29 completed, 9 unknown, 3 not yet recruiting, 3 terminated. 23 Not applicable, 7 Phase 4, 6 Phase 3, 2 Phase 2.
Follow Upper Gastrointestinal Bleeding: new trials by email Literature Review of Upper Gastrointestinal Bleeding trials Research Report on Upper Gastrointestinal Bleeding
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding Trimebutine Maleate, Placebo - Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 100 | 2026-09-01 | 2026-08-06 |
| Acute Kidney Injury in Upper GI Bleeding Patients Observational assessment - Upper Gastrointestinal Bleeding, Acute Kidney Injury | Not yet recruiting | Sohag University | 200 | 2026-05-15 | 2026-06-09 | |
| HALP as a Novel Score for Prediction of Mortality and re_bleeding in Upper GIT Bleeding Upper endoscopy - Upper Gastrointestinal Bleeding | Not yet recruiting | Sohag University | 100 | 2025-08-08 | 2025-08-11 | |
| HFNC Versus Conventional Oxygen Therapy in Prolonged Upper Gastrointestinal Endoscopy in the ICU High-flow nasal cannula (HFNC), Conventional nasal oxygen therapy (COT), Upper gastrointestinal endoscopy (UGE) including gastroscopy - Upper Gastrointestinal Bleeding | Not applicable | Completed | Ain Shams University | 70 | 2024-04-10 | 2024-10-29 |
| Gastric CLEANsing by Intravenous AZithromycin in Urgent Endoscopy Azithromycin, Saline solution - Upper Gastrointestinal Bleeding | Not applicable | Completed | Clinical Hospital Colentina | 224 | 2023-10-01 | 2026-01-16 |
| PuraStat® Combined With Adrenaline Versus Standard of Care in Upper Gastrointestinal Bleeding PuraStat® combined with Adrenaline, Standard of Care - Upper Gastrointestinal Bleeding | Not applicable | Recruiting | Tallaght University Hospital | 126 | 2023-10-01 | 2025-03-26 |
| Awareness of Iron Status Evaluation in UGIB Upper Gastrointestinal Bleeding | Completed | Hat Yai Medical Education Center | 867 | 2023-08-01 | 2024-03-07 | |
| Single-use Versus Reusable Gastroscopes in Patients With Upper Gastrointestinal Bleeding. Endoscopic hemostasis using a Esophagogastroduodenoscopy - Upper Gastrointestinal Bleeding | Not applicable | Unknown | University Hospital Augsburg | 150 | 2023-03-27 | 2024-01-31 |
| Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding Metoclopramide, Placebo - Upper Gastrointestinal Bleeding | Phase 3 | Completed | Universidad Autonoma de Nuevo Leon | 50 | 2023-03-01 | 2024-10-09 |
| Prophylactic Antibiotics in Prevention of Spontaneous Bacterial Peritonitis in Compensated Liver Cirrhosis Third generation cephalosporin antibiotics - Liver Cirrhosis, Upper Gastrointestinal Bleeding | Unknown | Assiut University | 80 | 2022-12-01 | 2022-10-28 | |
| Anticoagulation With Enhanced Gastrointestinal Safety Clinician Notification with Nurse Facilitation (CNNF), Wait list control - Upper Gastrointestinal Bleeding, Peptic Ulcer Hemorrhage | Not applicable | Completed | University of Michigan | 341 | 2022-10-05 | 2024-04-30 |
| PillSense System for Detecting UGI Bleed PillSense - UGI Bleed, Upper Gastrointestinal Bleeding | Not applicable | Completed | EnteraSense Limited | 131 | 2021-12-10 | 2023-10-26 |
| OTSC vs. Angiographic Embolization in Patients With Refractory Non-variceal Upper Gastrointestinal Bleeding The OTSC® System Set, angiographic embolization - Upper Gastrointestinal Bleeding | Not applicable | Recruiting | Chinese University of Hong Kong | 236 | 2021-11-27 | 2026-10-22 |
| Anticoagulation With Enhanced Gastrointestinal Safety (AEGIS) Trial Clinician notification, Clinician Notification with Nurse Facilitation, Clinician Notification / Patient Activation - Upper Gastrointestinal Bleeding | Not applicable | Completed | University of Michigan | 80 | 2021-10-11 | 2023-06-29 |
| Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -A Pilot Study PillSense System - Upper Gastrointestinal Bleeding | Not applicable | Completed | EnteraSense Limited | 30 | 2021-05-07 | 2022-11-30 |
| Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -Healthy Volunteers Study PillSense System - Upper Gastrointestinal Bleeding | Not applicable | Completed | EnteraSense Limited | 10 | 2021-02-11 | 2022-11-30 |
| HemoPill Acute ® in Suspected Nonvariceal Upper Gastrointestinal Bleeding HemoPill Acute ® - Upper Gastrointestinal Bleeding | Not applicable | Completed | Wuerzburg University Hospital | 73 | 2020-10-08 | 2024-07-10 |
| Metoclopramide, Azithromycin, or Nondrug Pretreatment for UGIB to Reduce Second Endoscopy Azithromycin Injection, Metoclopramide Injectable Solution, Sodium chloride 0.9% - Gastro Intestinal Bleeding, Upper Gastrointestinal Bleeding | Phase 2 | Unknown | Waihong Chung | 435 | 2020-07-01 | 2020-08-07 |
| Thoracic Ultrasound on Upper Gastrointestinal Bleeding (ECOBLEDSTUDY) Upper Gastrointestinal Bleeding | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 110 | 2019-07-01 | 2020-01-02 | |
| Non-warfarin Oral AntiCoagulant Resumption After Gastrointestinal Bleeding in Atrial Fibrillation Patients restart NOAC very early, restart NOAC early - Upper Gastrointestinal Bleeding | Not applicable | Unknown | Chinese University of Hong Kong | 552 | 2019-03-11 | 2020-05-05 |
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Gastrointestinal Hemorrhage (48) · Emergencies (5) · Acute Kidney Injury (2) · Hematemesis (2) · Hemorrhage (2) · Hypertension, Portal (2) · Liver Cirrhosis (2) · Melena (2) · Peptic Ulcer (2) · Anemia (1) · Atrial Fibrillation (1) · Duodenal Ulcer (1) · Esophageal and Gastric Varices (1) · Fibrosis (1) · Heart Defects, Congenital (1)
Digestive System Diseases (48) · Gastrointestinal Diseases (48) · Pathologic Processes (48) · Pathological Conditions, Signs and Symptoms (48) · Hemorrhage (46) · Disease Attributes (5) · Liver Diseases (5) · Duodenal Diseases (3) · Intestinal Diseases (3) · Signs and Symptoms (3) · Stomach Diseases (3) · Cardiovascular Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Fibrosis (2)
Esomeprazole (3) · Azithromycin (2) · Epinephrine (2) · Famotidine (2) · Metoclopramide (2) · Saline Solution (2) · Standard of Care (2) · Endoscopy (1) · Endoscopy, Digestive System (1) · Endosonography (1) · Erythrocyte Indices (1) · Erythrocyte Transfusion (1) · Erythromycin (1) · Erythromycin Estolate (1) · Gastric Lavage (1)
Chinese University of Hong Kong (5) · EnteraSense Limited (3) · Assistance Publique - Hôpitaux de Paris (2) · Assiut University (2) · Boston Children's Hospital (2) · Sohag University (2) · University of Michigan (2) · Ain Shams University (1) · AstraZeneca (1) · Bausch Health Americas, Inc. (1) · Casa Sollievo della Sofferenza IRCCS (1) · Changhai Hospital (1) · Changhua Christian Hospital (1) · Clinical Hospital Colentina (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1)
United States (11) · Hong Kong (4) · Egypt (3) · Brazil (2) · China (2) · Czechia (2) · France (2) · Germany (2) · Mexico (2) · South Korea (2) · Spain (2) · Taiwan (2) · Thailand (2) · Australia (1) · Austria (1)
Ahmed M Mohamed, MD (1) · Alexander Meining, Prof. Dr. (1) · Andrew Meltzer, MD (1) · Andriulli Angelo, MD (1) · Aric Josun Hui, MD (1) · Ben D Albert, MD (1) · Bogdan Mateescu, Prof (1) · Boris R Gelfand, Prof (1) · Celina Lacet, Doctor (1) · David Collins (1) · Don Rockey, M.D (1) · Eduardo GH de Moura (1)
PMID 19086953, PMID 22681960, PMID 23281973, PMID 23398660, PMID 24790465, PMID 26134614, PMID 26417980, PMID 27156655, PMID 27641510, PMID 29064894, PMID 29803838, PMID 30733822, PMID 31634917, PMID 32119939, PMID 32600393, PMID 34932836, PMID 35090577, PMID 36906081, PMID 38065512, PMID 38240536, PMID 39241828, PMID 40110237, PMID 41114449
K23DK118179 (2)