37 completed, 35 unknown, 7 not yet recruiting, 7 recruiting. 84 Not applicable, 6 Phase 2, 2 Phase 1, 2 Phase 3, 2 Phase 4.
Follow Transcranial Direct Current Stimulation: new trials by email Literature Review of Transcranial Direct Current Stimulation trials Research Report on Transcranial Direct Current Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Dose Finding Study of DAOIB Added to tDCS for AD DAOIB - Transcranial Direct Current Stimulation, Dementia | Phase 2 | Suspended | Chang Gung Memorial Hospital | 140 | 2027-01-01 | 2026-03-20 |
| Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Effect of Transcranial Direct Current Stimulation on Flywheel Resistance Training tDCS-a, tDCS-c, Sham - tDCS - Transcranial Direct Current Stimulation | Not applicable | Not yet recruiting | Federal University of Vicosa | 30 | 2026-08-25 | 2026-09-21 |
| Knee Arthroplasty Recovery With Transcranial Direct Current Stimulation Active tDCS Stimulation, Sham tDCS Stimulation - Knee Arthroplasty, Transcranial Direct Current Stimulation | Not applicable | Not yet recruiting | Women's College Hospital | 70 | 2026-05-01 | 2026-01-20 |
| Neuropathic Pain Intervention With tDCS in Brazilian Military Personnel (NeuBRAIN Trial) tDCS, sham intervention - Neuropathic Pain, Sleep Quality | Not applicable | Not yet recruiting | Hospital da Polícia Militar de Goiás | 120 | 2026-03-01 | 2025-05-29 |
| TCDS for the Treatment of Chronic Migraine Transcranial direct current stimulation (Nettle device) 2mA stimulation for 20 minutes per day - Chronic Migraine Headache, Transcranial Direct Current Stimulation | Not applicable | Not yet recruiting | University College, London | 20 | 2026-02-01 | 2025-12-04 |
| Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation for Peripheral Facial PalsyStimulation in the Treatment of Peripheral Facial Palsy Brain-Computer Interface （BCI）, Pulsed Radiofrequency （PRF）, Standard Therapy - Peripheral Facial Palsy, Pulsed Radiofrequency | Not applicable | Enrolling by invitation | Nanjing Medical University | 30 | 2025-11-30 | 2026-01-08 |
| Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome tDCS with cognitive training programme - Transcranial Direct Current Stimulation, Post-Concussion Syndrome | Not applicable | Recruiting | The Hong Kong Polytechnic University | 40 | 2025-09-01 | 2026-09-25 |
| Effects of Transcranial Direct Current Stimulation After Short-term Immobilization on Motor Learning and Hand Function in Healthy Young Adults transcranial direct current stimulation, sham transcranial direct current stimulation, immobilization - Transcranial Direct Current Stimulation | Not applicable | Not yet recruiting | Beijing Sport University | 60 | 2025-07-21 | 2025-07-30 |
| Brain Research and Integrative Neuroscience Network for COVID-19 Combination of tDCS (device) with cognitive training (behavioral), Categorization Program - Cognitive Training, Transcranial Direct Current Stimulation | Not applicable | Completed | University of Cyprus | 38 | 2024-11-15 | 2026-09-01 |
| Investigating the Effects of Transcranial Direct Current Stimulation to Different Brain Regions on Ankle Tracking Motor Learning, Motor Adaptation, and Brain Connectivity in Healthy Middle-aged and Older Adults and Patients With Subcortical Stroke cM1 transcranial direct current stimulation, cPPC transcranial direct current stimulation, iCBM transcranial direct current stimulation - Transcranial Direct Current Stimulation, Ankle | Not applicable | Unknown | National Taiwan University Hospital | 120 | 2024-07-09 | 2024-08-19 |
| Exploring the Possible Beneficial Impact of Non-invasive and Invasive Neuromodulation on Freezing of Gait in Parkinson's Disease During Different Ambulatory Complexities: An Electrophysiological and fMRI Study Transcranial direct current stimulation - Transcranial Direct Current Stimulation | Not applicable | Recruiting | China Medical University Hospital | 20 | 2024-04-30 | 2024-08-21 |
| Effects of Transcranial Direct Current Stimulation Versus Sham in Subacromial Pain Syndrome Experimental Stimulation, Sham Stimulation - Subacromial Pain Syndrome, Transcranial Direct Current Stimulation | Not applicable | Unknown | Universidade Federal do Rio Grande do Norte | 32 | 2024-03-04 | 2024-03-27 |
| High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy Active Comparator: Unilateral real High definition transcranial direct current stimulation, Active Comparator: Bilateral real High definition transcranial direct current stimulation, Sham Comparator: Sham High definition transcranial direct current stimulation - Transcranial Direct Current Stimulation, EEG | Not applicable | Unknown | Anhui Medical University | 90 | 2024-02-12 | 2024-02-20 |
| Impact of Transcranial Direct Current Stimulation on the Capacity to Perform Burpees tDCS targeting DLPFC, tDCS targeting M1, SHAM tDCS - Transcranial Direct Current Stimulation, Dorsolateral Prefrontal Cortex | Not applicable | Completed | Universidad Católica San Antonio de Murcia | 20 | 2024-01-06 | 2024-06-25 |
| The Effects of Two Types of t-DCS Stimulation on Robot-assisted Gait Training in Patients With Multiple Sclerosis Transcutaneous Spinal Direct Current Stimulation and Transcranial Direct Current Stimulation, Sham ts-DCS and sham t-DCS - Multiple Sclerosis, Transcranial Direct Current Stimulation | Not applicable | Unknown | Istanbul Medeniyet University | 36 | 2023-12-20 | 2024-05-20 |
| Effects of Transcutaneous Spinal Direct Current Stimulation on Mobility in Cases With Multiple Sclerosis Transcutaneous Spinal Direct Current Stimulation - Multiple Sclerosis, Transcranial Direct Current Stimulation | Not applicable | Completed | Istanbul Medeniyet University | 22 | 2023-11-27 | 2024-04-18 |
| The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus Receive traditional medical therapy and transcranial direct current stimulation, Receive traditional medical therapy and sham stimulation - Tinnitus, Subjective, Sudden Deafness | Not applicable | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 86 | 2023-11-23 | 2023-11-27 |
| TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals. tdcs lDLPFC, tdcs rVLPFC, Sham - Subthreshold Depression, Young People | Not applicable | Recruiting | Guangzhou Psychiatric Hospital | 150 | 2023-11-01 | 2024-12-12 |
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Stroke (9) · Chronic Pain (4) · Dementia (4) · Depressive Disorder, Major (4) · Pain (4) · Parkinson Disease (4) · Motor Activity (3) · Multiple Sclerosis (3) · Schizophrenia (3) · Alzheimer Disease (2) · Anxiety Disorders (2) · Autism Spectrum Disorder (2) · Child Development Disorders, Pervasive (2) · Cognitive Dysfunction (2) · Communication Disorders (2)
Nervous System Diseases (36) · Mental Disorders (27) · Central Nervous System Diseases (23) · Brain Diseases (22) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (22) · Neurologic Manifestations (20) · Cardiovascular Diseases (10) · Vascular Diseases (10) · Cerebrovascular Disorders (9) · Pain (8) · Neurocognitive Disorders (7) · Neurodevelopmental Disorders (7) · Mood Disorders (6) · Movement Disorders (6)
Transcranial Direct Current Stimulation (55) · Cognitive Remediation (2) · Saline Solution (2) · Speech Therapy (2) · Brain-Computer Interfaces (1) · Cognitive Training (1) · Exercise (1) · Hypnosis (1) · Immobilization (1) · Magnetic Resonance Spectroscopy (1) · Mastication (1) · Mindfulness-Based Stress Reduction (1) · Nutrition Assessment (1) · Occupational Therapy (1) · Physical Therapy Modalities (1)
Anhui Medical University (8) · The Hong Kong Polytechnic University (6) · Hospital de Clinicas de Porto Alegre (5) · Universidade Federal do Rio Grande do Norte (4) · Seoul National University Hospital (3) · Centre for Addiction and Mental Health (2) · Chang Gung Memorial Hospital (2) · China Medical University Hospital (2) · Hôpital le Vinatier (2) · Istanbul Medeniyet University (2) · National Taiwan University Hospital (2) · Peking University First Hospital (2) · Shanghai Mental Health Center (2) · Universidade Federal de Pernambuco (2) · University Hospital Tuebingen (2)
China (22) · Brazil (12) · United States (9) · Hong Kong (6) · Taiwan (6) · Canada (4) · France (4) · South Korea (4) · Spain (4) · Belgium (3) · Germany (3) · Turkey (Türkiye) (3) · Israel (2) · Cyprus (1) · Japan (1)
Wolnei Caumo, PhD (4) · Yvonne Han, PhD (4) · Dong-Xin Wang, MD, PhD (2) · Stephanie Kullmann, PhD (2) · Ting Zhang (2) · Won-Seok Kim, MD, PhD (2) · Andre R Brunoni, PhD (1) · Benyan Luo (1) · Chon-Haw Tsai, PHD (1) · Clarissa Bueno, MD, PhD (1) · Cynthia Conklin, PhD (1) · Fengqiong Yu, MD (1) · Fofi Constantinidou, Ph.D. (1)
PMID 12425704, PMID 15167555, PMID 15324362, PMID 15999258, PMID 17086200, PMID 18717717, PMID 20633376, PMID 21211016, PMID 21825004, PMID 21989847, PMID 22437511, PMID 22532165, PMID 22695026, PMID 23831184, PMID 24166562, PMID 24176927, PMID 24626608, PMID 24992897, PMID 26437233, PMID 26441544, PMID 27185737, PMID 27653887, PMID 27838936, PMID 29681876, PMID 29761128, PMID 31555109, PMID 31849628, PMID 32122766, PMID 32714178, PMID 33175411, PMID 33240121, PMID 33729165, PMID 34630733, PMID 34785366, PMID 34793641, PMID 35181532, PMID 35875789, PMID 36504629, PMID 36718400, PMID 37151094, PMID 37689323, PMID 37938095, PMID 38159941, PMID 38716555, PMID 39250901, PMID 39536019, PMID 39981427, PMID 40033447, PMID 40619473, PMID 40713415
1RF1MH116987-01 (2), R01AG021501 (1), R21DA045137 (1), RF1MH114290 (1)