110 completed, 15 recruiting, 13 terminated, 12 not yet recruiting. 67 Not applicable, 31 Phase 4, 21 Phase 3, 12 Phase 2, 4 Phase 1.
Follow Chlamydiaceae Infections: new trials by email Literature Review of Chlamydiaceae Infections trials Research Report on Chlamydiaceae Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| Outcomes From Point-of-Care Sexually Transmitted Infection (STI) Testing in an Urban Sexual Health Clinic: A Randomized Trial Point-of-care assay for chlamydia and gonorrhea, Laboratory-based chlamydia and gonorrhea NAAT, CRISPR-based assay - Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection | Not applicable | Not yet recruiting | Massachusetts General Hospital | 400 | 2026-11-01 | 2026-10-06 |
| Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment Study Venue-based, peer-enhanced strategy for integrated HIV self-testing (and self-collected STI testing - HIV, Syphilis | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 232 | 2026-10-01 | 2026-09-18 |
| Strengthening, Guidance, Health, Empowerment Self-sampling for six sexually transmitted infections - HIV Infection, Syphilis | Not applicable | Not yet recruiting | University Hospital, Montpellier | 200 | 2026-09-01 | 2026-08-26 |
| Multicentre Study Evaluating the Efficacy of a 7-day Course of Doxycycline for the Treatment of Asymptomatic Anal Lymphogranuloma Venereum. Doxycline - Lymphogranuloma Venereum, no Anorectal Symptoms | Phase 2 | Not yet recruiting | University Hospital, Bordeaux | 120 | 2026-09-01 | 2026-08-17 |
| National Rapid TLC: Testing and Linkage to Care Xpert® HIV-1 Qual XC - HIV, Chlamydia | Not applicable | Not yet recruiting | Unity Health Toronto | 2500 | 2026-08-01 | 2026-07-28 |
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-07-01 | 2026-06-18 |
| Healthy Expectancy Through Routine Antenatal STI Screening Chlamydia trachomatis and Neisseria gonorrhoeae screening - Antenatal Health, Antenatal Care | Not applicable | Recruiting | Adriane Wynn | 2000 | 2026-05-25 | 2026-07-02 |
| Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland HIV (Human Immunodeficiency Virus), Chlamydia | Not yet recruiting | University of Zurich | 1800 | 2026-04-07 | 2026-04-08 | |
| Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling - Gonorrhea, Chlamydia | Phase 4 | Recruiting | Westat | 760 | 2026-02-27 | 2026-10-16 |
| Point of Care STI Testing Gonorrhea/chlamydia Point-of-Care Testing - Point of Care STI Testing | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 6460 | 2026-02-24 | 2026-05-05 |
| Adaptive RCT of Corticosteroids for Severe Chlamydia Psittaci Pneumonia in Adults Saline (0.9%, sterile, for infusion), low dose Methylprednisolone, Moderate dose Methylprednisolone - Psittacosis | Phase 3 | Not yet recruiting | Qingyuan Zhan | 100 | 2026-01-15 | 2026-01-20 |
| RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) B-RAP, BLTR - Trachoma, Eye Diseases | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 1000 | 2026-01-13 | 2026-04-13 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Using Urine to Study Antibodies & Functional Cell-Mediated Immunity in the Context of Chlamydia Trachomatis Sampling - Chlamydia Trachomatis Genital Infection | Recruiting | Universiteit Antwerpen | 73 | 2025-12-10 | 2026-05-19 | |
| Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM WHO-recommended periodic presumptive treatment, Doxycycline post-exposure prophylaxis - Gonorrhea Male, Chlamydia (Male) | Phase 4 | Recruiting | University of Washington | 2900 | 2025-10-29 | 2025-11-19 |
| Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro Doxycycline - Sexually Transmitted Diseases, Syphilis | Not applicable | Recruiting | Oswaldo Cruz Foundation | 200 | 2025-10-28 | 2026-03-30 |
| The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand. Doxycycline (200mg/day) - Syphilis Infection, Gonorrhea | Phase 4 | Recruiting | Bangrak STIs Center | 400 | 2025-10-06 | 2026-02-09 |
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Chlamydia Infections (132) · Gonorrhea (88) · Sexually Transmitted Diseases (46) · Trachoma (38) · Syphilis (30) · HIV Infections (18) · Trichomonas Infections (15) · Acquired Immunodeficiency Syndrome (13) · Infections (7) · Sexual Behavior (7) · Trichiasis (6) · Elephantiasis, Filarial (5) · Vaginosis, Bacterial (5) · Bacterial Infections (4) · Disease (4)
Bacterial Infections and Mycoses (170) · Gram-Negative Bacterial Infections (170) · Bacterial Infections (166) · Infections (163) · Genital Diseases (133) · Urogenital Diseases (133) · Sexually Transmitted Diseases, Bacterial (132) · Communicable Diseases (131) · Neisseriaceae Infections (89) · Sexually Transmitted Diseases (87) · Pathological Conditions, Signs and Symptoms (63) · Pathologic Processes (60) · Disease Attributes (54) · Conjunctival Diseases (40)
Azithromycin (27) · Doxycycline (9) · Ivermectin (4) · Albendazole (3) · Ceftriaxone (3) · HIV Testing (2) · Health (2) · Mass Screening (2) · Methods (2) · Permethrin (2) · Sodium Chloride (2) · Standard of Care (2) · Therapeutics (2) · Water (2) · Amoxicillin (1)
University of California, San Francisco (19) · London School of Hygiene and Tropical Medicine (8) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · Johns Hopkins University (7) · Centers for Disease Control and Prevention (6) · Northwestern University (5) · University of Pittsburgh (5) · National Heart, Lung, and Blood Institute (NHLBI) (4) · Emory University (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (3) · University of California, Los Angeles (3) · University of North Carolina, Chapel Hill (3) · University of Washington (3) · Arkansas Children's Hospital Research Institute (2) · Columbia University (2)
United States (89) · Ethiopia (11) · United Kingdom (9) · Tanzania (6) · Australia (4) · France (4) · Botswana (3) · Canada (3) · Niger (3) · Uganda (3) · Belgium (2) · China (2) · Kenya (2) · Malawi (2) · Mexico (2)
Julius Schachter, PhD (5) · Jim Carey, MPH (3) · Tom Lietman, MD (3) · Brian Mustanski, PhD (2) · Catherine Oldenburg, ScD, MPH (2) · Elodie Lebas, RN (2) · Emily Gower, PhD (2) · Emma Harding-Esch (2) · Jeremy D Keenan, MD, MPH (2) · Jesse L Clark, MD, MSc (2) · Kieran S O'Brien, MPH (2) · Matthew J Burton, PhD FRCOphth (2) · Michael E Newcomb, Ph.D. (2) · Paul Emerson, PhD (2) · Ricky Hill, Ph.D. (2)
PMID 31589610, PMID 21099596, PMID 21775837, PMID 22953007, PMID 37018493, PMID 37351709, PMID 11386956, PMID 11880389, PMID 12392124, PMID 12593898, PMID 12904390, PMID 12958275, PMID 15937765, PMID 16314767, PMID 16314768, PMID 16356945, PMID 16455891, PMID 16825373, PMID 16905024, PMID 17051493, PMID 17077230, PMID 17301105, PMID 17583820, PMID 18038280, PMID 18053199, PMID 18532873, PMID 19023429, PMID 19077198, PMID 19104366, PMID 19220138, PMID 19321868, PMID 19329003, PMID 19389002, PMID 19549331, PMID 19591608, PMID 19616720, PMID 19629306, PMID 19936044, PMID 20155838, PMID 20308834, PMID 20335410, PMID 20370481, PMID 20378636, PMID 20585275, PMID 21072224, PMID 21124216, PMID 21173720, PMID 21216000, PMID 21489882, PMID 21685340
5UG1EY030833 (2), R01AI048789 (2), U19AI084024 (2), 1IK2CX002822-01A1 (1), 1UG1EY028088 (1), 1UG1EY036891 (1), 5UM1AI106707 (1), 5UM1AI148684-03 (1), D43TW009340 (1), K23EY019881 (1), R01AI068107 (1), R01AI143439 (1), R01AI158826 (1), R01AI179838 (1), R01CA321103 (1)