34 completed, 14 unknown, 6 active not recruiting, 6 recruiting. 28 Not applicable, 5 Phase 3, 5 Phase 4, 2 Phase 2, 1 Early Phase 1.
Follow Coronary Occlusion: new trials by email Literature Review of Coronary Occlusion trials Research Report on Coronary Occlusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drug-Coated Balloon Only Strategy After Recanalization of Chronic Total Coronary Occlusions Paclitaxel-coated balloon (AGENT Paclitaxel-Coated PTCA Balloon Catheter), Serial intravascular ultrasound and protocol-mandated nine-month angiographic reassessment - Angina (Stable), Coronary Occlusion | Not applicable | Not yet recruiting | University of Sao Paulo General Hospital | 38 | 2026-11-01 | 2026-09-14 |
| Machine Learning for Diagnosis of Occlusive MI in LBBB Patients Digital 12-Lead ECG Analysis and Invasive Coronary Angiography - Acute Myocardial Infarction (AMI), Left Bundle Branch Block | Recruiting | Konya City Hospital | 50 | 2026-06-01 | 2026-06-02 | |
| PCI Registry Basel Coronary Artery Disease, Coronary Stenosis | Recruiting | University Hospital, Basel, Switzerland | 10000 | 2025-10-01 | 2026-09-10 | |
| Antegrade Dissection and Re-entry Versus Retrograde Strategy in CTO PCI CTO PCI using ADR strategy, CTO PCI using retrograde strategy - Coronary Artery Disease, Coronary Occlusion | Not applicable | Recruiting | National Institute of Cardiology, Warsaw, Poland | 74 | 2025-07-28 | 2026-01-02 |
| Polish Registry of Percutaneous Coronary Intervention for Chronic Total Occlusions Coronary Occlusion, Percutaneous Coronary Intervention | Recruiting | National Institute of Cardiology, Warsaw, Poland | 1000 | 2025-05-21 | 2026-01-09 | |
| A MAajor RAdiation-based PCI Study in STEMI and NSTEMI Non Complex PCI, Complex PCI - Myocardial Infarction (MI), Radiation Toxicity | Active not recruiting | Centre Cardiologique du Nord | 15630 | 2025-03-01 | 2026-08-21 | |
| AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS Acute Coronary Syndrome, STEMI | Active not recruiting | Powerful Medical | 800 | 2024-12-10 | 2026-03-20 | |
| Comparative of Plasma Proteomics & Metabolomics in Coronary Artery Disease: Obstructive,Non-Obstructive, & No Lesions Coronary Arterial Disease (CAD) | Recruiting | University of Sao Paulo General Hospital | 66 | 2024-08-01 | 2025-03-28 | |
| PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) Erythropoietin, blood transfusion - Anemia, Coronary Disease | Phase 2 | Unknown | Federal University of São Paulo | 120 | 2024-06-01 | 2024-08-07 |
| Single-Arm Study Evaluating Use of the CORA Catheters for the Crossing of Coronary Chronic Total Occlusions coraFlex Catheter, coraForce Catheter, coraCross Catheter - Coronary Occlusion | Phase 3 | Unknown | ReFlow Medical, Inc. | 150 | 2024-06-01 | 2024-05-10 |
| Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease SeQuent® Please NEO drug-coated balloon catheter, Current-generation drug-eluting stent - Coronary Artery Disease, Myocardial Ischemia | Not applicable | Active not recruiting | B. Braun Medical Industries Sdn. Bhd. | 1436 | 2023-09-07 | 2026-05-28 |
| Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients Ultimaster Nagomi™ - Cardiovascular Disease, Coronary Artery Occlusion | Active not recruiting | Terumo Europe N.V. | 3000 | 2023-04-25 | 2026-07-10 | |
| Impact of a Corrie Cardiac Rehabilitation Program Corrie Hybrid Cardiac Rehabilitation Program - Coronary Artery Disease, Myocardial Infarction | Not applicable | Completed | Johns Hopkins University | 259 | 2023-04-03 | 2025-12-05 |
| IVUS Analysis for Coronary Obstruction in TAVI IVUS assessment of coronary ostia - Coronary Artery Occlusion | Not applicable | Unknown | Universita di Verona | 100 | 2022-01-20 | 2022-11-09 |
| STAR and Deferred Stenting Study Stent Placement Timing - Early, Stent Placement Timing - Late - Coronary Occlusion, Coronary Stenosis | Not applicable | Completed | Saint Luke's Health System | 150 | 2021-11-23 | 2025-10-24 |
| Comparison of the Diagnostic Performance and Costs of FFRB Vs. Standard Care in Suspected Coronary Artery Disease. CTCA - Coronary Artery Disease, Cardiovascular Diseases | Active not recruiting | National Heart Centre Singapore | 340 | 2021-10-01 | 2024-11-08 | |
| ANGiographic Evaluation of Left Main Coronary Artery INtErvention Angiography and Clinical Follow up, Clinical Follow up - Coronary Occlusion, Left Main Coronary Artery Disease | Not applicable | Active not recruiting | Fundación EPIC | 400 | 2021-04-16 | 2026-10-08 |
| A Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease The CAD-det Validation Study CAD-det - Coronary Artery Disease, Cardiovascular Diseases | Not applicable | Unknown | AusculSciences Canada Inc. | 395 | 2021-03-01 | 2020-09-24 |
| Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor, coronary wires. or coronary balloons, drug-coated balloon - Coronary Artery Disease, Coronary Occlusion | Not applicable | Unknown | Beijing Anzhen Hospital | 200 | 2021-02-01 | 2021-02-09 |
| Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First) CTO PCI with the first-choice Gladius guidewire, CTO PCI without the first-choice Gladius guidewire - Coronary Artery Disease, Coronary Occlusion | Not applicable | Completed | National Institute of Cardiology, Warsaw, Poland | 69 | 2021-01-01 | 2024-10-08 |
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Coronary Artery Disease (31) · Coronary Stenosis (15) · Myocardial Ischemia (12) · Coronary Disease (10) · Acute Coronary Syndrome (8) · Cardiovascular Diseases (7) · Myocardial Infarction (7) · Angina Pectoris (5) · Atherosclerosis (5) · Coronary Restenosis (3) · Coronary Thrombosis (3) · Heart Diseases (3) · Ischemia (3) · Non-ST Elevated Myocardial Infarction (3)
Vascular Diseases (64) · Heart Diseases (63) · Cardiovascular Diseases (59) · Coronary Disease (56) · Myocardial Ischemia (54) · Arterial Occlusive Diseases (31) · Arteriosclerosis (31) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (14) · Neurologic Manifestations (11) · Pain (11) · Signs and Symptoms (11) · Chest Pain (9) · Necrosis (8) · Infarction (7)
Percutaneous Coronary Intervention (7) · Acetylcysteine (1) · Aspirin (1) · Atorvastatin (1) · Blood Transfusion (1) · Breathing Exercises (1) · Clopidogrel (1) · Clostridium perfringens epsilon-toxin (1) · Coronary Artery Bypass (1) · Decision Support Techniques (1) · Drug-Eluting Stents (1) · Erythropoietin (1) · HBOC 201 (1) · Ischemic Postconditioning (1) · Mass Screening (1)
Abbott Medical Devices (5) · National Institute of Cardiology, Warsaw, Poland (4) · AusculSciences Canada Inc. (2) · Insel Gruppe AG, University Hospital Bern (2) · Nitiloop Ltd. (2) · Seung-Jung Park (2) · University of Sao Paulo General Hospital (2) · Anesiva, Inc. (1) · Angel Medical Systems (1) · Angioslide Ltd. (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · B. Braun Medical Industries Sdn. Bhd. (1) · Beijing Anzhen Hospital (1) · Biopure Corporation (1)
United States (13) · Poland (6) · Switzerland (6) · France (5) · Canada (4) · Italy (4) · Japan (4) · South Korea (4) · Spain (4) · United Kingdom (4) · Belgium (3) · Brazil (3) · Austria (2) · China (2) · Germany (2)
Ken Kozuma, MD (2) · Simon Walsh, MD (2) · A. Gerson Greenburg, MD, PhD (1) · Abhiram Prasad, MBBS (1) · Angela Hoye, MB, ChB, PhD (1) · Antonio D Freire, MD, PhD (1) · Ashok Seth, MD (1) · Ben Chow, MD (1) · Benjamin Chow, MD, FRCP(C) (1) · Bradley H Strauss, MD, PhD (1) · Christian Seiler (1) · Dale Adler, MD (1)
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