495 completed, 144 unknown, 70 recruiting, 46 not yet recruiting. 407 Not applicable, 114 Phase 3, 74 Phase 2, 63 Phase 4, 28 Phase 1.
Follow Menstruation Disturbances: new trials by email Literature Review of Menstruation Disturbances trials Research Report on Menstruation Disturbances
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation Disorders Ginger, Placebo - Women With Coagulation Disorders | Early Phase 1 | Not yet recruiting | University of Valladolid | 74 | 2028-02-01 | 2026-05-19 |
| Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With Endometriosis Desloratadine, Placebo - Endometriosis, Endometriosis (Diagnosis) | Phase 2 | Not yet recruiting | Medical University of Vienna | 60 | 2027-02-01 | 2026-09-18 |
| The SPARK-PMDD Study Premenstrual Dysphoric Disorder, PMDD | Not yet recruiting | King's College London | 120 | 2027-01-01 | 2026-08-18 | |
| Effect of Semiconductor Embedded Wearable Sleeve on Treatment of Primary Dysmenorrhea Symptoms Semiconductor embedded body sleeve, Placebo Non-Compressive Body Sleeve - Primary Dysmenorrhea, Primary Dysmenorrhea (PD) | Not applicable | Not yet recruiting | University of California, Davis | 100 | 2026-12-01 | 2026-06-16 |
| MLS101 Study in PMDD MLS101 psilocybin, Placebo capsules - Premenstrual Dysphoric Disorder ( PMDD), PMDD | Phase 1 | Not yet recruiting | MycoMedica Life Sciences PBC | 32 | 2026-12-01 | 2026-09-14 |
| The Effect of Mandala Coloring, Sleep Quality, Anxiety With Premenstrual Syndrome Mandala coloring group - Premenstrual Syndrome | Not applicable | Not yet recruiting | Kırklareli University | 80 | 2026-11-01 | 2026-08-25 |
| Transcutaneous Cervical Vagus Nerve Stimulation for Primary Dysmenorrhea Transcutaneous Cervical Vagus Nerve Stimulation, Sham Transcutaneous Cervical Vagus Nerve Stimulation - Primary Dysmenorrhea (PD), Menstrual Pain | Not applicable | Not yet recruiting | Sinop University | 70 | 2026-10-31 | 2026-10-19 |
| Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause transcutaneous auricular neurostimulation (tAN) - Perimenopause, PMDD | Not applicable | Enrolling by invitation | Texas Christian University | 20 | 2026-10-22 | 2026-10-23 |
| Anti-Inflammatory Diet and Physical Activity for Reproductive Health in Adolescent Girls Anti-Inflammatory Dietary Intervention, Physical Activity and Training Programme - Reproductive Health | Not applicable | Recruiting | Poznan University of Physical Education | 100 | 2026-10-20 | 2026-09-22 |
| High Intensity Interval Training Versus Mat Pilates in Women With PCOS High-Intensity Interval Training (HIIT), Mat Pilates group, General mobility exercises - Polycystic Ovarian Syndrome (PCOS), Quality of Life | Not applicable | Not yet recruiting | Riphah International University | 60 | 2026-10-20 | 2026-10-15 |
| The Effect of a Ginger Formula on Menstrual Health vs a Placebo Ginger formula, Placebo - Painful Menstruation | Not applicable | Not yet recruiting | Givaudan France Naturals | 250 | 2026-10-20 | 2026-10-26 |
| The Effects of Manual Lymphatic Drainage and Self-Manual Lymphatic Drainage Manual Lymphatic Drainage (MLD), Self-Manual Lymphatic Drainage (Self-MLD), Sham Manual Lymphatic Drainage (Sham MLD) - Premenstrual Syndrome | Not applicable | Not yet recruiting | Izmir Democracy University | 60 | 2026-10-05 | 2026-09-11 |
| A Clinical Trial to Evaluate the Effects of the Kaia Relief - Cycle System on Premenstrual Symptom Severity, Menstrual Discomfort, and Overall Well-Being in Premenopausal Women. Kaia Relief - Cycle System (Day and Night) - Premenstrual Syndrome, Menstrual Discomfort | Not applicable | Recruiting | Vivance Group | 45 | 2026-10-01 | 2026-10-15 |
| Brain and Blood Vessel Health Following Endometriosis Treatment in People With Endometriosis Investigate how norethindrone acetate, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health, Investigate how Orlissa, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health, Investigate how Oriahnn, a commonly used medication used to treat symptoms of endometriosis, impact biomarkers of brain health - Endometriosis, Endometriosis and Dysmenorrhea | Phase 4 | Not yet recruiting | Colorado State University | 45 | 2026-10-01 | 2026-09-02 |
| Whole-Body Vibration and Aerobic Exercise for Primary Dysmenorrhea in Young Adult Women Whole-Body Vibration Training, Aerobic Exercise Training - Primary Dysmenorrhea | Not applicable | Not yet recruiting | Gaziantep Islam Science and Technology University | 66 | 2026-10-01 | 2026-10-05 |
| THE EFFECT OF A REFLEXOLOGY PROGRAM ON PREMENSTRUAL SYNDROME SYMPTOMS, QUALİTY OF LİFE AND GENERAL COMFORT Foot Reflexology Massage - Premenstrual Syndrome-PMS | Not applicable | Not yet recruiting | Dokuz Eylul University | 120 | 2026-10-01 | 2026-09-03 |
| Vaginal Sildenafil for Primary Dysmenorrhea Sildenafil citrate vaginal suppository - Dysmenorrhea, Menstrual Pain | Phase 1 | Not yet recruiting | Kevin Hellman | 10 | 2026-10-01 | 2026-09-25 |
| Heavy Menstrual Bleeding and Dysmenorrhea Among Undergraduate Females in the Faculty of Medicine of Assiut University Dysmenorrhea, Heavy Menstrual Bleeding | Not yet recruiting | Assiut University | 486 | 2026-10-01 | 2026-10-01 | |
| Effect of Virtual Reality on Pain and Anxiety in Women With Dysmenorrhea Virtual Reality - Primary Dysmenorrhea, Menstrual Pain | Not applicable | Not yet recruiting | Tokat Gaziosmanpasa University | 68 | 2026-09-30 | 2026-10-07 |
| Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea Abdominal manual mobilization, Sham manual contact - Dysmenorrhea, Endometriosis | Not applicable | Not yet recruiting | Vrije Universiteit Brussel | 80 | 2026-09-01 | 2026-06-12 |
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Dysmenorrhea (322) · Menorrhagia (200) · Premenstrual Syndrome (176) · Endometriosis (67) · Leiomyoma (65) · Amenorrhea (63) · Pain (54) · Premenstrual Dysphoric Disorder (42) · Polycystic Ovary Syndrome (41) · Pelvic Pain (38) · Metrorrhagia (36) · Motor Activity (30) · Dyspareunia (24) · Depression (22)
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PMID 34878624, PMID 37523477, PMID 29476499, PMID 32621325, PMID 32945631, PMID 33650259, PMID 33963686, PMID 29855308, PMID 31971678, PMID 36357960, PMID 37477173, PMID 37863160, PMID 41868592, PMID 19546766, PMID 20353434, PMID 21043553, PMID 21521204, PMID 23188490, PMID 23925396, PMID 24411158, PMID 24579886, PMID 24856936, PMID 28525302, PMID 30724096, PMID 30865281, PMID 30992150, PMID 31069056, PMID 31227284, PMID 31654294, PMID 31985138, PMID 32034419, PMID 32769633, PMID 32835865, PMID 33066973, PMID 33544889, PMID 33564263, PMID 33596357, PMID 34134684, PMID 34553161, PMID 34582715, PMID 35415708, PMID 35675604, PMID 35717987, PMID 36116480, PMID 36708012, PMID 37183454, PMID 37283994, PMID 37335817, PMID 37982388, PMID 38335228
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