42 unknown, 39 completed, 24 recruiting, 15 not yet recruiting. 48 Not applicable, 10 Phase 3, 9 Phase 4, 8 Phase 2, 7 Early Phase 1.
Follow Adenomyosis: new trials by email Literature Review of Adenomyosis trials Research Report on Adenomyosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Linzagolix in Adenomyosis and Recurrent Implantation Failure Linzagolix 200 mg (Yselty) - Adenomyosis of Uterus, Implantation Failure | Not yet recruiting | Vida Fertility Institute | 30 | 2027-01-01 | 2026-10-21 | |
| Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery DEX 0.2 μg/kg/h., SGB, 0.9% Sodium Chloride (Placebo) - Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus | Not applicable | Recruiting | Catherin Zhang | 100 | 2026-10-01 | 2026-10-06 |
| The Efficacy of High-Intensity Focused Ultrasound Therapy on Adenomyosis High Intensity Focused Ultrasound - Adenomyosis of Uterus | Not yet recruiting | Far Eastern Memorial Hospital | 20 | 2026-09-16 | 2026-09-08 | |
| Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine Endometriosis, Adenomyosis of Uterus | Recruiting | Semmelweis University | 1600 | 2026-09-01 | 2026-09-18 | |
| Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain Custom-formulated, high-CBD study product, Placebo - Endometriosis, Adenomyosis | Phase 1 / Phase 2 | Recruiting | Staci Gruber, Ph.D. | 60 | 2026-09-01 | 2026-07-27 |
| Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery Standard Surgical Procedures for Benign Gynecological Conditions - Benign Gynecological Disease, Uterine Fibroids | Not yet recruiting | IRCCS San Raffaele | 6000 | 2026-09-01 | 2026-08-19 | |
| Impact of Educational Videos on Pre-operative Anxiety educational video - Endometriosis, Fibroids | Not applicable | Enrolling by invitation | UConn Health | 60 | 2026-07-17 | 2026-08-03 |
| Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy Cyclobenzaprine - Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified | Phase 4 | Not yet recruiting | Christiana Care Health Services | 36 | 2026-07-01 | 2026-06-24 |
| Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet - Leiomyoma, Uterine, Benign Gynecological Disease | Not applicable | Recruiting | Fatih Sultan Mehmet Training and Research Hospital | 160 | 2026-07-01 | 2026-07-30 |
| FET in Adenomyosis GnRH agonist downregulation, GnRH agonist and Letrozole - Adenomyosis | Not applicable | Not yet recruiting | Indira IVF Hospital Pvt Ltd | 700 | 2026-06-25 | 2026-01-26 |
| Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding Radiofrequency endometrial ablation, Uterine artery embolization, Hysterectomy - Abnormal Uterine Bleeding Due to Adenomyosis (Disorder) | Not applicable | Recruiting | University Hospital, Bordeaux | 230 | 2026-04-17 | 2026-04-20 |
| Pelvic Floor Muscle Function and Endometriosis-Related Pelvic Pain Endometriosis, Chronic Pelvic Pain | Recruiting | University of Pecs | 100 | 2026-04-01 | 2026-07-20 | |
| Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss Endometrial Biopsy, Vaginal Swab, Blood sample - Recurrent Implantation Failure, Recurrent Pregnancy Loss | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 100 | 2026-04-01 | 2026-02-05 |
| Efficacy and Tolerability of TENS in Endometriosis-related Pain Conventional TENS, Microstimulation TENS - Pelvic Pain Associated With Endometriosis or Adenomyosis, Pelvic Pain Associated With Refractory Endometriosis | Not applicable | Recruiting | Monath Electronic | 92 | 2026-03-15 | 2026-03-31 |
| Central Sensitization in Women With Adenomyosis: Prevalence, Risk Factors, and Therapeutic Failure Adenomyosis | Active not recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 1200 | 2025-12-09 | 2026-03-06 | |
| The Good Pain Consultation in Endometriosis. pain consultation, biopsychosocial pain education + usual care, Usual Care - Pelvic Pain Syndrome, Endometriosis | Not applicable | Recruiting | Sorlandet Hospital HF | 110 | 2025-11-01 | 2026-04-28 |
| A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes total hysterectomy, subtotal hysterectomy - Fibroid Uterus, Metrorrhagia | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2025-10-01 | 2025-09-05 |
| Comparing the Efficacy of TU-LESS and vNOTES for Hysterectomy of Enlarged Uterus TU-LESS, vNOTES - Enlarged Uterus, Adenomyosis | Not applicable | Not yet recruiting | West China Second University Hospital | 210 | 2025-10-01 | 2025-09-18 |
| Nintedanib for Improving Reproductive Outcomes in Adenomyosis Nintedanib, Progesterone - Adenomyosis of Uterus | Phase 3 | Not yet recruiting | Sun Yat-sen University | 328 | 2025-09-01 | 2025-09-09 |
| Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology) Robotic Assisted-Surgery (RAS) Hysterectomy - Uterine Fibroids (UF), Menstrual Disorders | Not applicable | Active not recruiting | Medtronic - MITG | 70 | 2025-08-28 | 2026-06-02 |
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Endometriosis (41) · Leiomyoma (30) · Dysmenorrhea (14) · Metrorrhagia (14) · Menorrhagia (12) · Myofibroma (11) · Pelvic Pain (11) · Infertility (9) · Endometrial Neoplasms (6) · Infertility, Female (5) · Ovarian Neoplasms (5) · Pain (5) · Uterine Cervical Neoplasms (5) · Uterine Prolapse (3)
Female Urogenital Diseases (140) · Female Urogenital Diseases and Pregnancy Complications (140) · Genital Diseases (140) · Urogenital Diseases (140) · Genital Diseases, Female (138) · Uterine Diseases (138) · Pathological Conditions, Signs and Symptoms (48) · Neoplasms (46) · Neoplasms by Histologic Type (40) · Neoplasms, Connective and Soft Tissue (40) · Pathologic Processes (37) · Signs and Symptoms (33) · Neoplasms, Muscle Tissue (32) · Neurologic Manifestations (30) · Pain (24)
Uterine Artery Embolization (6) · Gonadotropin-Releasing Hormone (5) · dienogest (5) · Hysterectomy (4) · Leuprolide (3) · Triptorelin Pamoate (3) · Bupivacaine (2) · Contraceptives, Oral, Combined (2) · High-Energy Shock Waves (2) · Letrozole (2) · Mifepristone (2) · Saline Solution (2) · Uterine Myomectomy (2) · drospirenone (2) · ulipristal acetate (2)
Assiut University (6) · Oslo University Hospital (5) · Assistance Publique - Hôpitaux de Paris (4) · National Taiwan University Hospital (4) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (3) · Taipei Veterans General Hospital, Taiwan (3) · University of Texas Southwestern Medical Center (3) · CARE Fertility UK (2) · Chinese University of Hong Kong (2) · Far Eastern Memorial Hospital (2) · IRCCS San Raffaele (2) · Lei Li (2) · Peking Union Medical College Hospital (2) · Samsung Medical Center (2) · Turku University Hospital (2)
China (20) · United States (16) · Italy (13) · Egypt (10) · France (10) · Taiwan (9) · South Korea (7) · Turkey (Türkiye) (7) · Norway (6) · Belgium (3) · Finland (3) · Germany (3) · Hong Kong (3) · Spain (3) · United Kingdom (3)
Fulvio Zullo (2) · Jehn-Hsiahn Yang, M.D. (2) · Lei Li, M.D. (2) · Marit Lieng, PhD, MD (2) · Tina Tellum, MD (2) · Abd ElKareem Hasan, Professor (1) · Amanda Yunker, DO (1) · Arri Coomarasamy (1) · Ban L Sng, FANZCA (1) · Cheryl H Hoffman, MD (1) · Chi-Hau Chen, MD, PhD (1) · Chi-Heum Cho, MD, PhD (1)
PMID 12501064, PMID 21422864, PMID 21830244, PMID 22229256, PMID 22535729, PMID 22832421, PMID 23246186, PMID 23670744, PMID 23791399, PMID 24103533, PMID 24745831, PMID 25199746, PMID 26394736, PMID 26427702, PMID 27356477, PMID 27379972, PMID 28865548, PMID 28950327, PMID 29290809, PMID 29551477, PMID 29557233, PMID 29845696, PMID 29935649, PMID 30316443, PMID 31172324, PMID 31194884, PMID 31325591, PMID 31538078, PMID 32767677, PMID 33207939, PMID 33454995, PMID 33590656, PMID 33712099, PMID 34587658, PMID 34716161, PMID 34961515, PMID 35123042, PMID 35209847, PMID 35230489, PMID 36450938, PMID 36549997, PMID 37149412, PMID 37307001, PMID 37822471, PMID 38199630, PMID 39274438, PMID 39805535, PMID 40188683, PMID 40302212, PMID 41298256
2014 (1), 2023 (1)