82 completed, 35 unknown, 13 recruiting, 11 terminated. 47 Not applicable, 22 Phase 3, 15 Phase 2, 12 Phase 4, 5 Phase 1.
Follow Ventilator Associated Pneumonia: new trials by email Literature Review of Ventilator Associated Pneumonia trials Research Report on Ventilator Associated Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily - Intubation Complication, Stroke, Ischemic | Phase 4 | Not yet recruiting | Hospital San Carlos, Madrid | 60 | 2026-09-15 | 2026-08-06 |
| Probiotic Role in Prevention of Ventilator Associated Pneumonia in Critically- Ill Children Admitted at Pediatric Intensive Care Unit Probiotics, Standard management - Probiotic, Ventilator Associated Pneumonia | Not applicable | Recruiting | Tanta University | 68 | 2026-07-01 | 2026-09-29 |
| Optimizing Enteral Nutrition Regimen for Critically Ill Patients 20-Hour Cycled Enteral Nutrition with a 4-Hour Fasting Window, 18-Hour Cycled Enteral Nutrition with a 6-Hour Fasting Window - Critical Illness, Enteral Nutrition | Not applicable | Not yet recruiting | Hamad Medical Corporation | 150 | 2025-12-30 | 2025-12-08 |
| Effect of a Constructivist Educational Program on Preventing Ventilator-Associated Pneumonia in Intensive Care Units Contructivist, Routine training - Ventilator Associated Pneumonia | Not applicable | Completed | Karaman Training and Research Hospital | 51 | 2025-08-15 | 2026-09-14 |
| Role of Lactoferrin in Prevention of Ventilator Associated Pneumonia in Neonates. Lactoferrin in prevention of VAP, Control - Ventilator Associated Pneumonia | Not applicable | Recruiting | Dalia Mohamed Salah | 120 | 2025-08-01 | 2026-10-06 |
| Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens Multiplex PCR - Ventilator Associated Pneumonia | Not applicable | Recruiting | CHU de Reims | 265 | 2025-03-06 | 2026-09-03 |
| Risk Factors of Ventilator-Associated Pneumonia in Critically Ill Population of Alexandria Ventilator Associated Pneumonia | Completed | Suez Canal University | 180 | 2025-02-20 | 2025-08-11 | |
| Early Severe Illness TrAnslational BioLogy InformaticS in Humans Phelebotomy, Broncheoalveolar Lavage, Tracheal Aspirate - Sepsis, ARDS | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 1000 | 2024-04-26 | 2025-10-06 | |
| Single-used Versus MultiPlE-used Endotracheal suCtIon cAtheters in Mechanically ventiLated ICU Patients Suction Circuit Flushing with Chlorhexidine - Ventilator Associated Pneumonia | Not applicable | Completed | Mansoura University | 60 | 2024-04-15 | 2025-01-03 |
| MASTERMIND-Pneumonia Study (Also Known as Pneumonia Direct Pilot) Pathogen and Host Directed testing - Pneumonia, Bacterial, Ventilator Associated Pneumonia | Completed | Duke University | 173 | 2024-04-12 | 2026-04-27 | |
| Antibiotic Therapy Practices for Ventilator-Associated Pneumonia (PETUNIA) Antibiotic - Ventilator Associated Pneumonia | Unknown | French Society for Intensive Care | 1060 | 2024-03-12 | 2024-03-15 | |
| M-I/E for Preventing VAP in Post-neurosurgical Patients Ventilator Associated Pneumonia, Brain Injuries | Completed | Beijing Sanbo Brain Hospital | 210 | 2024-03-04 | 2025-03-19 | |
| Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements Intermittent Positive pressure ventilation - Hypoxemia, Hypercapnia | Unknown | University Medical Center Groningen | 20000 | 2024-03-01 | 2024-03-07 | |
| Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL Acyclovir - Pneumonia, Viral, Ventilator Associated Pneumonia | Phase 3 | Recruiting | Jena University Hospital | 616 | 2024-02-20 | 2026-07-23 |
| Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients. Suctioning of artificial airway - Tracheostomy, Endotracheal Tube | Unknown | Northwell Health | 50 | 2023-12-20 | 2024-01-17 | |
| Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT) LactoLevure, Placebo - Ventilator Associated Pneumonia | Not applicable | Completed | University of Bari | 213 | 2023-12-13 | 2026-10-27 |
| EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics Rapid Diagnostics - Blood Stream Infections, Ventilator Associated Pneumonia | Phase 4 | Recruiting | National University of Singapore | 1526 | 2023-12-12 | 2026-10-22 |
| Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit Standardized oral Care - Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia | Not applicable | Recruiting | University of Florida | 218 | 2023-11-23 | 2026-07-08 |
| Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit cotrimoxazole, standard antibiotic therapy - Ventilator Associated Pneumonia | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 628 | 2023-10-19 | 2025-05-20 |
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Pneumonia, Ventilator-Associated (149) · Healthcare-Associated Pneumonia (12) · Pneumonia (11) · COVID-19 (7) · Critical Illness (6) · Cross Infection (6) · Brain Injuries, Traumatic (4) · Infections (4) · Sepsis (4) · Acute Lung Injury (3) · Brain Injuries (3) · Communicable Diseases (3) · Community-Acquired Pneumonia (3) · Pneumonia, Bacterial (3) · Pseudomonas Infections (3)
Disease Attributes (149) · Lung Diseases (149) · Pathologic Processes (149) · Pathological Conditions, Signs and Symptoms (149) · Respiratory Tract Diseases (149) · Iatrogenic Disease (148) · Respiratory Tract Infections (146) · Infections (145) · Cross Infection (143) · Pneumonia (138) · Healthcare-Associated Pneumonia (137) · Bacterial Infections and Mycoses (12) · Bacterial Infections (11) · Virus Diseases (10) · Coronaviridae Infections (8)
Chlorhexidine (5) · Colistin (4) · Saline Solution (4) · Toothbrushing (3) · chlorhexidine gluconate (3) · Bronchoscopy (2) · Imipenem (2) · Povidone-Iodine (2) · Ventilators, Mechanical (2) · Acetylcysteine (1) · Acyclovir (1) · Amikacin (1) · Aminoglycosides (1) · Anidulafungin (1) · Anti-Bacterial Agents (1)
Assiut University (7) · Assistance Publique - Hôpitaux de Paris (3) · Mansoura University (3) · Beijing Chao Yang Hospital (2) · Centre Hospitalier Universitaire de Nīmes (2) · Damanhour University (2) · Fondation Hôpital Saint-Joseph (2) · Hospital Pablo Tobón Uribe (2) · Hospitech Respiration (2) · King Abdul Aziz Specialist Hospital (2) · National Taiwan University Hospital (2) · Semmelweis University (2) · St. Joseph's Hospital and Medical Center, Phoenix (2) · University Hospital, Lille (2) · University of Florida (2)
United States (22) · France (19) · Canada (10) · Egypt (10) · Spain (9) · Greece (8) · Italy (8) · Turkey (Türkiye) (8) · India (6) · Malaysia (5) · United Kingdom (5) · Brazil (4) · China (4) · Israel (4) · Romania (4)
Daren Heyland, MD (2) · Aaron Milstone, MD, MHS (1) · Adi Osman, MD (1) · Alberto Corriero, MD (1) · Aleks Leligdowicz, MD PhD (1) · Alessandra Bandera, MD, PhD (1) · Alexandre B Cavalcanti, M.D (1) · Amal M Hosni, lecturer (1) · Andrea Gori, MD (1) · Anil Sachdev, MD (1) · Anthony Gordon, MD FRCA (1) · Antoni Torres, MD PhD (1) · Apostolos Armaganidis, MD, PhD (1)
PMID 17872488, PMID 10816031, PMID 11778260, PMID 11888973, PMID 11934711, PMID 15447947, PMID 17994522, PMID 18421435, PMID 18641114, PMID 18707849, PMID 18951395, PMID 19237884, PMID 20125046, PMID 20522788, PMID 20584505, PMID 20936977, PMID 21129208, PMID 21249529, PMID 21287306, PMID 21312329, PMID 21418551, PMID 21478738, PMID 21558772, PMID 21740312, PMID 21839732, PMID 22186217, PMID 22258968, PMID 22422274, PMID 22497915, PMID 22760426, PMID 23222254, PMID 23352693, PMID 23583261, PMID 23622939, PMID 23727136, PMID 24105456, PMID 24162674, PMID 24207137, PMID 24393424, PMID 24903189, PMID 24969718, PMID 24981955, PMID 25050644, PMID 25319385, PMID 25327505, PMID 25343570, PMID 26030716, PMID 26205553, PMID 26357898, PMID 26377207
2017 (1), 2025 (1), 5UM1AI104681 (1), K24AI141580 (1), R01NR007652 (1), R43HL131177 (1), R56DE034473 (1)