129 completed, 10 unknown, 7 recruiting, 5 terminated. 35 Phase 1, 30 Phase 3, 27 Phase 2, 27 Phase 4, 18 Not applicable.
Follow Levonorgestrel: new trials by email Literature Review of Levonorgestrel trials Research Report on Levonorgestrel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rct Assessing Pregnancy - Piroxicam for Ec With Levonorgestrel Levonorgestrel 1.5 mg and Piroxicam 40 mg, Oral LNG + Placebo - Emergency Contraception, Contraception | Phase 3 | Not yet recruiting | University of Utah | 1458 | 2027-03-01 | 2026-03-04 |
| Efficacy, Safety, and Tolerability of Levonorgestrel Vaginal System Levonorgestrel - Contraceptive Usage | Phase 3 | Not yet recruiting | Chemo Research | 1600 | 2026-12-01 | 2026-07-29 |
| Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometrium Wegovy, Mirena - Endometrial Cancer, Atypical Hyperplasia | Phase 2 | Recruiting | GynOncTrials | 71 | 2026-09-17 | 2026-10-05 |
| The Influence of Plan B® on Cardiovascular Health. Plan B (Levonorgestrel), Placebo (gelatin capsule) - Female, Premenopausal | Not applicable | Recruiting | McMaster University | 40 | 2026-07-22 | 2026-10-14 |
| Effects of Copper Versus Levonorgestrel Intrauterine Devices on Mucosal Microbiota and Barrier Function Among Young African Women Levonorgesterel Intrauterine system (LNG IUS), Copper T Intrauterine device (Cu-IUD) - Vaginal Microbial Diversity | Not applicable | Not yet recruiting | Seattle Children's Hospital | 120 | 2026-07-01 | 2026-06-04 |
| Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Ethinyl Estradiol/Levonorgestrel (EE/LNG) Ethinyl Estradioll/Levonorgestrel (EE/LNG), Bemnifosbuvir/Ruzasvir (BEM/RZR), Bemnifosbuvir/Ruzasvir (BEM/RZR) + Ethinyl Estradioll/Levonorgestrel (EE/LNG) - Healthy Volunteer Study | Phase 1 | Completed | Atea Pharmaceuticals, Inc. | 24 | 2025-12-04 | 2026-04-13 |
| Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study Levonorgestrel Intrauterine System, Norethindrone Acetate - Heavy Menstrual Bleeding, Bleeding Disorder | Recruiting | Oregon Health and Science University | 300 | 2025-09-24 | 2025-12-17 | |
| A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity AZD6234, Ethinyl estradiol/Levonorgestrel (EE/LEVO), Acetaminophen (APAP) - Healthy Participants | Phase 1 | Active not recruiting | AstraZeneca | 100 | 2025-06-04 | 2026-10-13 |
| Postplacental Copper Intrauterine Device Versus Postpartum Progesterone-only Pills on Uterine Niche Formation Primary Cesarean Section, immediate postplacental insertion of a copper T380A intrauterine device, progesterone-only pills - Scar Niche, Myometrial Remodeling | Not applicable | Completed | Benha University | 750 | 2025-02-12 | 2026-02-27 |
| Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency Contraception Levonorgestrel, Piroxicam, Ulipristal Acetate - Contraception | Phase 3 | Recruiting | The University of Hong Kong | 980 | 2025-01-18 | 2026-05-14 |
| Assessing the Efficacy and Acceptability of Two Missed Period Pills Regimens Levonorgestrel, Mifepristone - Pregnancy Early, Pregnancy Related | Phase 2 / Phase 3 | Unknown | Gynuity Health Projects | 286 | 2024-07-22 | 2024-07-18 |
| A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause NNC0519-0130, Levonorgestrel + Ethinylestradiol, Paracetamol - Diabetes Mellitus, Type 2 | Phase 1 | Completed | Novo Nordisk A/S | 47 | 2024-07-18 | 2026-03-12 |
| Comparison of Two PPOS Models for Pituitary Suppression Cerazet - Infertility, Female, Fertility Disorders | Not applicable | Unknown | NextFertility | 210 | 2024-07-01 | 2024-06-18 |
| A Research Study Looking at How the Compound NNC0487-0111 Works With Birth Control Pills and Affects Emptying of the Stomach in Women Not Able to Become Pregnant NNC0487-0111 A, NNC0487-0111 C, Levonorgestrel 150 μg + Ethinylestradiol 30 μg (Oral contraceptive OC) - Obesity | Phase 1 | Completed | Novo Nordisk A/S | 43 | 2024-06-14 | 2025-05-08 |
| A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children. NNC0194-0499, ethinylestradiol/levonorgestrel - Healthy Volunteers (Non-alcoholic Steatohepatitis) | Phase 1 | Completed | Novo Nordisk A/S | 34 | 2023-12-18 | 2025-02-18 |
| Phase II Study of Ovulation in Obese Women Levonorgestrel 1.5 milligram, Meloxicam 15 milligram, calcium carbonate 750 milligram - Pregnancy Prevention | Phase 2 | Completed | InnovaGyn, Inc. | 4 | 2023-12-10 | 2026-06-30 |
| Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start Levonorgestrel 52 MG Intrauterine System - Contraception | Phase 4 | Recruiting | University of Utah | 1404 | 2022-11-07 | 2026-04-16 |
| Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days Levonorgestrel 1.5mg, Meloxicam 15 mg, Placebo - Pregnancy Prevention | Phase 2 | Completed | InnovaGyn, Inc. | 19 | 2022-06-28 | 2026-09-09 |
| Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia Intensive Lifestyle Intervention (ILI), Megestrol Acetate 160 MG Oral Tablet, Levonorgestrel-Releasing Intrauterine Contraceptive System (Mirena), 52 Mg - Atypical Endometrial Hyperplasia, Fertility Issues | Phase 2 / Phase 3 | Recruiting | Xiaojun Chen | 172 | 2022-06-13 | 2026-06-04 |
| Bioavailability of Levonorgestrel and Ethinyl Estradiol Tablets 15.0 mg/0.03 mg With Regards to Reference Product Levonorgestrel 15.0 mg and Ethinyl estradiol 0.03 mg Test Drug, Microgynon CD - Therapeutic Equivalency | Phase 1 | Completed | Laboratorios Andromaco S.A. | 36 | 2022-02-26 | 2022-06-02 |
Showing 20 of 159. Sign in to see all of them.
Menorrhagia (13) · Endometriosis (6) · Endometrial Hyperplasia (5) · Obesity (5) · Acquired Immunodeficiency Syndrome (4) · HIV Infections (4) · Amenorrhea (3) · Diabetes Mellitus, Type 2 (3) · Infertility (3) · Adenomyosis (2) · Anorexia Nervosa (2) · Contraception Behavior (2) · Diabetes Mellitus (2) · Dysmenorrhea (2) · Endometrial Neoplasms (2)
Bayer (35) · University of Utah (6) · Pfizer (5) · FHI 360 (4) · Novo Nordisk A/S (4) · University of Colorado, Denver (4) · AstraZeneca (3) · Duramed Research (3) · Laboratorios Andromaco S.A. (3) · Oregon Health and Science University (3) · University of Pittsburgh (3) · Wyeth is now a wholly owned subsidiary of Pfizer (3) · Boehringer Ingelheim (2) · Columbia University (2) · Gynuity Health Projects (2)
United States (60) · Germany (12) · United Kingdom (10) · Sweden (9) · Canada (8) · Spain (8) · France (7) · Brazil (6) · Netherlands (6) · Belgium (5) · Kenya (5) · Mexico (5) · Norway (5) · Chile (4) · China (4)
Andrea Olariu, MD, PhD (2) · David Turok, MD, MPH (2) · Diana Blithe, PhD (2) · Abimbola O. Famuyide, MBBS (1) · Alicia Smith, PhD (1) · Alison Edelman, MD (1) · Alison Edelman, MD, MPH (1) · Allison Wheeler (1) · Andrea Lukes, MD (1)
PMID 23114735, PMID 26830816, PMID 12441312, PMID 15471507, PMID 15541405, PMID 16009156, PMID 16102549, PMID 16798842, PMID 16855077, PMID 16980507, PMID 17077229, PMID 17434015, PMID 18653184, PMID 18929686, PMID 19698816, PMID 19933235, PMID 19955104, PMID 20034000, PMID 20116841, PMID 20378611, PMID 20472114, PMID 20733445, PMID 21074011, PMID 21417562, PMID 21475963, PMID 21632810, PMID 22222193, PMID 22429273, PMID 22959906, PMID 23040128, PMID 23340271, PMID 23512637, PMID 23562364, PMID 23635728, PMID 23744513, PMID 24388695, PMID 24682613, PMID 24713413, PMID 24726226, PMID 24785854, PMID 24835831, PMID 24986712, PMID 25129340, PMID 25242443, PMID 25259677, PMID 25283586, PMID 25385099, PMID 25393993, PMID 25504028, PMID 25934164
2018 (3), 2008 (2), 2017 (2), 2023 (2), 2004 (1), 2005 (1), 2014 (1), 2016 (1), 2019 (1), K12HD001271 (1), R01AI155052 (1), R01DE016212 (1), R01HD043869 (1), R01HD072663 (1), R01HD085887 (1)