4 completed, 2 terminated, 2 withdrawn, 1 not yet recruiting. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 4, Terminated 2, Withdrawn 2, Not yet recruiting 1, Recruiting 1 |
Follow Tibial Fractures: new trials by email Literature Review of Tibial Fractures trials Research Report on Tibial Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Local Anesthetic for Plateau Fractures Bupivacaine injection, Saline - Tibial Plateau Fractures | Phase 4 | Not yet recruiting | University of Washington | 100 | 2024-08-01 | 2024-06-26 |
| Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial Antibiotic coated intramedullary Nail, Standard Intramedullary Nail - Osteomyelitis Tibia, Tibial Fractures | Phase 4 | Recruiting | Wake Forest University Health Sciences | 242 | 2023-05-15 | 2026-08-18 |
| Duloxetine Tibial Plateau Duloxetine, Placebo, Standard of care (SOC) for tibial plateau surgery - Tibial Plateau Fracture, Pain, Postoperative | Phase 4 | Withdrawn | Boston Medical Center | 2022-10-01 | 2022-11-21 | |
| CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF CBD, Placebo - Ankle Fractures, Tibia Fracture | Phase 4 | Withdrawn | NYU Langone Health | 2021-10-01 | 2022-01-28 | |
| Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures Intravenous ketorolac and oral acetaminophen, Intravenous morphine and oral oxycodone - Femur Fracture, Tibial Fractures | Phase 4 | Completed | University of Puerto Rico | 167 | 2021-04-18 | 2025-03-04 |
| Intra-articular Local Anesthetic Injection and Hematoma Aspiration Aspiration, Bupivacaine - Tibial Fractures | Phase 4 | Terminated | Loyola University | 2 | 2016-06-15 | 2018-08-17 |
| rhBMP-2 Versus Autograft in Critical Size Tibial Defects recombinant bone morphogenetic protein 2, Autogenous iliac crest bone graft - Tibial Fractures | Phase 4 | Terminated | St. Louis University | 33 | 2011-08-01 | 2018-10-25 |
| Efficacy Study of Surgical Technique in Intramedullary Tibia Nailing, Using Trigen META Tibia Nails Semi-extended Surgical Technique, Standard Surgical Technique - Tibial Fractures | Phase 4 | Completed | Smith & Nephew Orthopaedics AG | 95 | 2011-02-01 | 2016-06-17 |
| Study Evaluating InductOs in Diaphyseal Tibia Fractures InductOs - Tibial Fractures | Phase 4 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 277 | 2003-09-01 | 2009-09-07 |
| The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial Low Molecular Weight Heparin (dalteparin) - Deep Vein Thrombosis, Pulmonary Embolism | Phase 4 | Completed | Sunnybrook Health Sciences Centre | 700 | 2002-08-01 | 2007-02-27 |
Pain, Postoperative (2) · Tibial Plateau Fractures (2) · Ankle Fractures (1) · Femoral Fractures (1) · Pain (1) · Pulmonary Embolism (1) · Thrombosis (1) · Venous Thrombosis (1)
Fractures, Bone (10) · Leg Injuries (10) · Wounds and Injuries (10) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Knee Fractures (2) · Knee Injuries (2) · Pain (2) · Pathologic Processes (2) · Postoperative Complications (2) · Ankle Injuries (1) · Cardiovascular Diseases (1) · Embolism (1)
Bupivacaine (2) · Acetaminophen (1) · Bone Morphogenetic Protein 2 (1) · Dalteparin (1) · Duloxetine Hydrochloride (1) · Heparin, Low-Molecular-Weight (1) · Oxycodone (1) · Sodium Chloride (1) · Standard of Care (1) · Sugars (1)
Boston Medical Center (1) · Loyola University (1) · NYU Langone Health (1) · Smith & Nephew Orthopaedics AG (1) · St. Louis University (1) · Sunnybrook Health Sciences Centre (1) · University of Puerto Rico (1) · University of Washington (1) · Wake Forest University Health Sciences (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
United States (5) · Germany (2) · Spain (2) · United Kingdom (2) · Belgium (1) · Canada (1) · Finland (1) · France (1) · Italy (1) · Netherlands (1) · Norway (1) · Poland (1) · Puerto Rico (1) · Romania (1) · South Africa (1)
Alan Johnstone, Professor (1) · Daren Forward, MA, FRCS, DM (1) · Ismael Escriba, Dr. (1) · Jonah Hebert-Davies (1) · Joseph Hsu, MD (1) · Luis F. Lojo-Sojo, MD (1) · Markus Graf, Dr. (1) · Paul Tornetta, MD (1) · Pedro Caba, Dr. (1) · Philipp Leucht, MD (1) · Rita Selby, MBBS, FRCPC (1) · Seroos Salavati, MD (1) · Thomas Revak, DO (1)
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