10 completed, 3 recruiting, 2 enrolling by invitation, 2 unknown. 11 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Recruiting 3, Enrolling by invitation 2, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Systemic Inflammatory Response: new trials by email Literature Review of Systemic Inflammatory Response trials Research Report on Systemic Inflammatory Response
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ulinastatin on Systemic Immune-Inflammation in Patients With Complicated Intra-Abdominal Infection ulinastatin, Normal Saline (0.9% NaCl) - Complicated Intra-abdominal Infection (cIAI), Systemic Inflammatory Response | Not applicable | Not yet recruiting | Fujian Medical University Union Hospital | 165 | 2026-10-30 | 2026-06-29 |
| The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm. Overnight Active Temperature Regulation: Eight Sleep Pod System - Poor Sleep Quality, Gut Microbiome | Not applicable | Recruiting | Eight Sleep Inc. | 100 | 2026-10-01 | 2026-10-26 |
| Improving Health Outcomes With Kefir Traditional Kefir, Milk (placebo) - Systemic Inflammatory Response, Diabetes Mellitus, Type 2 | Not applicable | Recruiting | University of Alberta | 156 | 2026-03-24 | 2026-05-08 |
| The Effect of Pectin Supplementation on Geriatric With Frailty: A Randomised Placebo-Controlled Dietary Intervention Study Pectin, Whey protein - Frailty at Older Adults, Pre-Frailty | Not applicable | Recruiting | University of Nottingham | 30 | 2025-02-10 | 2025-06-22 |
| HomeStyles-Adults of Chinese Heritage HomeStyles-China - Healthy Lifestyle, Home Environment Related Disease | Not applicable | Enrolling by invitation | Rutgers, The State University of New Jersey | 400 | 2024-08-25 | 2026-05-07 |
| PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) Erythropoietin, blood transfusion - Anemia, Coronary Disease | Phase 2 | Unknown | Federal University of São Paulo | 120 | 2024-06-01 | 2024-08-07 |
| SHADES Mechanistic Trial Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I - Insomnia, Insomnia Chronic | Not applicable | Enrolling by invitation | Indiana University | 200 | 2024-04-25 | 2026-08-06 |
| Evaluation of the Consumption of Lupins in Brine on Metabolic Markers in Healthy Individuals 4-week lupins in brine consumption, 4-week lupins in brine consumption and dietary suggestion - Lipid Disorder, Systemic Inflammatory Response | Not applicable | Completed | University of Teramo | 60 | 2024-04-18 | 2024-09-19 |
| Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement Placebo, Dexmedetomidine 0.5mcg/kg/h, Dexmedetomidine 1 mcg/kg/h - Systemic Inflammatory Response, Aortic Valve Stenosis | Phase 3 | Completed | University Hospital Dubrava | 60 | 2022-11-22 | 2025-03-30 |
| Effect Dietary Fibre Supplementation on Gut Microbiota Composition Pectin dosages - Diet, Healthy, Systemic Inflammatory Response | Not applicable | Completed | Elizabeth Simpson | 15 | 2022-10-05 | 2025-01-06 |
| To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study) cryoablation - Cancer, Treatment-Related, Tumor of Breast | Not applicable | Completed | University of Roma La Sapienza | 20 | 2022-09-01 | 2023-02-14 |
| CCTA Coronary Hemodynamics, Systemic Inflammation and Vulnerable Plaques (COHESIVE) Cardiac imaging tests, Venous blood sample collection - Coronary Artery Disease, Systemic Inflammatory Response | Unknown | Cardio Med Medical Center | 100 | 2022-08-05 | 2023-05-16 | |
| Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation Fibre intervention, Placebo intervention - Diet, Healthy, Systemic Inflammatory Response | Not applicable | Completed | Elizabeth Simpson | 30 | 2021-09-22 | 2025-03-28 |
| The Effects of Dietary Fibres on Metabolic Health and the Gut Microbiome Pectin, Maltodextrin - Diet, Healthy | Not applicable | Completed | Elizabeth Simpson | 19 | 2021-09-09 | 2024-08-30 |
| Inflammation Indıces and Mortality in Adult Crush Syndrome Crush Syndrome, Rhabdomyolysis | Completed | Ataturk University | 325 | 2018-01-01 | 2026-08-18 | |
| The Effect of Influenza Vaccination on the Systemic Inflammatory Response and Myocardial Protection in Patients Undergoing Cardiac Surgery: a Randomized Controlled Trial Influenza Vaccine, Placebo - Systemic Inflammatory Response | Phase 4 | Completed | Health Sciences North Research Institute | 30 | 2015-09-01 | 2026-10-05 |
| PK/PD of EA-230 During Endotoxemia EA-230, Endotoxin, Placebo - Endotoxemia, Systemic Inflammatory Response | Phase 1 | Completed | Radboud University Medical Center | 60 | 2015-02-01 | 2016-06-23 |
| Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers Lung Function, Heart Rate Variability | Completed | InCor Heart Institute | 222 | 2008-12-01 | 2011-06-10 |
Inflammation (4) · Coronary Artery Disease (3) · Cardiovascular Diseases (2) · Sleep Initiation and Maintenance Disorders (2) · Anemia (1) · Aortic Valve Stenosis (1) · Atherosclerosis (1) · Breast Neoplasms (1) · Chronic Disease (1) · Coronary Disease (1) · Coronary Occlusion (1) · Coronary Stenosis (1) · Critical Illness (1) · Crush Syndrome (1) · Diabetes Mellitus (1)
Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (8) · Cardiovascular Diseases (4) · Nutritional and Metabolic Diseases (4) · Vascular Diseases (4) · Arterial Occlusive Diseases (3) · Arteriosclerosis (3) · Heart Diseases (3) · Metabolic Diseases (3) · Myocardial Ischemia (3) · Coronary Disease (2) · Disease Attributes (2) · Dyssomnias (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2)
Pectins (2) · Sodium Chloride (2) · Blood Transfusion (1) · Cryosurgery (1) · Dexmedetomidine (1) · Endotoxins (1) · Erythropoietin (1) · Hygiene (1) · Influenza Vaccines (1) · Lipopolysaccharides (1) · Milk (1) · Saline Solution (1) · Whey Proteins (1) · alanyl-glutaminyl-glycyl-valine (1) · maltodextrin (1)
Elizabeth Simpson (3) · Ataturk University (1) · Cardio Med Medical Center (1) · Eight Sleep Inc. (1) · Federal University of São Paulo (1) · Fujian Medical University Union Hospital (1) · Health Sciences North Research Institute (1) · InCor Heart Institute (1) · Indiana University (1) · Radboud University Medical Center (1) · Rutgers, The State University of New Jersey (1) · University Hospital Dubrava (1) · University of Alberta (1) · University of Nottingham (1) · University of Roma La Sapienza (1)
United Kingdom (4) · United States (3) · Brazil (2) · Canada (2) · Italy (2) · China (1) · Croatia (1) · Netherlands (1) · Romania (1) · Turkey (Türkiye) (1)
Ana Valdes, Professor (2) · Ana Valdes, PhD (1) · Carol Byrd-Bredbenner (1) · David He, PhD (1) · Diana Opincariu, MD, PhD (1) · Donato Angelino, PhD (1) · Federica Pediconi, MD (1) · Jesse C Stewart, Ph.D. (1) · Mauro Serafini, PhD (1) · Noor K Al-Tameemi, PhD student candidate (1) · P Pickkers, MD, Prof. (1) · Professor Ana Valdes, PhD student candidate (1) · Roni E Atoui, MSc MD FRCSC (1) · Zrinka Safaric Oremus, MD (1)
PMID 15770533, PMID 25229334, PMID 27566765, PMID 28050693, PMID 30919998, PMID 39436590, PMID 42803883
P50MD017356 (1), R01HL165115 (1)