67 unknown. 67 Phase 2, 17 Phase 1, 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 67 | Unknown 67 |
| Phase 1 | 17 | Unknown 17 |
| Phase 3 | 6 | Unknown 6 |
Follow Tauopathies: new trials by email Literature Review of Tauopathies trials Research Report on Tauopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy, Safety and Response Predictors of Astragalus Membranaceus on the Improvement of Cognitive Function in Mild-to-Moderate Alzheimer's Disease 10g Astragalus, Routine treatment, 20g Astragalus - Alzheimer's Disease | Phase 2 | Unknown | Fujian Medical University Union Hospital | 66 | 2024-05-01 | 2024-07-03 |
| Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension Routine treatment, add-on low dose Astragalus, add-on high dose Astragalus - Orthostatic Hypotension, Alzheimer Disease | Phase 2 | Unknown | Fujian Medical University Union Hospital | 66 | 2024-02-20 | 2024-01-05 |
| Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease APH-1105, Placebo - Dementia, Alzheimer Disease 1 | Phase 2 | Unknown | Aphios | 60 | 2023-06-01 | 2021-07-27 |
| Tdap and Biomarkers of Alzheimer's Disease tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine - Alzheimer Disease, Late Onset | Phase 1 / Phase 2 | Unknown | Mindful Diagnostics and Therapeutics, LLC | 50 | 2023-05-01 | 2022-08-25 |
| Protecting Alzheimer Caregivers Using Technology Through Staying Sharp Staying Sharp intervention - Mild Cognitive Impairment, Dementia Alzheimers | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 138 | 2023-04-30 | 2023-02-09 |
| Systemic and Central Inflammation in AD 11C-ER176 - Alzheimer Disease | Phase 2 | Unknown | The Methodist Hospital Research Institute | 40 | 2023-03-17 | 2024-04-25 |
| Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease AstroStem, Placebo - Alzheimer Disease | Phase 2 | Unknown | Nature Cell Co. Ltd. | 100 | 2023-02-01 | 2022-09-28 |
| A 6-Month Study to Evaluate the Safety & Potential Efficacy of Trappsol Cyclo in Patients With Early Alzheimer's Disease Hydroxypropyl Beta Cyclodextrin, Placebo - Alzheimer's Disease | Phase 2 | Unknown | Cyclo Therapeutics, Inc. | 90 | 2022-09-23 | 2023-04-25 |
| Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease smart soup, Donepezil, Memantine - Alzheimer Disease, Mild Cognitive Impairment | Phase 2 | Unknown | Peking Union Medical College Hospital | 180 | 2022-06-01 | 2022-09-14 |
| MW150 Stress Kinase Inhibitor in Mild to Moderate Alzheimer's Disease MW150, Placebo - Alzheimer Disease | Phase 2 | Unknown | Neurokine Therapeutics | 24 | 2022-05-01 | 2022-03-29 |
| Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects [18F]APN-1607 - Alzheimer's Disease, Mild Cognitive Impairment Due to Alzheimer's Disease | Phase 2 | Unknown | APRINOIA Therapeutics, LLC | 130 | 2022-03-22 | 2023-06-15 |
| [18F]MC225-PET in Neurodegenerative Disease [18F]MC225 - Neurodegenerative Diseases, Alzheimer Disease | Phase 1 / Phase 2 | Unknown | University Medical Center Groningen | 30 | 2022-02-01 | 2023-05-10 |
| Phase II Clinical Trial of Interleukin-2 in AD Interleukin-2, Placebo - Alzheimer Disease | Phase 2 | Unknown | The Methodist Hospital Research Institute | 40 | 2022-01-01 | 2024-05-23 |
| SCI-110 for Alzheimer Disease and Agitation SCI -110 - Alzheimer Disease | Phase 2 | Unknown | The Israeli Medical Center for Alzheimer's | 20 | 2021-12-29 | 2022-02-14 |
| Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease COT, Sham - Mild Cognitive Impairment, Early Alzheimer's Disease | Phase 2 | Unknown | Evon Medics LLC | 200 | 2021-11-15 | 2022-05-17 |
| Efficacy and Safety of Yangxue Qingnao Pills in the Treatment of Mild to Moderate Alzheimer's Disease Yangxue Qingnao pills, Placebo - Alzheimer Disease, Yangxue Qingnao Pills | Phase 2 | Unknown | Dongzhimen Hospital, Beijing | 216 | 2021-11-09 | 2023-02-21 |
| Amyloid-beta PET Imaging With 18F-92 in Alzheimer's Disease 18F-92 - Alzheimer's Disease | Phase 2 | Unknown | First Affiliated Hospital of Fujian Medical University | 50 | 2021-07-01 | 2021-12-06 |
| RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY RT001, Placebo - Progressive Supranuclear Palsy | Phase 2 | Unknown | Biojiva LLC | 40 | 2021-06-23 | 2021-06-25 |
| Rho Kinase (ROCK) Inhibitor in Tauopathies - 1 Fasudil - Progressive Supranuclear Palsy, Corticobasal Syndrome | Phase 2 | Unknown | Woolsey Pharmaceuticals | 15 | 2021-01-22 | 2022-06-03 |
| Evaluation of Tolfenamic Acid in Individuals With PSP at 12-Weeks Tolfenamic Acid, Placebos - Progressive Supranuclear Palsy | Phase 1 / Phase 2 | Unknown | NeuroTau, Inc. | 24 | 2021-01-01 | 2020-02-05 |
Showing 20 of 67. Sign in to see all of them.
Alzheimer Disease (61) · Cognitive Dysfunction (11) · Dementia (7) · Supranuclear Palsy, Progressive (6) · Dementia, Vascular (3) · Atherosclerosis (2) · Frontotemporal Dementia (2) · Memory Disorders (2) · Plaque, Amyloid (2) · Alzheimer disease type 1 (1) · Alzheimer disease type 2 (1) · Alzheimer disease, familial, type 3 (1) · Amyloidosis (1) · Autoimmune Diseases (1) · Brain Diseases (1)
Brain Diseases (66) · Central Nervous System Diseases (66) · Nervous System Diseases (66) · Neurodegenerative Diseases (66) · Mental Disorders (62) · Neurocognitive Disorders (62) · Dementia (55) · Pathological Conditions, Signs and Symptoms (11) · Cognition Disorders (10) · Neurologic Manifestations (9) · Signs and Symptoms (9) · Basal Ganglia Diseases (8) · Movement Disorders (8) · Cardiovascular Diseases (6)
Donepezil (6) · Sodium Chloride (2) · florbetapir (2) · 2-Hydroxypropyl-beta-cyclodextrin (1) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Acupuncture Therapy (1) · Bryostatins (1) · Dronabinol (1) · Electroacupuncture (1) · Fish Oils (1) · Injections (1) · Interferon alpha-2 (1) · Interleukin-2 (1) · Levetiracetam (1) · Liraglutide (1)
Chang Gung Memorial Hospital (7) · Fujian Medical University Union Hospital (2) · Oregon Health and Science University (2) · The Methodist Hospital Research Institute (2) · Zhejiang Hisun Pharmaceutical Co. Ltd. (2) · APRINOIA Therapeutics, LLC (1) · Adeona Pharmaceuticals (1) · Affiliated Hospital to Academy of Military Medical Sciences (1) · American Society Of Thermalism And Climatology Inc (1) · Aphios (1) · Banner Health (1) · Biojiva LLC (1) · Blanchette Rockefeller Neurosciences Insitute (1) · CHABiotech CO., Ltd (1) · Centre Hospitalier Universitaire de Nice (1)
United States (22) · China (12) · Taiwan (6) · Brazil (3) · Australia (2) · France (2) · Germany (2) · Israel (2) · Italy (2) · Netherlands (2) · South Korea (2) · Japan (1) · Singapore (1) · United Kingdom (1)
Alexander Kaplan (1) · Alissa Ash, Dr. (1) · Bertrand Gaymard, MD, PhD (1) · Bin Zhang, M.D. Ph.D. (1) · Breno S Diniz, MD, PhD (1) · Carolyn Liebsack, BSN (1) · Chao-Yi Wu, PhD (1) · Coad T Dow, MD (1) · Cornelia Reininger, M.D., PhD (1) · Daniel E. Grosz, MD (1) · Daniela Berg, Doctor (1) · David Newsome, M.D. (1) · David Russell, M.D., Ph.D (1) · Dongsheng Fan, M.D. (1) · Evaristus Nwulia, MD (1)
PMID 21525519, PMID 24438512, PMID 25093483, PMID 27160012, PMID 27871675, PMID 28673322, PMID 30450044, PMID 30934894, PMID 30944040, PMID 30947755, PMID 33883015, PMID 33933117, PMID 34712113, PMID 34856171, PMID 36170815, PMID 37859748, PMID 37859768, PMID 39088212, PMID 39176240, PMID 40049590, PMID 40235521, PMID 40615880, PMID 41326666, PMID 42032764
P30AG024978 (1), R01AG025502 (1), R01AG043398 (1), R44AG061981 (1), R44AG071388 (1)