25 completed, 6 terminated, 1 unknown, 1 withdrawn. 11 Phase 3, 9 Phase 2, 9 Phase 4, 3 Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 7, Terminated 3, Withdrawn 1 |
| Phase 2 | 9 | Completed 6, Terminated 2, Unknown 1 |
| Phase 4 | 9 | Completed 8, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Not applicable | 1 | Completed 1 |
Follow Anidulafungin: new trials by email Literature Review of Anidulafungin trials Research Report on Anidulafungin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole SCY-078, Fluconazole, Echinocandin - Candidiasis, Invasive, Candidemia | Phase 3 | Terminated | Scynexis, Inc. | 68 | 2022-08-03 | 2026-08-10 |
| Azole-echinocandin Combination Therapy for Invasive Aspergillosis Azole, Anidulafungin - Invasive Aspergillosis | Phase 3 | Terminated | Erasmus Medical Center | 66 | 2021-05-11 | 2024-05-07 |
| Anidulafungin Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ADOPT) Anidulafungin 100mg single dose iv - Obesity Morbid | Phase 4 | Completed | Radboud University Medical Center | 8 | 2014-08-01 | 2020-12-01 |
| Negative Beta Glucan in ICU Patients Anidulafungin - Candidemia | Phase 4 | Completed | Universidade Federal do Rio de Janeiro | 85 | 2012-11-01 | 2019-07-08 |
| Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents Parenteral micafungin application, Other parenteral antifungal drugs - Systemic Fungal Infections | Completed | Astellas Pharma Europe B.V. | 40110 | 2012-10-01 | 2024-10-21 | |
| Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects Voriconazole, Anidulafungin - Aspergillosis, Invasive Pulmonary Aspergillosis | Phase 3 | Withdrawn | Pfizer | 2012-05-01 | 2012-05-11 | |
| Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant Recipients Anidulafungin, Liposomal amphotericin B - Liver Disease, Fungal Infection | Phase 4 | Completed | Fundacion SEIMC-GESIDA | 61 | 2011-11-01 | 2014-05-30 |
| Early Clinical Experience With Anidulafungin In Patients With Liver Disease In The United Kingdom anidulafungin - Candidiasis | Completed | Pfizer | 50 | 2011-02-01 | 2014-04-16 | |
| Effect of Weight and/or Obesity on Anidulafungin Drug Concentrations Anidulafungin - Obesity, Mycoses | Phase 4 | Completed | Texas Tech University Health Sciences Center | 20 | 2011-01-01 | 2019-01-09 |
| A Study Of The Efficacy And Safety Of Anidulafungin Vs. Fluconazole In The Treatment Of Patients With Candidemia And/Or Other Forms Of Invasive Candidiasis Anidulafungin/Fluconazole - Candidemia | Phase 3 | Terminated | Pfizer | 17 | 2010-12-01 | 2015-10-28 |
| Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease anidulafungin 200 mg q48h, anidulafungin 300 mg q72h - Leukemia, Myelodysplastic Syndrome | Phase 2 | Completed | Radboud University Medical Center | 26 | 2010-11-01 | 2020-12-08 |
| Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment Normal Saline, anidulafungin - Ventilator Associated Pneumonia, Respiratory Tract Infection | Phase 2 | Terminated | Daren K. Heyland | 61 | 2010-04-01 | 2021-02-01 |
| Anidulafungin Versus Fluconazole for the Prevention of Fungal Infections in Liver Transplant Recipients Anidulafungin, Fluconazole - Mycoses, Fungemia | Phase 4 | Completed | University of Pittsburgh | 200 | 2010-02-01 | 2014-12-17 |
| Anidulafungin in Patients With Hematologic Malignancies Anidulafungin - Hematologic Malignancies | Phase 2 | Terminated | Elisabethinen Hospital | 10 | 2009-10-01 | 2012-03-02 |
| Anidulafungin During Continuous Venovenous Hemofiltration (CVVHF) Anidulafungin - Acute Renal Failure, Infection | Phase 2 | Unknown | Medical University of Vienna | 10 | 2009-04-01 | 2009-05-04 |
| Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasis Anidulafungin, Fluconazole - Candidemia | Phase 3 | Completed | Pfizer | 70 | 2009-02-01 | 2019-04-04 |
| A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects anidulafungin and voriconazole - Aspergillosis, Candidemia | Phase 4 | Completed | Pfizer | 24 | 2008-09-01 | 2010-02-09 |
| Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene) voriconazole, anidulafungin - Aspergillosis | Phase 4 | Terminated | Pfizer | 6 | 2008-08-01 | 2010-02-15 |
| Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis voriconazole, anidulafungin - Aspergillosis | Phase 3 | Completed | Pfizer | 459 | 2008-07-01 | 2012-04-30 |
| Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study Anidulafungin, Fluconazole, Voriconazole - Invasive Candidiasis | Phase 3 | Completed | Pfizer | 216 | 2008-07-01 | 2011-05-30 |
Showing 20 of 33. Sign in to see all of them.
Candidemia (13) · Candidiasis, Invasive (9) · Candidiasis (6) · Aspergillosis (5) · Mycoses (5) · Torulopsis (4) · Infections (3) · Invasive Fungal Infections (2) · Neutropenia (2) · Systemic candidiasis (2) · Acute Kidney Injury (1) · Carcinoma, Hepatocellular (1) · Central Nervous System Fungal Infections (1) · Febrile Neutropenia (1) · Fever (1)
Pfizer (16) · Duke University (2) · National Cancer Institute (NCI) (2) · Radboud University Medical Center (2) · Astellas Pharma Europe B.V. (1) · Daren K. Heyland (1) · Elisabethinen Hospital (1) · Erasmus Medical Center (1) · Fundacion SEIMC-GESIDA (1) · Medical University of Vienna (1) · Michael Cohen-Wolkowiez (1) · Scynexis, Inc. (1) · Texas Tech University Health Sciences Center (1) · Universidade Federal do Rio de Janeiro (1) · University of Pittsburgh (1)
United States (19) · Canada (5) · Netherlands (5) · Belgium (4) · Brazil (4) · Greece (4) · Italy (4) · South Korea (4) · Spain (4) · United Kingdom (4) · Austria (3) · France (3) · Germany (3) · Russia (3) · Taiwan (3)
Asuncion Moreno, MD (1) · Barbara D Alexander, MD (1) · Bart Rijnders, MD, PhD (1) · Carlos Cervera, MD (1) · Danny Benjamin, MD (1) · Daren Heyland, MD (1) · David Angulo, MD (1) · John Perfect, MD (1) · Kimberly E Hanson, MD (1) · Marcio Nucci, MD (1) · Mary Jayne Kennedy, Pharm, D (1) · Michael Girschikofsky, MD (1)
PMID 28459966, PMID 28597967, PMID 31280481, PMID 33891293, PMID 17568028, PMID 21287306, PMID 21961941, PMID 22026929, PMID 22879929, PMID 23676114, PMID 23710653, PMID 24559321, PMID 24913161, PMID 24914120, PMID 24981955, PMID 25376267, PMID 25473029, PMID 25599346, PMID 26050015, PMID 27142114, PMID 27287231, PMID 30418357, PMID 32032174, PMID 39378343
2008 (1), 2009 (1), 5UL1RR024982-02 (1)