Community-based Mobile-assisted Brief Intervention for Smoking Cessation

NCT07375459 — Not applicable, Active not recruiting, 100 participants, National University of Singapore

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Mobile-assisted Brief Intervention for Smoking Cessation in Community-based Setting: a Pilot Randomised Controlled Trial

Registry	NCT07375459
Status	Active not recruiting
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: none, treatment
Enrollment	100 (Estimated)
Sponsor	National University of Singapore (Other)
Conditions	Smoking &Amp; Tobacco Cessation
Interventions	Brief cessation advice + self-help booklet, Opt-out referral, Mobile chat messaging (Behavioral)
Dates	start 2026-02-04, primary completion 2026-12-31 (estimated), completion 2027-03-31 (estimated), first posted 2026-01-29, last updated 2026-07-16
Locations	1 site in Singapore

-Summary

The goal of this pilot trial is to evaluate the feasibility of a mobile-assisted brief intervention for smoking cessation in community-based individuals in Singapore. Specific aims include:

1. To assess how many eligible individuals accept the invitation to participate in the trial
2. To assess the retention of the participants through 6 months after treatment initiation
3. To assess the acceptability of the intervention in terms of participants' engagement and ratings
4. To examine the intervention effect on abstinence outcomes

Participants will be randomly assigned to either the intervention group or control group and followed for 6 months from randomisation.

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+Arms and interventions

Arm	Type	Interventions	Description
Mobile-assisted brief intervention	Experimental	Behavioral: Brief cessation advice + self-help booklet; Behavioral: Opt-out referral; Behavioral: Mobile chat messaging
Brief advice	Active comparator	Behavioral: Brief cessation advice + self-help booklet

Brief cessation advice + self-help booklet (Behavioral): Participants will receive brief cessation advice following the AWARD (ask, warn, advise, refer, do-it-again) model and a 24-page self-help booklet.
Opt-out referral (Behavioral): Research personnel will assist the participant in signing up for the I Quit Programme to receive additional cessation support, unless they decline
Mobile chat messaging (Behavioral): Participants will receive personalised chat-based support delivered by a live counsellor for 3 months via WhatsApp. The message will incorporate behaviour change techniques for smoking cessation and mindfulness principles to strengthen participants' capacity to quit smoking.

+Outcome measures

Primary outcomes

Biochemically validated smoking abstinence rate [6 months]: Defined as an exhaled carbon monoxide level of <5 parts per million or a negative salivary cotinine test (cut off 30ng/mL)
Recruitment rate [6 months]: Number of participants divided by the number of eligible subjects
Retention rate [6 months]: Number of participants completed the follow-up divided by the number of participants

Secondary outcomes

Self-reported 7-day point-prevalence smoking abstinence rate [3 months]: Being completely smoke-free in the past 7 days
Self-reported 7-day point-prevalence smoking abstinence rate [6 months]: Being completely smoke-free in the past 7 days
Self-reported smoking reduction rate [3 months]: Smoking reduction by at least half of the baseline daily number of cigarettes in individuals who continue to smoke
Self-reported smoking reduction rate [6 months]: Smoking reduction by at least half of the baseline daily number of cigarettes in individuals who continue to smoke
Self-reported quit attempt rate [3 months]: Serious quit attempt that lasted 24 hours or longer
Self-reported quit attempt rate [6 months]: Serious quit attempt that lasted 24 hours or longer
Smoking cessation service use rate [3 months]: Use of any smoking cessation service during the follow-up period
Smoking cessation service use rate [6 months]: Use of any smoking cessation service during the follow-up period

+Eligibility

Sex: All, ages: 21 Years to 80 Years, accepts healthy volunteers

Inclusion Criteria:

* Aged 21 to 80 years
* Smoked at least one cigarette daily
* Able to communicate and read in English or Chinese
* Own a smartphone with WhatsApp installed

Exclusion Criteria:

* Exposed to any smoking cessation treatment in the past 3 months
* Pregnant women

+Locations (1)

Facility	City	Country	Status
National University of Singapore	Singapore	Singapore

+Investigators

Tzu Tsun Luk, PhD, RN, Principal investigator, National University of Singapore