32 completed, 11 unknown, 5 terminated, 5 withdrawn. 20 Phase 4, 12 Phase 3, 9 Phase 2, 5 Phase 1, 2 Early Phase 1.
Follow ulipristal acetate: new trials by email Literature Review of ulipristal acetate trials Research Report on ulipristal acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mammogram Pretreatment With Ulipristal Acetate Biospecimen Collection, Magnetic Resonance Imaging, Mammogram - Mammography Screening, Breast Density | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 26 | 2026-08-21 | 2026-09-03 |
| Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency Contraception Levonorgestrel, Piroxicam, Ulipristal Acetate - Contraception | Phase 3 | Recruiting | The University of Hong Kong | 980 | 2025-01-18 | 2026-05-14 |
| Disparities in Emergency Contraceptive Metabolism Dictate Efficacy Ulipristal acetate - Contraceptive Usage | Phase 4 | Recruiting | Oregon Health and Science University | 140 | 2023-01-09 | 2026-07-09 |
| Ulipristal Acetate for Use in Early Pregnancy Loss Ulipristal Acetate Tablets, Misoprostol Pill - Missed Abortion, Anembryonic Pregnancy | Phase 2 | Completed | University of North Carolina, Chapel Hill | 3 | 2022-05-11 | 2023-06-28 |
| Advance Provision of Postpartum Emergency Contraception and Its Effects on Reproductive Autonomy Ulipristal Acetate - Contraception, Contraceptive Usage | Completed | Northwestern University | 75 | 2022-03-01 | 2025-04-27 | |
| Study of the Safety and Efficacy of Ulipristal Acetate (UPA) Used Daily as a Contraceptive Ulipristal acetate - Contraception, Healthy Female | Phase 2 | Withdrawn | Premier Research | 2020-12-01 | 2025-11-20 | |
| Ovarian Function With ENG Implant and UPA Use ENG implant, oral ulipristal acetate - Contraception | Early Phase 1 | Completed | University of Utah | 40 | 2020-09-04 | 2024-07-12 |
| Quality of Life Outcomes for Ulipristal Acetate and Tranexamic Acid in the Management of Heavy Menstrual Bleeding UPA, TEA, Placebo (for UPA) - Heavy Menstrual Bleeding | Phase 1 | Withdrawn | University of Saskatchewan | 2020-01-01 | 2020-01-28 | |
| Advance Provision of Medication Abortion Mifeprex® (Mifepristone 200 mg), Misoprostol 800 mcg, ella® (ulipristal acetate emergency contraception 30 mg) - Early Abortion | Phase 4 | Withdrawn | University of California, San Francisco | 2020-01-01 | 2019-05-30 | |
| Ulipristal Acetate in Symptomatic Uterine Fibroid Ulipristal Acetate 5 mg - Uterine Fibroid, Heavy Menstrual Bleeding | Phase 4 | Terminated | Mỹ Đức Hospital | 25 | 2019-10-23 | 2020-04-13 |
| Liver Safety Assessment During Ulipristal Acetate Treatment for Uterine Fibroids (LISA) Ulipristal Acetate - Leiomyoma, Uterine, Liver Injury | Terminated | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 30 | 2019-05-23 | 2024-05-20 | |
| Ulipristal Acetate for Cervical Preparation Ulipristal Acetate - Termination of Pregnancy | Early Phase 1 | Completed | Stanford University | 13 | 2019-04-16 | 2020-07-01 |
| Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion Ulipristal Acetate, Misoprostol - Induction of Second Trimester Abortion | Phase 4 | Completed | Ain Shams University | 24 | 2019-01-01 | 2021-08-04 |
| Study Comparing Emergency Contraception Effectiveness in Women Who Weight ≥ 80 kg Ulipristal Acetate, Levonorgestrel - Contraception | Phase 4 | Terminated | Kimberly Myer | 532 | 2018-07-12 | 2025-11-20 |
| On Demand Contraception: Ulipristal Acetate Plus a COX-2 Inhibitor at Peak Fertility Ulipristal Acetate 30 MG Oral Tablet - Contraception | Phase 1 | Completed | Stanford University | 12 | 2018-03-15 | 2019-06-25 |
| Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis Ulipristal Acetate - Adenomyosis, Heavy Uterine Bleeding | Phase 4 | Withdrawn | Vanderbilt University Medical Center | 2018-02-01 | 2018-02-08 | |
| Impact of Esmya on Fertility to Infertile Women With Fibroids Managed With Assisted Reproduction Techniques ULIPRISTAL ACETATE - Infertility, Female, Fibroid Uterus | Completed | ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO | 127 | 2017-12-29 | 2019-01-09 | |
| Ulipristal Versus Placebo for Women With Bleeding Induced by Mirena Ulipristal acetate, Placebo - Heavy Menstrual Bleeding, Abnormal Bleeding | Phase 4 | Unknown | University of Campinas, Brazil | 32 | 2017-07-01 | 2018-05-03 |
| Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA UPA-ECx1, UPA-ECx2 - Obesity, Contraception | Phase 4 | Completed | Oregon Health and Science University | 64 | 2017-05-30 | 2024-02-06 |
| A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions Use Phase (Ulipristal Acetate, 30 mg) - Emergency Contraception | Phase 3 | Completed | HRA Pharma | 1270 | 2017-05-23 | 2022-12-02 |
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Leiomyoma (20) · Menorrhagia (4) · Infertility (3) · Adenomyosis (2) · Breast Neoplasms (2) · Contraception Behavior (2) · Dysmenorrhea (2) · Hemorrhage (2) · Infertility, Female (2) · Uterine Hemorrhage (2) · Abortion, Missed (1) · Body Weight (1) · Constipation (1) · Dilatation, Pathologic (1) · Endometriosis (1)
HRA Pharma (5) · PregLem SA (5) · University Magna Graecia (4) · Allergan (3) · Oregon Health and Science University (3) · Columbia University (2) · Northwestern University (2) · Premier Research (2) · Stanford University (2) · The University of Hong Kong (2) · ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO (1) · Ain Shams University (1) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1)
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Fulvio Zullo, MD,PhD (4) · Roberta Venturella, MD (3) · Anna Chan (2) · Dr Elke Bestel (2) · Abigail Liberty (1) · Alison Edelman, MD (1) · Almereau Prollius, MD (1) · Amanda Yunker, DO (1) · Ashley M Turner, MD MSc (1) · Carlos Morente, MD (1) · Carolyn L Westhoff, MD (1) · Carolyn Westhoff, MD (1)
PMID 22296075, PMID 24630081, PMID 30969201, PMID 31444600, PMID 18448745, PMID 20634186, PMID 22296076, PMID 24457604, PMID 25542821, PMID 25994664, PMID 26477496, PMID 29420395, PMID 30130351, PMID 30239831, PMID 30303900, PMID 30871768, PMID 31777949, PMID 32033718, PMID 35015210, PMID 35470225, PMID 35576349, PMID 38663539, PMID 42387351
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