34 completed, 6 unknown, 3 not yet recruiting, 2 recruiting. 31 Not applicable, 6 Phase 2, 3 Phase 1, 2 Early Phase 1, 2 Phase 3.
Follow Toothbrushing: new trials by email Literature Review of Toothbrushing trials Research Report on Toothbrushing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Changes in Matrix Metalloproteinase-9 Levels With Salvadora Persica (Miswak) in Periodontal Fibroblasts and Gingival Crevicular Fluid in Patients With Periodontitis Salvadora Persica Root, Toothbrushing - Stage II or Stage III Grade B Periodontitis | Early Phase 1 | Not yet recruiting | Cairo University | 24 | 2026-06-01 | 2026-05-20 |
| Non-invasive Characterisation of Oral Carcinomas in Patients With Fanconi Anaemia Oral brushing - Fanconi Anaemia | Not applicable | Not yet recruiting | Institut Jean-Godinot | 115 | 2026-04-01 | 2025-11-21 |
| Effect of Water Flossing on Gingival Inflammation Around Single Implants Water flosser, Tooth brush and string floss - Peri Implant Mucositis | Not applicable | Not yet recruiting | King Abdulaziz University | 20 | 2026-01-01 | 2026-01-23 |
| Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial Tooth Brushing Alone (Control), Water flosser, Interproximal Brush - Gingivitis, Dental Plaque | Not applicable | Completed | Saint-Joseph University | 29 | 2025-10-28 | 2026-07-28 |
| Determination of the Oral Irritation Potential of a Fluoride Rinse in Children Brush Only, Brush / Rinse (Jolly Rancher Prototype), Brush / Rinse (LISTERINE® Total Care Zero Alcohol) - Healthy | Not applicable | Completed | Johnson & Johnson Consumer and Personal Products Worldwide | 161 | 2025-01-20 | 2025-03-12 |
| Efficacy of an Amine and Zinc Lactate - Containing Mouthrinse in the Home-based Treatment of Plaque-induced Gingivitis in Adolescents. toothbrushing, flossing, Toothpaste Product - Gingivitis | Not applicable | Recruiting | Università degli Studi di Ferrara | 150 | 2025-01-07 | 2025-03-25 |
| Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss Brushing and Flossing of teeth, Brushing Only - Gingivitis, Supragingival Plaque | Not applicable | Completed | Indiana University | 64 | 2024-10-15 | 2025-06-13 |
| Comparative Analysis of Interventions for Prevention of Dental Caries in School Children Tooth brushing, tooth paste containing 1450ppm fluoride - Prevention of Dental Caries | Not applicable | Active not recruiting | Bahria University | 180 | 2024-10-05 | 2025-09-23 |
| Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash Brush / Espresso Mild Prototype, Brush / Espresso Intense Prototype, Brush / Fresh Breath Oral Rinse - Oral Malodor | Not applicable | Completed | Johnson & Johnson Consumer and Personal Products Worldwide | 166 | 2024-07-15 | 2025-01-08 |
| Impact of Oral Care on Ventilator Associated Pneumonia Toothbrushing + Chlorhexidine, Routine oral care + Chlorohexidine - Ventilator Associated Pneumonia ( VAP) | Not applicable | Completed | Ain Shams University | 118 | 2024-06-15 | 2025-12-17 |
| Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous - Periodontitis, Gingivitis | Not applicable | Recruiting | Missouri Department of Health and Senior Services | 150 | 2024-03-01 | 2025-03-26 |
| The Effects of Different Tooth Brushing Explanations in Fixed Orthodontic Treatment Tooth brushing - Orthodontic Treatment, Dental Plaque Induced Gingival Disease | Not applicable | Completed | Yuzuncu Yil University | 80 | 2024-01-15 | 2024-07-31 |
| Plaque Removal by Triple-Headed Manual Toothbrush Toothbrushing with triple-headed manual toothbrush, Toothbrushing with standard manual toothbrush - Plaque, Dental | Not applicable | Completed | Ataturk University | 48 | 2024-01-01 | 2025-01-28 |
| Effectiveness of Different Types of Toothbrushes on Periodontal Health in Orthodontic Patients Toothbrushing - Gingivitis, Orthodontics | Not applicable | Completed | Okan University | 36 | 2023-08-01 | 2024-07-19 |
| Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction Brushing - Caries, Gingivitis | Not applicable | Completed | University of Bologna | 100 | 2022-12-01 | 2025-04-29 |
| Bronchial Washing Beforeand After Endobronchial Biopsy and Bronchial Brushing Bronchial washing before endobronchial biopsy and brushing - Lung Cancer | Not applicable | Completed | Chinese University of Hong Kong | 118 | 2022-10-01 | 2024-08-20 |
| Toothbrushing Program in Saudi Arabia "TOPS" Supervised Toothbrushing - Dental Caries in Children | Not applicable | Completed | University of Glasgow | 588 | 2022-09-18 | 2025-04-27 |
| The Effects of Ankaferd Blood Stopper Ankaferd Blood Stopper, Bicarbonate - Colon Cancer, Oral Mucositis | Not applicable | Unknown | Uludag University | 66 | 2021-06-01 | 2023-06-01 |
| Efficacy of Different Toothbrushes and Hygiene Regimen Total 12 regimen, Toothbrushing alone - Dental Plaque, Halitosis | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 58 | 2021-01-05 | 2020-09-21 |
| PROSAIC-19 - Prospective Longitudinal Assessment in a COVID-19 Infected Cohort Blood tests sputum, nasal lavage and brushing - COVID-19, SARS-CoV 2 | Completed | Imperial College London | 161 | 2020-06-18 | 2026-07-02 |
Showing 20 of 47. Sign in to see all of them.
Gingivitis (8) · Dental Plaque (7) · Pneumonia, Ventilator-Associated (7) · Dental Caries (5) · Pneumonia (4) · Mucositis (3) · Periodontal Diseases (3) · Chronic Periodontitis (2) · Gingival Recession (2) · Anus Neoplasms (1) · COVID-19 (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Cross Infection (1) · Cystinosis (1)
Cairo University (2) · Federal University of São Paulo (2) · Government College of Dentistry, Indore (2) · Johnson & Johnson Consumer and Personal Products Worldwide (2) · A.T. Still University of Health Sciences (1) · Ain Shams University (1) · Ataturk University (1) · Azad University of Medical Sciences (1) · Bahria University (1) · Chinese University of Hong Kong (1) · CytoCore, Inc. (1) · Dokuz Eylul University (1) · Franciscan University Center (1) · Heba sabbagh (1) · Hospital Universitari Joan XXIII de Tarragona. (1)
United States (12) · Turkey (Türkiye) (5) · Egypt (3) · Spain (3) · Brazil (2) · Italy (2) · Chile (1) · France (1) · Hong Kong (1) · Iran (1) · Lebanon (1) · Norway (1) · Pakistan (1) · Saudi Arabia (1) · United Kingdom (1)
Dr Subhash Garg, MDS (2) · Ahmed R. Ahmed, MD (1) · Amal G Jamjoom (1) · Amy McMIchael, MD (1) · Ana G Gossweiler, DDS/MSD (1) · Ashley C Grill, MPH, RDH (1) · Bente Kristensen, BSc (1) · Cindy Munro, RN, ANP,PhD (1) · David SC Hui, MD (1) · Frederick A Curro, DMD, PhD (1)
PMID 3509967, PMID 11686809, PMID 15312097, PMID 16041502, PMID 16849078, PMID 17022370, PMID 18304416, PMID 19138181, PMID 19482956, PMID 21811688, PMID 22422274, PMID 22497915, PMID 24854326, PMID 25079400, PMID 25091189, PMID 25596649, PMID 27681016, PMID 27891568, PMID 280130, PMID 28143414, PMID 29189950, PMID 31176788, PMID 31286226, PMID 31631858, PMID 32054468, PMID 32951930, PMID 37289263, PMID 38997790, PMID 39097315, PMID 39455996, PMID 39572408, PMID 42502162, PMID 4500561, PMID 9659518
R01NR007652 (1)