-08-08 | 2025-08-03 |
| Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study) Pleural Effusion, Heart Failure | Completed | Chinese University of Hong Kong | 160 | 2023-07-01 | 2026-10-06 | |
| A Study to Evaluate the Efficacy and Safety of OsrHSA in Patients of Hepatic Cirrhosis With Hypoalbuminemia OsrHSA, Plasbumin®-20 - Hypoalbuminemia, Hepatic Cirrhosis | Phase 3 | Completed | Healthgen Biotechnology Corp. | 328 | 2023-04-10 | 2024-04-09 |
| PROGNOSTIC ROLE OF SERUM ALBUMIN LEVEL IN RADIOLOGICAL PROGRESSION OF GONARTHROSIS: IS IT A BIOMARKER IN ITSELF? A BIOMARKER ASSOCIATED WITH SYSTEMIC INFLAMMATION? serum albumin level - Gonarthrosis, Serum Albumin Low | Completed | Ufuk University | 375 | 2023-02-01 | 2023-12-07 | |
| Efficacy of 20% Human Albumin in Reducing Pleural Effusion After Cardiopulmonary Bypass Adding 100ml of 20% human albumin to cardiopulmonary bypass priming solution - Pleural Effusions Post Coronary Artery Bypass Graft, Hypoxia | Phase 4 | Completed | Pauls Stradins Clinical University Hospital | 70 | 2022-09-01 | 2024-11-08 |
| Predicting Worsening Acute Kidney Injury With a Water-Pill (Furosemide) Test and Blood Markers in Patients With Low Albumin Furosemide Stress Test, Serum Biomarkers and NGAL - Acute Kidney Injury, Hypoalbuminemia | Not applicable | Completed | Maithe Caroline Inacio | 55 | 2022-06-04 | 2026-07-07 |
| Nutritional Parameters and Other Risk Factors Affecting Severity of Pneumonia in Children Under Five Years in Upper Egypt Measurement of nutritional parameters in children with pneumonia - Hypoalbuminemia, Stunted Growth | Unknown | Assiut University | 30 | 2021-09-30 | 2021-09-21 | |
| Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome Dalteparin, Apixaban - Nephrotic Syndrome, Thromboembolic Disease | Phase 1 / Phase 2 | Completed | University of Aarhus | 57 | 2021-03-25 | 2025-04-11 |
| Rheumatoid Arthritis Hematological Indices Blood and serum samples - Rheumatoid Arthritis, Serum Albumin Low | Unknown | Assiut University | 40 | 2020-03-01 | 2020-06-04 |
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Hypoalbuminemia (40) · Malnutrition (5) · Critical Illness (3) · Edema (3) · Inflammation (3) · Kidney Failure, Chronic (3) · Nephrotic Syndrome (3) · Acute Kidney Injury (2) · Carcinoma, Hepatocellular (2) · Fibrosis (2) · Glomerulonephritis (2) · Heart Failure (2) · Hyperphosphatemia (2) · Neoplasms (2)
Blood Protein Disorders (44) · Hematologic Diseases (44) · Hemic and Lymphatic Diseases (44) · Pathological Conditions, Signs and Symptoms (24) · Pathologic Processes (21) · Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Male Urogenital Diseases (11) · Urogenital Diseases (11) · Urologic Diseases (11) · Kidney Diseases (10) · Nutritional and Metabolic Diseases (10) · Disease Attributes (8) · Renal Insufficiency (7)
Serum Albumin, Human (4) · Albumins (3) · Blood Specimen Collection (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Crystalloid Solutions (1) · Dalteparin (1) · Dietary Supplements (1) · Drugs, Investigational (1) · Enoxaparin (1) · Growth Hormone (1) · Omeprazole (1) · Pentoxifylline (1) · Saline Solution (1) · Serum Albumin (1) · Sodium Chloride (1)
Assiut University (3) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (2) · Healthgen Biotechnology Corp. (2) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (2) · Akron Children's Hospital (1) · Anhui Provincial Hospital (1) · Ankara University (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Chinese University of Hong Kong (1) · Daxor Corporation (1) · Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital (1) · Erzincan University (1) · Federal University of Mato Grosso (1) · Gan & Lee Pharmaceuticals. (1)
United States (8) · China (7) · France (3) · Turkey (Türkiye) (3) · Canada (2) · Belgium (1) · Brazil (1) · Denmark (1) · Egypt (1) · Germany (1) · Greece (1) · Hong Kong (1) · Indonesia (1) · Italy (1) · Latvia (1)
Alexander Rombauts (1) · Antonio Pesenti, MD (1) · Arezu Dezfuli, MD (1) · Ari Cohen, MD (1) · Avraam Ploumis (1) · Brigitte Schiller-Moran, MD (1) · Eva Strike, MD, PhD (1) · Fatma Meligy, Dr (1) · George A Kaysen, MD Ph.D (1) · Gianni Tognoni, MD (1) · Giovanni Montini, Doctor of Medicine (1) · Hao Xu (1) · Hsiu-Chi Cheng, MD, PhD (1) · Isabel Spriet, PhD PharmD (1)
PMID 20633946, PMID 20699241, PMID 24635772, PMID 24919684, PMID 25018918, PMID 26671516, PMID 26847922, PMID 27495094, PMID 28411114, PMID 28451785, PMID 28474996, PMID 29787743, PMID 29908852, PMID 30261898, PMID 31819422, PMID 32390133, PMID 32409206, PMID 32585739, PMID 32811539, PMID 32819439, PMID 33741039, PMID 34825972, PMID 35810296, PMID 37916745, PMID 40478760, PMID 41333097, PMID 41840567
2016 (1), 2018 (1), R01DK099289 (1), R21DK078012 (1)