14 completed. 14 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 14 |
| Phase 2 | 3 | Completed 3 |
Follow Tinnitus: new trials by email Literature Review of Tinnitus trials Research Report on Tinnitus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SPI-1005 for the Treatment of Meniere's Disease Ebselen, Placebo - Meniere Disease, Ménière | Phase 3 | Completed | Sound Pharmaceuticals, Incorporated | 220 | 2022-08-02 | 2026-07-23 |
| AM-101 in the Treatment of Post-Acute Tinnitus 1 AM-101 - Tinnitus | Phase 3 | Completed | Auris Medical, Inc. | 260 | 2014-06-01 | 2018-05-16 |
| AM-101 in the Treatment of Post-Acute Tinnitus 2 AM-101 - Tinnitus | Phase 3 | Completed | Auris Medical AG | 487 | 2014-06-01 | 2023-09-14 |
| AM-101 in the Treatment of Acute Tinnitus 2 AM-101, Placebo - Tinnitus | Phase 3 | Completed | Auris Medical, Inc. | 343 | 2014-02-01 | 2018-05-29 |
| AM-101 in the Treatment of Acute Tinnitus 3 AM-101, Placebo - Tinnitus | Phase 3 | Completed | Auris Medical AG | 893 | 2014-01-01 | 2023-09-14 |
| Evaluation of the CR Neuromodulation Treatment for Tinnitus CR Neuromodulation, Tinnitus masking - Tinnitus | Phase 2 / Phase 3 | Completed | Nottingham University Hospitals NHS Trust | 100 | 2012-08-01 | 2016-08-22 |
| Cognitive Training for Firefighters With Tinnitus Brain Fitness Program - Tinnitus - Tinnitus | Phase 3 | Completed | Washington University School of Medicine | 60 | 2012-03-01 | 2014-05-09 |
| Tinnitus Retraining Therapy Trial Conventional sound generator (SG), Placebo sound generator (placebo SG), Standard of Care (SC) - Subjective Tinnitus | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 151 | 2011-07-01 | 2018-11-21 |
| A Trial of Magnesium Dependent Tinnitus Magnesium, Placebo - Tinnitus | Phase 3 | Completed | Mayo Clinic | 38 | 2011-07-01 | 2015-04-30 |
| Idiopathic Intracranial Hypertension Treatment Trial Acetazolamide, Placebo, Formal weight loss counselling program - Idiopathic Intracranial Hypertension | Phase 2 / Phase 3 | Completed | St. Luke's-Roosevelt Hospital Center | 165 | 2010-01-01 | 2018-12-12 |
| Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus Neramexane mesylate, Placebo - Subjective Tinnitus | Phase 3 | Completed | Merz Pharmaceuticals GmbH | 455 | 2009-09-01 | 2012-11-28 |
| Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus Neramexane mesylate, Placebo - Subjective Tinnitus | Phase 3 | Completed | Merz Pharmaceuticals GmbH | 400 | 2008-11-01 | 2010-07-01 |
| Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus Neramexane mesylate, Placebo - Subjective Tinnitus | Phase 3 | Completed | Merz Pharmaceuticals GmbH | 411 | 2008-09-01 | 2016-02-04 |
| Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus significant chronic primary auditory cortex stimulation during the first two weeks, non significant chronic primary auditory cortex stimulation during the first two weeks - Hearing Disorders, Hearing Loss | Phase 2 / Phase 3 | Completed | University Hospital, Bordeaux | 10 | 2007-06-01 | 2011-01-28 |
Hearing Loss (2) · Diplopia (1) · Dizziness (1) · Headache (1) · Hearing Disorders (1) · Hyperacusis (1) · Meniere Disease (1) · Obesity (1) · Papilledema (1) · Pseudotumor Cerebri (1) · Vertigo (1) · Vision Disorders (1)
Ear Diseases (14) · Nervous System Diseases (14) · Neurologic Manifestations (14) · Otorhinolaryngologic Diseases (14) · Pathological Conditions, Signs and Symptoms (14) · Sensation Disorders (14) · Signs and Symptoms (14) · Hearing Disorders (13) · Body Weight (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cranial Nerve Diseases (1) · Endolymphatic Hydrops (1) · Eye Diseases (1) · Intracranial Hypertension (1)
PDCD5 protein, rat (4) · Acetaminophen (1) · Acetazolamide (1) · Aspirin (1) · Codeine (1) · Directive Counseling (1) · Ibuprofen (1) · Magnesium (1) · Naproxen (1) · Standard of Care (1) · butalbital (1) · ebselen (1)
Merz Pharmaceuticals GmbH (3) · Auris Medical AG (2) · Auris Medical, Inc. (2) · Johns Hopkins Bloomberg School of Public Health (1) · Mayo Clinic (1) · Nottingham University Hospitals NHS Trust (1) · Sound Pharmaceuticals, Incorporated (1) · St. Luke's-Roosevelt Hospital Center (1) · University Hospital, Bordeaux (1) · Washington University School of Medicine (1)
United States (8) · Germany (4) · Austria (2) · France (2) · United Kingdom (2) · Belgium (1) · Brazil (1) · Canada (1) · Czechia (1) · Mexico (1) · Netherlands (1) · Poland (1) · Portugal (1) · South Africa (1) · Spain (1)
C. Craig Formby, PhD (1) · David McAlpine, PhD (1) · Deborah A Hall, PhD (1) · Derek J Hoare, PhD (1) · Emmanuel Cuny, MD (1) · Jay F Piccirillo, MD (1) · Michael Cevette, PhD (1) · Michael Wall, MD (1) · Roberta W Scherer, PhD (1)
PMID 24756302, PMID 24756514, PMID 24781936, PMID 25017670, PMID 25370510, PMID 25370513, PMID 26024112, PMID 26335066, PMID 26618282, PMID 26778344, PMID 26934136, PMID 27694262, PMID 28114646, PMID 28130349, PMID 28492874, PMID 28608739, PMID 29792074, PMID 31120533, PMID 32703244, PMID 35073492, PMID 35326273
2009 (1), U01DC007422 (1), U10EY017281 (1), U10EY017387 (1)