38 completed, 14 unknown, 9 terminated, 6 recruiting. 24 Not applicable, 16 Phase 2, 13 Phase 3, 9 Phase 4, 7 Phase 1.
Follow Meniere Disease: new trials by email Literature Review of Meniere Disease trials Research Report on Meniere Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SPI-1005 for the Treatment of Meniere's Disease (Open Label) Ebselen - Meniere's Disease, Ménière's Disease | Phase 3 | Active not recruiting | Sound Pharmaceuticals, Incorporated | 200 | 2025-10-29 | 2026-07-13 |
| Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere's Disease Vestibular Rehabilitation + Cervical Mobilization, vestibular rehabilitation - Meniere Disease | Not applicable | Completed | Abant Izzet Baysal University | 48 | 2025-09-20 | 2026-10-06 |
| Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes a blood withdrawal will be obtained, blood withdrawal - Vertigo, Meniere's Disease | Recruiting | IRCCS San Raffaele | 250 | 2025-04-09 | 2026-04-08 | |
| Sleep Disorders and Their Impact on Patients With Ménière's Disease Sleep Disorders | Recruiting | University Hospital, Strasbourg, France | 100 | 2024-07-19 | 2025-12-23 | |
| Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention - Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo | Not applicable | Unknown | University of British Columbia | 50 | 2024-06-01 | 2024-08-15 |
| The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease Methylprednisolon, Placebo - Meniere Disease | Phase 3 | Recruiting | Leiden University Medical Center | 148 | 2023-10-01 | 2023-12-04 |
| Modulating Auditory Symptoms and Vertigo of Meniere's Disease by Non-invasive Mastoid Electric Stimulation YPS-201b, betahistine - Meniere's Disease | Phase 1 / Phase 2 | Unknown | Seoul National University Hospital | 120 | 2023-09-18 | 2024-12-05 |
| Imaging of Endolymphatic Hydrops at 7T MRI Meniere Disease | Unknown | King's College Hospital NHS Trust | 16 | 2023-07-01 | 2024-03-06 | |
| Comprehensive Evaluation in Patients With Meniere's Disease Case report form, Tinnitus disability scale, A feeling of fullness and/or pressure in the ear - Meniere Disease, Psychosocial Problem | Completed | Hacettepe University | 34 | 2023-05-15 | 2023-10-13 | |
| Treating the Symptoms of Vertigo in a Real-world Setting Using the OtoBand Otoband Experimental, Otoband Sham - Vertigo, BPPV | Not applicable | Completed | Otolith Labs | 109 | 2023-02-02 | 2025-03-20 |
| Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's Disease APSLXR - Meniere Disease, Vertigo | Phase 1 | Withdrawn | Apsen Farmaceutica S.A. | 2023-01-01 | 2026-09-08 | |
| Meniere Disease and Hearing Aids Hearing aids fitting - Meniere Disease, Hearing Loss, Sensorineural | Not applicable | Unknown | University Hospital, Grenoble | 10 | 2022-11-15 | 2022-10-17 |
| Menier's Disease - Bone Density Study vitamin D plasma levels baseline, Dual-energy X-ray absorptiometry at baseline, cervical Vestibular evoked myogenic potentials at baseline - Meniere Disease, Osteoporosis | Not applicable | Not yet recruiting | HaEmek Medical Center, Israel | 60 | 2022-10-01 | 2022-08-03 |
| SPI-1005 for the Treatment of Meniere's Disease Ebselen, Placebo - Meniere Disease, Ménière | Phase 3 | Completed | Sound Pharmaceuticals, Incorporated | 220 | 2022-08-02 | 2026-07-23 |
| Treatment of Meniere's Disease With Migraine Medications nortriptyline + topiramate - Ménière | Phase 4 | Recruiting | University of California, Irvine | 40 | 2022-08-01 | 2026-06-22 |
| The CAVA Multicentre Dizziness Trial The continuous ambulatory vestibular assessment (CAVA) system - Ménière's Disease, Vestibular Migraine | Not applicable | Completed | Norfolk and Norwich University Hospitals NHS Foundation Trust | 4 | 2022-04-01 | 2026-06-08 |
| Ventilation Tube Insertion for Unilateral Menière's Disease Transmyringeal ventilation tube insertion, Sham-treatment - Meniere Disease | Not applicable | Unknown | Casper Grønlund Larsen | 104 | 2021-09-20 | 2021-10-14 |
| Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome | Recruiting | National Institute on Deafness and Other Communication Disorders (NIDCD) | 210 | 2021-08-17 | 2026-06-29 | |
| Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection Tetracaine 5% drops, Phenol 90% concentration - Intratympanic Steroid Injection, Idiopathic Sudden Sensorineural Hearing Loss | Early Phase 1 | Unknown | Our Lady of the Lake Hospital | 80 | 2021-08-01 | 2023-10-31 |
| Acceleration of the Kinetics of Diffusion of Gadolinium in the Perilymphatic Structures of the Inner Ear. Magnetic Resonance Imaging with Single dose of gadobutrol (Gd-DO3A-butrol, Gadovist® 0.1 mmol/kg, 1 mmol/mL) - Inner Ear ; Meniere's Disease; Imaging | Not applicable | Unknown | University Hospital, Grenoble | 80 | 2021-07-31 | 2021-07-02 |
Showing 20 of 74. Sign in to see all of them.
Vertigo (23) · Hearing Loss (10) · Tinnitus (10) · Dizziness (7) · Hearing Loss, Sudden (6) · Benign Paroxysmal Positional Vertigo (5) · Vestibular Diseases (4) · Vestibular Neuronitis (4) · Endolymphatic Hydrops (3) · Labyrinth Diseases (3) · Diabetes Insipidus (2) · Diabetes Insipidus, Nephrogenic (2) · Hearing Loss, Sensorineural (2) · Labyrinthitis (2)
Ear Diseases (73) · Otorhinolaryngologic Diseases (73) · Endolymphatic Hydrops (71) · Labyrinth Diseases (71) · Nervous System Diseases (40) · Neurologic Manifestations (38) · Pathological Conditions, Signs and Symptoms (38) · Signs and Symptoms (38) · Vestibular Diseases (24) · Sensation Disorders (22) · Hearing Disorders (18) · Cranial Nerve Diseases (6) · Hearing Loss (6) · Retrocochlear Diseases (6) · Vestibulocochlear Nerve Diseases (6)
Betahistine (6) · ebselen (5) · Cochlear Implants (2) · Gadolinium DTPA (2) · Interleukin 1 Receptor Antagonist Protein (2) · Lamotrigine (2) · Methylprednisolone (2) · Steroids (2) · Vestibular Evoked Myogenic Potentials (2) · microcrystalline cellulose (2) · Absorptiometry, Photon (1) · Acyclovir (1) · Audiometry (1) · BID protein, human (1) · Bupropion (1)
Otonomy, Inc. (9) · Sound Pharmaceuticals, Incorporated (5) · Beijing Tongren Hospital (4) · University Hospital, Grenoble (4) · Norfolk and Norwich University Hospitals NHS Foundation Trust (3) · Osaka University (3) · Otolith Labs (3) · Dent Neuroscience Research Center (2) · Seoul National University Hospital (2) · Abant Izzet Baysal University (1) · Abbott (1) · Alvogen Korea (1) · Andrea Vambutas (1) · Apsen Farmaceutica S.A. (1) · Beijing Administration of Traditional Chinese Medicine Bureau (1)
United States (29) · United Kingdom (7) · China (5) · France (5) · Germany (3) · Italy (3) · Japan (3) · Turkey (Türkiye) (3) · Canada (2) · Russia (2) · South Korea (2) · Australia (1) · Belgium (1) · Denmark (1) · Egypt (1)
Kathie Bishop, PhD (5) · Carl LeBel, PhD (3) · Didier Depireux, PhD (3) · Tadashi Kitahara, M.D.,Ph.D. (3) · Andrea Vambutas, MD (2) · John Phillips, Consultant (2) · Jonathan Kil, MD (2) · Lixin Zhang, MD, PhD (2) · Adolfo M Bronstein, PhD, FRCP (1) · Anna Bedenko, PhD student (1) · Desmond A Nunez, MD, MBA (1) · Eike Krause, MD (1)
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R33DC011827 (2)