753 completed, 129 unknown, 125 recruiting, 57 terminated. 585 Not applicable, 163 Phase 2, 109 Phase 1, 77 Phase 3, 53 Phase 4.
Follow Type 1 Diabetes: new trials by email Literature Review of Type 1 Diabetes trials Research Report on Type 1 Diabetes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Galactose as a Substrate for Post-Exercise Skeletal Muscle Glycogen Repletion in Individuals With Type 1 Diabetes galactose - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Aarhus | 16 | 2027-02-01 | 2026-08-19 |
| ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion. ENCRT-103-hPI encompasses the ENC-103 device, which will be implanted once loaded with primary islet cargo. - Type 1 Diabetes | Phase 1 | Not yet recruiting | Encellin | 10 | 2027-01-06 | 2026-08-20 |
| Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes High-Resistance Inspiratory Muscle Strength Training, Sham Inspiratory Muscle Strength Training - Type 1 Diabetes | Not applicable | Not yet recruiting | Florida State University | 30 | 2027-01-01 | 2026-10-08 |
| Verapamil In Preclinical Type 1 Diabetes Verapamil 120 Mg/24 Hours Oral Capsule, Extended Release, Placebo, blood sampling - Type 1 Diabetes | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2027-01-01 | 2026-10-22 |
| Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus Psychological Interventions for children and adolescents - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Pittsburgh | 50 | 2026-12-01 | 2026-07-07 |
| Precision T1D Platform - New Therapies for Cardio-Renal Complications Finerenone, Sotagliflozin - Type 1 Diabetes, T1D Heart Failure | Phase 2 | Not yet recruiting | Oregon Health and Science University | 57 | 2026-11-01 | 2026-08-10 |
| Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes? Mindfulness-Based Stress Reduction - Virtual Reality, Stress tip sheet - Type 1 Diabetes | Not applicable | Not yet recruiting | Wayne State University | 48 | 2026-10-31 | 2026-10-16 |
| Lean Mass Changes With Semaglutide in Adults With Type 1 Diabetes and Overweight/Obesity. Semaglutide, Placebo - Type 1 Diabetes, Overweight , Obesity | Phase 2 / Phase 3 | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 40 | 2026-10-13 | 2026-10-23 |
| Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes Insulin Self-Management Know-Find-Solve Activity Book, Routine education - Type 1 Diabetes, Children | Not applicable | Recruiting | Marmara University | 40 | 2026-10-05 | 2026-10-08 |
| Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes Next Generation Extended Wear Sensors - Type 1 Diabetes, Type 2 Diabetes | Not applicable | Recruiting | Medtronic MiniMed, Inc. | 1500 | 2026-10-05 | 2026-10-20 |
| C-Carbs: A CGM-guided Approach to Teaching Carb Awareness C-Carbs Program - Type 1 Diabetes | Not applicable | Recruiting | University of California, Los Angeles | 40 | 2026-09-30 | 2026-09-08 |
| Butyrate or Intensive Lifestyle Modification in Type 1 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease Intensive lifestyle modification (hypocaloric Mediterranean diet and promotion of physical activity), Butyrate, Intensive lifestyle modification + butyrate - Type 1 Diabetes | Not applicable | Not yet recruiting | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | 200 | 2026-09-15 | 2026-07-06 |
| Single Arm Intervention Trial of DEKA TWIIST TM Insulin Pump Utilizing Tidepool Loop Algorithm in Pregnant People With Pre-existing Type 1 Diabetes Automated Insulin Delivery (AID) - Type 1 Diabetes, Pregnancy | Not applicable | Not yet recruiting | Mayo Clinic | 32 | 2026-09-01 | 2026-09-08 |
| Targeting GLUT1 to Control Autoimmunity in Type 1 Diabetes Type 1 Diabetes, Autoimmunity | Not yet recruiting | IRCCS San Raffaele | 84 | 2026-09-01 | 2026-07-14 | |
| Evaluating the Occurrence of DKA in People With Type I Diabetes Abbott Continuous Dual Glucose Ketone Monitoring System - Type 1 Diabetes | Not yet recruiting | Abbott Diabetes Care | 1200 | 2026-09-01 | 2026-07-31 | |
| Screening For Social Determinants Of Health In Routine Diabetes Care Social Determinants of Health (SDOH) Screening and Referral - Type 1 Diabetes | Not applicable | Not yet recruiting | University of California, Los Angeles | 150 | 2026-09-01 | 2026-07-16 |
| Study of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults With Type 1 Diabetes MASLD, Type 1 Diabetes | Not yet recruiting | Sohag University | 250 | 2026-08-22 | 2026-08-06 | |
| The Impact of Early Automated Insulin Delivery (AID) Therapy on Diabetes Control and Comorbidities, and Cost-effectiveness of AID Treatment Omnipod 5, Multiple daily injections of insulin - Type 1 Diabetes | Not applicable | Recruiting | Helsinki University Central Hospital | 100 | 2026-08-15 | 2026-10-14 |
| Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D) Cherry Sports Drink - Non-Nutritive Sweetener, Type 1 Diabetes | Not applicable | Recruiting | Medical College of Wisconsin | 20 | 2026-08-05 | 2026-10-20 |
| Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM) Dexcom G7, ViewsEMR telemetry - Type 1 Diabetes, Type 2 Diabetes Treated With Insulin | Not yet recruiting | Imperial College Healthcare NHS Trust | 70 | 2026-08-01 | 2026-08-17 |
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Diabetes Mellitus, Type 1 (1207) · Diabetes Mellitus (140) · Hypoglycemia (117) · Insulin Resistance (77) · Diabetes Mellitus, Type 2 (76) · Motor Activity (49) · Hyperglycemia (29) · Obesity (16) · Autoimmune Diseases (14) · Diabetic Nephropathies (11) · Overweight (11) · Cardiovascular Diseases (10) · Feeding and Eating Disorders (10) · Depression (7) · Diabetes Complications (7)
Nutritional and Metabolic Diseases (1207) · Glucose Metabolism Disorders (1205) · Immune System Diseases (1205) · Endocrine System Diseases (1204) · Metabolic Diseases (1203) · Autoimmune Diseases (1193) · Diabetes Mellitus (1067) · Hyperinsulinism (79) · Behavior (76) · Pathological Conditions, Signs and Symptoms (69) · Signs and Symptoms (51) · Female Urogenital Diseases and Pregnancy Complications (28) · Urogenital Diseases (28) · Nutrition Disorders (23) · Body Weight (22)
Insulin (36) · Insulin Aspart (30) · Continuous Glucose Monitoring (28) · Insulin Lispro (24) · Insulin Glargine (20) · Liraglutide (19) · Exercise (17) · Glucagon (15) · Insulin Infusion Systems (14) · Blood Specimen Collection (13) · Sodium Chloride (13) · pramlintide (13) · Pancreas, Artificial (9) · Sitagliptin Phosphate (9) · Drug Delivery Systems (8)
Medtronic MiniMed, Inc. (32) · Institut de Recherches Cliniques de Montreal (31) · Rabin Medical Center (30) · University of Colorado, Denver (30) · Yale University (24) · Steno Diabetes Center Copenhagen (22) · University of Cambridge (17) · Jaeb Center for Health Research (16) · Massachusetts General Hospital (15) · University of Virginia (15) · Assistance Publique - Hôpitaux de Paris (14) · University of Alberta (13) · Joslin Diabetes Center (12) · Medical University of Graz (12) · Oregon Health and Science University (12)
United States (499) · Canada (110) · France (91) · United Kingdom (76) · Denmark (68) · Israel (51) · Italy (40) · Germany (39) · Spain (39) · China (26) · Austria (23) · Sweden (23) · Belgium (19) · Netherlands (18) · Switzerland (17)
Moshe Phillip, Prof (9) · Roman Hovorka, PhD (9) · Bruce Buckingham, MD (8) · Jordan Pinsker, MD (8) · Stephen N. Davis, MD (7) · Jessica Castle, MD (6) · John Lum, MS (6) · Remi Rabasa-Lhoret (6) · Roy W Beck, MD, PhD (6) · Sue Brown, MD (6) · Bruce A Buckingham, MD (5)
PMID 31177185, PMID 35797241, PMID 15793249, PMID 18823656, PMID 19451554, PMID 21225239, PMID 21309844, PMID 21493665, PMID 22996144, PMID 23438305, PMID 23562090, PMID 24170749, PMID 24432999, PMID 24931572, PMID 25078901, PMID 25393157, PMID 26241693, PMID 26844283, PMID 28134564, PMID 28941330, PMID 29873107, PMID 30130323, PMID 30478937, PMID 30585770, PMID 30787930, PMID 30924570, PMID 31615852, PMID 34091488, PMID 3517648, PMID 36482870, PMID 38315506, PMID 38682786, PMID 38773658, PMID 42459945, PMID 8366922, PMID 10024506, PMID 10371488, PMID 10433086, PMID 10605821, PMID 10752702, PMID 10852253, PMID 11208527, PMID 11246868, PMID 11564949, PMID 11679447, PMID 11815483, PMID 12020338, PMID 12176626, PMID 12176628, PMID 12972423
2014 (5), 2018 (4), R01DK069803 (4), R01DK085591 (4), 2019 (3), 2025 (3), K12DK094714 (3), 1DP3DK097705-01 (2), 2015 (2), K23DK119470 (2), P30DK116074 (2), R01DK059067 (2), R01DK077166 (2), R01DK122583 (2), R01DK129553 (2)