128 completed, 32 unknown, 13 terminated, 12 recruiting. 47 Not applicable, 35 Phase 3, 27 Phase 2, 24 Phase 4, 21 Phase 1.
Follow Pneumonia, Bacterial: new trials by email Literature Review of Pneumonia, Bacterial trials Research Report on Pneumonia, Bacterial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose Primary Dosing Series Followed by a Booster Dose at 12 to 15 Months of Age Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Not yet recruiting | GlaxoSmithKline | 60 | 2027-01-25 | 2026-07-16 |
| Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care Center Tonsillitis Acute, Pneumonia - Bacterial | Not yet recruiting | University Hospital, Montpellier | 191 | 2026-09-01 | 2026-07-17 | |
| Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic Therapy Machine Learning Decision Support System - Pneumonia - Bacterial, Urinary Tract Infection Bacterial | Not applicable | Not yet recruiting | Instituto de Investigación Sanitaria Gregorio Marañón | 486 | 2026-09-01 | 2026-08-13 |
| Urine Pneumococcal Antigen Project Pneumonia, Pneumonia - Bacterial | Recruiting | Liverpool School of Tropical Medicine | 350 | 2026-09-01 | 2026-09-10 | |
| " Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation " Amikacin, Standard of care - Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 26 | 2026-08-10 | 2026-08-13 |
| MP101 in Adults With Acute Pseudomonas Aeruginosa Pneumonia MP101, Antibiotics - Pneumonia - Bacterial, Pseudomonas Aeruginosa Infection | Phase 1 | Recruiting | MicrobiotiX Co., Ltd | 18 | 2026-07-25 | 2026-07-28 |
| Community-acquired Pneumonia Due to Chlamydia Pneumoniae Community-Acquired Pneumonia | Not yet recruiting | Centre Hospitalier de Saint-Denis | 200 | 2026-06-01 | 2026-07-01 | |
| Impact of BioFire FilmArray Pneumonia Panel vs Routine Diagnostics on Antimicrobial Outcomes (DOOR-MAT) Multiplex PCR-based pneumonia panel (BIOFIRE® FILMARRAY® Pneumonia Panel) - Pneumonia - Bacterial | Not applicable | Recruiting | Hospital de Clinicas de Porto Alegre | 150 | 2026-05-20 | 2026-09-17 |
| A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months of Age Receiving a Single Booster Dose Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Active not recruiting | GlaxoSmithKline | 46 | 2026-05-15 | 2026-09-28 |
| Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Active not recruiting | GlaxoSmithKline | 121 | 2026-03-10 | 2026-05-27 |
| Combination vs. Monotherapy for Stenotrophomonas Maltophilia Infections Bloodstream Infection, Pneumonia - Bacterial | Completed | Instituto de Investigación Sanitaria Gregorio Marañón | 1718 | 2026-03-06 | 2026-10-13 | |
| Artificial Intelligence-Based Evaluation of Chest X-Rays in Ventilator-Associated Pneumonia Ventilator-Associated Pneumonia, Intensive Care Unit (ICU) | Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 119 | 2026-03-01 | 2026-04-03 | |
| Doxycycline vs. Macrolide for MRMP (DOMINO) Doxycycline, Azithromycin - Mycoplasma Pneumoniae, Mycoplasma Pneumoniae Pneumonia | Phase 4 | Not yet recruiting | Young June Choe | 208 | 2026-03-01 | 2025-12-29 |
| Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases - OXIGENE - Characterization of the neutrophil granulocyte epigenome, Characterization of the T-cell immune response to to various oxidatively modified mycobacterial antigens - Asthma, COPD | Not yet recruiting | Research Center Borstel | 100 | 2026-02-01 | 2026-02-04 | |
| A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection Bacteremia Caused by Gram-Negative Bacteria, Bacterial Pneumonia | Recruiting | TTY Biopharm | 480 | 2025-11-26 | 2026-03-09 | |
| A Trial to Evaluate the Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults 50 To 64 Years of Age Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Completed | GlaxoSmithKline | 127 | 2025-08-12 | 2026-06-05 |
| Antimicrobial Therapeutic Drug Monitoring During Lung Transplant Perioperative Phase Lung Transplant Infection, Pneumonia, Bacterial | Not yet recruiting | Policlinico Hospital | 20 | 2025-07-01 | 2025-05-22 | |
| Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABP Cefepime-taniborbactam, Meropenem - Ventilator-associated Pneumonia, Hospital-acquired Pneumonia | Phase 3 | Withdrawn | Venatorx Pharmaceuticals, Inc. | 2025-06-01 | 2025-06-08 | |
| Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP Lung ultrasound, Standard of Care (SOC) - Pneumonia, Pneumonia Childhood | Not applicable | Recruiting | Ecole Polytechnique Fédérale de Lausanne | 4894 | 2025-04-04 | 2026-10-05 |
| Efficacy and Safety of Faropenem in Bangladeshi Adult Patients With Community-Acquired Bacterial Pneumonia (CABP) Faropenem, Co-amoxiclav, Clarithromycin 500 mg - Pneumonia, Community-Acquired, Bacterial Pneumonia | Phase 4 | Completed | Dr. Md. Alimur Reza | 129 | 2025-02-20 | 2026-08-04 |
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Pneumonia (46) · Pneumonia, Pneumococcal (44) · Community-Acquired Pneumonia (25) · Pneumonia, Mycoplasma (20) · Pneumonia, Ventilator-Associated (17) · Pneumococcal Infections (14) · Pneumonia, Viral (14) · Bacterial Infections (12) · Healthcare-Associated Pneumonia (12) · Respiratory Tract Infections (12) · Influenza, Human (10) · Pneumonia, Staphylococcal (8) · Sepsis (8) · Cross Infection (6)
Bacterial Infections and Mycoses (203) · Infections (199) · Respiratory Tract Diseases (199) · Lung Diseases (197) · Bacterial Infections (191) · Respiratory Tract Infections (191) · Pneumonia (157) · Gram-Positive Bacterial Infections (60) · Pathological Conditions, Signs and Symptoms (50) · Pathologic Processes (49) · Streptococcal Infections (47) · Disease Attributes (35) · Pneumococcal Infections (34) · Virus Diseases (30)
Azithromycin (9) · Levofloxacin (7) · Pneumococcal Vaccines (7) · Ceftriaxone (6) · Vancomycin (6) · 13-valent pneumococcal vaccine (5) · PHiD-CV vaccine (5) · Tigecycline (5) · 23-valent pneumococcal capsular polysaccharide vaccine (4) · Doripenem (4) · Doxycycline (4) · Heptavalent Pneumococcal Conjugate Vaccine (4) · Moxifloxacin (4) · Anti-Bacterial Agents (3) · Blood Specimen Collection (3)
Pfizer (7) · GlaxoSmithKline (6) · Merck Sharp & Dohme LLC (6) · Wyeth is now a wholly owned subsidiary of Pfizer (5) · Massachusetts General Hospital (4) · Assistance Publique - Hôpitaux de Paris (3) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (3) · China National Biotec Group Company Limited (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · PATH (3) · Seoul National University Hospital (3) · Azienda Ospedaliero-Universitaria Careggi (2) · Bayer (2) · Biotest (2) · Boston University (2)
United States (60) · France (26) · Spain (18) · China (16) · Germany (15) · Taiwan (15) · Hungary (12) · Russia (11) · South Korea (11) · Brazil (10) · Italy (10) · Argentina (9) · Poland (9) · South Africa (9) · Turkey (Türkiye) (9)
Patricia L Hibberd, MD, PhD (4) · Du Lin, Master (3) · G. Ralph Corey, MD (2) · Jae-Joon Yim, MD (2) · Jerome J Schentag, Pharm.D. (2) · Joseph Paladino, Pharm.D. (2) · Julio A Ramirez, MD (2) · Abdullah T Aslan, Dr. (1)
PMID 18444848, PMID 18508226, PMID 21482570, PMID 23357290, PMID 24708675, PMID 25487791, PMID 26702925, PMID 27718118, PMID 29454592, PMID 30597021, PMID 34593497, PMID 34922058, PMID 11296335, PMID 11990923, PMID 12802491, PMID 14564379, PMID 14998500, PMID 15917525, PMID 16669925, PMID 17029130, PMID 17901791, PMID 18436554, PMID 18470901, PMID 18990531, PMID 19036672, PMID 19384209, PMID 19740418, PMID 20097417, PMID 20686433, PMID 21030489, PMID 21482566, PMID 21482568, PMID 21936959, PMID 22205782, PMID 22249106, PMID 22302662, PMID 22653088, PMID 22805273, PMID 22812672, PMID 23123106, PMID 23131206, PMID 23153437, PMID 23357775, PMID 23459495, PMID 23882105, PMID 24011955, PMID 24086113, PMID 24102758, PMID 24277028, PMID 24279701
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