10 completed, 1 recruiting, 1 unknown, 1 withdrawn. 10 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 7, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow Trichiasis: new trials by email Literature Review of Trichiasis trials Research Report on Trichiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) B-RAP, BLTR - Trachoma, Eye Diseases | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 1000 | 2026-01-13 | 2026-04-13 |
| FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial Fluorometholone 0.1% Oph Susp, Artificial Tears - Trachomatous Trichiasis (TT), Eye Diseases | Phase 3 | Completed | Massachusetts Eye and Ear Infirmary | 2410 | 2021-08-19 | 2026-03-24 |
| Histology Evaluation of Radiofrequency Ablation Radiofrequency ablation - Trichiasis | Not applicable | Withdrawn | Ochsner Health System | 2019-07-02 | 2023-04-25 | |
| Repeat Surgery for Patients With Post-operative Trachomatous Trichiasis Trial BRAP (Bevel/rotate/advance procedure), Trabut - Trichiasis, Surgery | Not applicable | Completed | University of North Carolina, Chapel Hill | 886 | 2019-04-13 | 2024-02-22 |
| The Effect of Long-Term HEAD START Training on Surgical Skill Levels Long-Term HEAD START Training, Standard of Care - Trichiasis, Surgery | Not applicable | Completed | University of North Carolina, Chapel Hill | 30 | 2017-05-17 | 2018-03-15 |
| Maximizing Trichiasis Surgery Success Bilamellar 3 mm, Bilamellar 5 mm, Trabut 3 mm - Trichiasis, Surgery | Not applicable | Completed | University of North Carolina, Chapel Hill | 4914 | 2017-04-05 | 2023-12-05 |
| Fluorometholone as Ancillary Therapy for TT Surgery Fluorometholone 0.1% ophthalmic solution, Artificial tears (Placebo) - Trichiasis, Trachoma | Not applicable | Completed | University of Pennsylvania | 154 | 2013-11-01 | 2016-04-21 |
| Identification of TT Cases by Community Treatment Assistants: An Assessment TT Training Program and TT Screening Card - Trichiasis | Not applicable | Completed | Johns Hopkins University | 27473 | 2013-02-01 | 2018-03-21 |
| Modified Instrumentation for Surgery to Correct Trichiasis TT Clamp, Standard BLTR Technique - Trachoma | Not applicable | Completed | Johns Hopkins University | 1927 | 2009-05-01 | 2017-05-19 |
| Comparison of Argon Laser and Radiofrequency in Trichiasis Treatment argon laser and radiofrequency - Trichiasis | Not applicable | Unknown | Shahid Beheshti University of Medical Sciences | 2008-10-01 | 2008-10-21 | |
| A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery Trichiasis surgery with absorbable sutures, Trichiasis surgery with non-absorbable sutures - Trachomatous Trichiasis, Trachoma | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 1300 | 2008-03-01 | 2012-01-12 |
| A Trial of Epilation Verses Surgery for Minor Trichiasis Trichiasis surgery, Epilation - Trachomatous Trichiasis | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 1300 | 2008-03-01 | 2012-01-12 |
| Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia azithromycin, topical tetracycline - Trichiasis | Phase 4 | Completed | Johns Hopkins University | 1452 | 2001-08-01 | 2017-08-07 |
Trachoma (6) · Eye Diseases (2) · Eyelid Diseases (1)
Eyelid Diseases (12) · Eye Diseases (11) · Bacterial Infections (6) · Bacterial Infections and Mycoses (6) · Chlamydia Infections (6) · Chlamydiaceae Infections (6) · Conjunctival Diseases (6) · Conjunctivitis (6) · Conjunctivitis, Bacterial (6) · Corneal Diseases (6) · Eye Infections (6) · Eye Infections, Bacterial (6) · Gram-Negative Bacterial Infections (6) · Infections (6)
Fluorometholone (2) · Lubricant Eye Drops (2) · Azithromycin (1) · Hair Removal (1) · Inosine Monophosphate (1) · Lasers, Gas (1) · Ophthalmic Solutions (1) · Radiofrequency Ablation (1) · Standard of Care (1) · Tetracycline (1)
University of North Carolina, Chapel Hill (4) · Johns Hopkins University (3) · London School of Hygiene and Tropical Medicine (2) · Massachusetts Eye and Ear Infirmary (1) · Ochsner Health System (1) · Shahid Beheshti University of Medical Sciences (1) · University of Pennsylvania (1)
Ethiopia (7) · United States (4) · Iran (1) · Tanzania (1)
Emily Gower, PhD (4) · Matthew J Burton, PhD FRCOphth (2) · Emily W Gower (1) · Jayne Weiss, MD (1) · John H Kempen, MD MPH MHS PhD (1) · John H Kempen, MD MPH PhD (1) · Priya Sahu, MD (1) · Sheila K West (1) · Sheila K West, PhD (1) · Wondu Alemayehu, MD, MPH (1)
PMID 31589610, PMID 22953007, PMID 16534049, PMID 19901217, PMID 21051704, PMID 22159169, PMID 22180731, PMID 22180732, PMID 23494035, PMID 32193277, PMID 37757880, PMID 39006430, PMID 39226693, PMID 39656933, PMID 40737343, PMID 41539314
1UG1EY036891 (1), UG1EY025992 (1), UG1EY025992-04S1 (1)