58 completed, 19 unknown, 7 terminated, 7 withdrawn. 98 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 98 | Completed 58, Unknown 19, Terminated 7, Withdrawn 7, Recruiting 5, Not yet recruiting 2 |
Follow Uterine Hemorrhage: new trials by email Literature Review of Uterine Hemorrhage trials Research Report on Uterine Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial Carbetocin, Oxytocin, Placebo Saline Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Recruiting | Mansoura University | 332 | 2026-08-08 | 2026-10-09 |
| Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR) Oxytocin Bolus or Oxytocin Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Not yet recruiting | Stony Brook University | 180 | 2026-08-01 | 2026-08-03 |
| Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy Cyclobenzaprine - Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified | Phase 4 | Not yet recruiting | Christiana Care Health Services | 36 | 2026-07-01 | 2026-06-24 |
| Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage Carbetocin, Oxytocin - Postpartum Hemorrhage, Twin Pregnancy | Phase 4 | Recruiting | Sheba Medical Center | 120 | 2026-05-05 | 2026-05-08 |
| A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India Eptacog alfa (NovoSeven) - Severe Postpartum Haemorrhage | Phase 4 | Recruiting | Novo Nordisk A/S | 64 | 2025-08-26 | 2026-09-25 |
| Comparing Intra-Umbilical Versus Intravenous Oxytocin in Women During the Third Stage of Labor for Reducing Blood Loss Oxytocin after delivery, Intraumbilical oxytocin - Postpartum Bleeding, Oxytocin | Phase 4 | Completed | CMH Multan Institute of Medical Sciences | 60 | 2025-08-13 | 2026-05-05 |
| Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome Myo-Inositol and D-Chiro-Inositol Combination Therapy, placebo (folic acid) - Polycystic Ovary Syndrome (PCOS), Myo-inositol | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-06-01 | 2026-07-14 |
| Prophylactic Tranexamic Acid Reduces Postpartum Hemorrhage tranexamic acid, normal saline - Postpartum Hemorrhage, Systemic Autoimmune Diseases | Phase 4 | Recruiting | RenJi Hospital | 276 | 2025-01-06 | 2025-03-17 |
| SWIFT - SWIss Factor XIII Trial in PPH Fibrogammin - Postpartum Hemorrhage, Coagulation Disorder | Phase 4 | Recruiting | Christian Haslinger | 988 | 2024-07-09 | 2026-04-27 |
| TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study Tranexamic acid, No Tranexamic acid - Venous Thromboembolism, Venous Thromboses | Phase 4 | Unknown | University Health Network, Toronto | 20 | 2024-06-01 | 2024-06-12 |
| Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study. Tranexamic Acid (TXA) - Healthy Participants | Phase 4 | Completed | University of British Columbia | 110 | 2024-03-30 | 2026-10-08 |
| Comparison of the Efficacy of Misoprostol and Tranexamic Acid for Postpartum Hemorrhage Prophylaxis in Cesarean Delivery Tranexamic acid, Misoprostol 200mcg Tab - Postpartum Hemorrhage, Cesarean Section Complications | Phase 4 | Completed | Ankara Etlik City Hospital | 192 | 2023-12-01 | 2026-08-06 |
| Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean Section Misoprostol 200mcg Tab, Misoprostol Pill - Misoprostol Allergy | Phase 4 | Unknown | Cairo University | 120 | 2023-06-01 | 2023-08-23 |
| Comparison Of The Effects Of Carbetocin And Oxytocin In C-Sectıon C-sections operations, Oxytocin, Carbetocin - Carbetocin, Oxytocic Drugs Causing Adverse Effects in Therapeutic Use | Phase 4 | Unknown | Ege University | 200 | 2023-03-09 | 2023-03-07 |
| Prophylactic Methylergonovine for Twin Cesarean Methylergonovine, Placebo - Twin; Complicating Pregnancy, Postpartum Hemorrhage | Phase 4 | Completed | Columbia University | 66 | 2023-03-07 | 2025-06-13 |
| Use of Chitosan Powder in Loop Electrosurgical Excision Procedure Chitosan - Vaginal Bleeding, Loop Electrosurgical Excision | Phase 4 | Completed | Erzincan Military Hospital | 130 | 2022-12-15 | 2024-06-26 |
| Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL) Myfembree Oral Product - Metrorrhagia, Pelvic Pain | Phase 4 | Withdrawn | University of Chicago | 2022-11-20 | 2026-06-05 | |
| Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail Tranexamic acid, Placebo - Episiotomy Wound, Anemia | Phase 4 | Completed | Assuta Ashdod Hospital | 150 | 2022-07-25 | 2024-12-05 |
| Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot Trial Tamoxifen Citrate 10Mg Tab, Estradiol, Placebo - Vaginal Bleeding | Phase 4 | Withdrawn | Virginia Commonwealth University | 2022-05-01 | 2022-06-03 | |
| A Trial of Sublingual Misoprostol to Reduce Primary Postpartum Haemorrhage After Vaginal Delivery Misoprostol - Primary Postpartum Hemorrhage, Misoprostol | Phase 4 | Unknown | The University of Hong Kong | 1300 | 2022-04-01 | 2022-03-03 |
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Postpartum Hemorrhage (59) · Menorrhagia (26) · Metrorrhagia (17) · Hemorrhage (10) · Uterine Inertia (10) · Leiomyoma (8) · Hemostatic Disorders (5) · Anemia (4) · Blood Loss, Surgical (4) · Adenomyosis (3) · Agnosia (3) · Pain (3) · Anemia, Iron-Deficiency (2) · Menstruation Disturbances (2)
Female Urogenital Diseases and Pregnancy Complications (98) · Pathologic Processes (98) · Pathological Conditions, Signs and Symptoms (98) · Urogenital Diseases (98) · Hemorrhage (88) · Obstetric Labor Complications (59) · Puerperal Disorders (59) · Pregnancy Complications (58) · Female Urogenital Diseases (39) · Genital Diseases (39) · Genital Diseases, Female (39) · Uterine Diseases (39) · Menstruation Disturbances (24) · Hematologic Diseases (11)
Misoprostol (16) · Tranexamic Acid (16) · carbetocin (16) · Oxytocin (15) · Saline Solution (4) · Sodium Chloride (4) · Estradiol (3) · Levonorgestrel (3) · Tamoxifen (3) · ulipristal acetate (3) · Ethinyl Estradiol-Norgestrel Combination (2) · Folic Acid (2) · Iron (2) · Ketorolac (2) · Ketorolac Tromethamine (2)
Cairo University (5) · Gynuity Health Projects (4) · Assiut University (3) · Beni-Suef University (3) · Oregon Health and Science University (3) · Bayer (2) · Erzincan Military Hospital (2) · Scott and White Hospital & Clinic (2) · Talkha Central Hospital (2) · AbbVie (1) · Abimbola Famuyide (1) · Ain Shams Maternity Hospital (1) · Al-Kindy College of Medicine (1) · Ankara Etlik City Hospital (1) · Aristotle University Of Thessaloniki (1)
United States (33) · Egypt (17) · Canada (4) · France (4) · Turkey (Türkiye) (4) · Israel (3) · Switzerland (3) · Brazil (2) · China (2) · Finland (2) · Greece (2) · Ireland (2) · Pakistan (2) · Vietnam (2) · Argentina (1)
Beverly Winikoff, MD, MPH (2) · Nesreen A Shehata, MD (2) · Patricia J Sulak, MD (2) · Abimbola O. Famuyide, MBBS (1) · Ahmed Maged (1) · Ahmed Maged, MD (1) · Ahmed S Alnuaimi, PhD (1) · Alaa A Hussein, FICOG, MD (1) · Alan T Tita, MD, PhD (1) · Amanda Yunker, DO (1)
PMID 12738159, PMID 16108235, PMID 16309682, PMID 16934269, PMID 17012482, PMID 17027730, PMID 19955104, PMID 20378611, PMID 20472114, PMID 20554319, PMID 21162725, PMID 22227638, PMID 23635728, PMID 23728648, PMID 24405687, PMID 24682613, PMID 24788209, PMID 25571934, PMID 25594352, PMID 25600160, PMID 26079202, PMID 26118386, PMID 26226243, PMID 26534874, PMID 26698831, PMID 26952346, PMID 27419258, PMID 27558956, PMID 27607864, PMID 28456509, PMID 29141040, PMID 31226322, PMID 31304593, PMID 31736069, PMID 31777949, PMID 32143721, PMID 32176833, PMID 32448257, PMID 32649493, PMID 33169839, PMID 33232518, PMID 33713384, PMID 34932836, PMID 37116825, PMID 37769311, PMID 38954680, PMID 39326051, PMID 39934771, PMID 40345697, PMID 41114449
2005 (1), 2009 (1), K12HD001258 (1), R21HD091337 (1)