63 completed, 9 withdrawn, 5 recruiting, 5 terminated. 27 Phase 4, 26 Phase 3, 12 Not applicable, 12 Phase 1, 10 Phase 2.
Follow Eye Infections, Bacterial: new trials by email Literature Review of Eye Infections, Bacterial trials Research Report on Eye Infections, Bacterial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-10-05 | 2026-10-30 |
| Safety and Efficacy of SUM-191 for Patients With Bacterial Conjunctivitis SUM-191, Placebo - Bacterial Conjunctivitis | Phase 1 / Phase 2 | Recruiting | Senju USA, Inc. | 426 | 2026-06-25 | 2026-06-30 |
| RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) B-RAP, BLTR - Trachoma, Eye Diseases | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 1000 | 2026-01-13 | 2026-04-13 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis Fusidic Acid 1%, Placebo - Bacterial Conjunctivitis | Phase 3 | Recruiting | Baxis Pharmaceuticals, Inc. | 400 | 2025-03-21 | 2026-03-17 |
| Azithromycin Reduction to Reach Elimination of Trachoma B Azithromycin - Trachoma | Phase 4 | Withdrawn | University of California, San Francisco | 2024-10-01 | 2026-03-13 | |
| Study to Evaluate the Safety and Tolerability of PRO-231 Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects PRO-231, VIGAMOXI® - Ophthalmological Agent Toxicity, Bacterial Conjunctivitis | Phase 1 | Completed | Laboratorios Sophia S.A de C.V. | 37 | 2024-01-30 | 2025-06-15 |
| Development of a Mobile Terminal-Based Intelligent Detection System for Multiple Anterior Segment Diseases of the Eye Smartphone-based on-device artificial intelligence system for anterior segment eye disease screening - Artifical Intelligence, Cataract | Recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 3000 | 2023-12-12 | 2026-06-09 | |
| Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures 0.9% Bacteriostatic Local Anesthetic Injection, 1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection, Eyelid Lesion Removal - Eyelid Tumor, Eyelid Bump | Phase 4 | Completed | University of California, San Francisco | 95 | 2022-05-17 | 2025-07-08 |
| Enhancing the A in SAFE for Trachoma Azithromycin for Routine Community-wide MDA, Two Additional Rounds of Azithromycin for Children, Azithromycin for Second Community-wide MDA - Trachoma | Phase 4 | Completed | Emory University | 34630 | 2022-05-04 | 2024-02-29 |
| Kebele Elimination of Trachoma for Ocular Health Azithromycin - Trachoma | Phase 4 | Active not recruiting | University of California, San Francisco | 320000 | 2022-02-07 | 2025-10-23 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Assessment of the Effects and Tolerability of RD03/2016 for the Treatment of Bacterial Conjunctivitis in Adults RD03/2016 eye drops, Levofloxacin 0.5% eye drops solution (Oftaquix®) - Conjunctivitis, Bacterial | Phase 2 | Completed | NTC srl | 252 | 2021-11-05 | 2024-09-27 |
| Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine Betadine, Avenova - Eye Infections, Bacterial | Phase 4 | Suspended | University of Miami | 230 | 2021-08-06 | 2025-07-10 |
| Azithromycin Reduction to Reach Elimination of Trachoma Azithromycin - Trachoma | Phase 4 | Completed | University of California, San Francisco | 3931 | 2021-05-29 | 2026-03-25 |
| Safety and Immunogenicity of a Chlamydia Vaccine CTH522 CTH522-CAF01 IM, CTH522-CAF09b IM, CTH522 ID - Trachoma | Phase 1 | Completed | Statens Serum Institut | 65 | 2020-02-17 | 2024-08-22 |
| Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry - Dry Eye Syndrome, Infectious Keratoconjunctivitis | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 300 | 2020-02-01 | 2026-04-27 | |
| Smartphone App for Taking Images of Conjunctivae TOFTEE - Trachoma | Not applicable | Terminated | London School of Hygiene and Tropical Medicine | 125 | 2019-07-08 | 2022-08-22 |
| App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders Inter-grader agreement (IGA) app - Trachoma | Not applicable | Terminated | London School of Hygiene and Tropical Medicine | 32 | 2019-07-08 | 2022-08-22 |
| Microbiologic Alterations of the Conjunctiva of Hot Tub-soaking Ophthalmologists Dunk, Exposure to Hot Tub - Conjunctivitis, Bacterial, Keratitis Bacterial | Not applicable | Completed | University of California, San Francisco | 36 | 2019-05-27 | 2020-09-10 |
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Trachoma (38) · Conjunctivitis, Bacterial (35) · Conjunctivitis (8) · Chlamydia Infections (7) · Bacterial Infections (6) · Trichiasis (6) · Eye Diseases (5) · Elephantiasis, Filarial (4) · Hordeolum (4) · Eye Infections (3) · Infections (3) · Blepharitis (2) · Cataract (2) · Keratitis (2)
Bacterial Infections and Mycoses (88) · Eye Infections (85) · Infections (85) · Eye Diseases (83) · Bacterial Infections (82) · Conjunctival Diseases (77) · Conjunctivitis (70) · Conjunctivitis, Bacterial (41) · Corneal Diseases (41) · Gram-Negative Bacterial Infections (41) · Chlamydiaceae Infections (40) · Chlamydia Infections (33) · Eyelid Diseases (11) · Communicable Diseases (7)
Azithromycin (29) · Moxifloxacin (7) · Gatifloxacin (6) · Ophthalmic Solutions (6) · besifloxacin (6) · Ivermectin (4) · Albendazole (3) · Lubricant Eye Drops (2) · Permethrin (2) · Water (2) · pazufloxacin (2) · Adrenal Cortex Hormones (1) · Alkalies (1) · Amoxicillin (1) · Amyloid (1)
University of California, San Francisco (15) · Alcon Research (7) · Bausch & Lomb Incorporated (7) · Johns Hopkins University (7) · Laboratoires Thea (7) · London School of Hygiene and Tropical Medicine (7) · Laboratorios Sophia S.A de C.V. (5) · Allergan (3) · Emory University (3) · Merck Sharp & Dohme LLC (2) · Adapt Produtos Oftalmológicos Ltda. (1) · Azidus Brasil (1) · Baskent University (1) · Baxis Pharmaceuticals, Inc. (1) · Beijing Tongren Hospital (1)
United States (37) · Ethiopia (11) · Mexico (5) · Tanzania (5) · United Kingdom (5) · Canada (3) · China (3) · France (3) · Niger (3) · Brazil (2) · India (2) · Italy (2) · Poland (2) · Spain (2) · Australia (1)
Tom Lietman, MD (3) · Catherine Oldenburg, ScD, MPH (2) · Elodie Lebas, RN (2) · Emily Gower, PhD (2) · Emma Harding-Esch (2) · Jeremy D Keenan, MD, MPH (2) · Johnson Varughese (2) · Julius Schachter, PhD (2) · Kieran S O'Brien, MPH (2) · Matthew J Burton, PhD FRCOphth (2) · Paul Emerson, PhD (2)
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