10 recruiting, 8 completed, 2 terminated, 2 unknown. 7 Not applicable, 2 Phase 3, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Recruiting 5, Completed 1, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Sudden Unexpected Death in Epilepsy: new trials by email Literature Review of Sudden Unexpected Death in Epilepsy trials Research Report on Sudden Unexpected Death in Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intracranial CArtography of Cortical Contribution to Respiratory Load Compensation in Epilepsy SEEG monitoring, Comprehensive respiratory monitoring, Cardio-respiratory monitoring - Epilepsy, SUDEP | Not applicable | Recruiting | Hospices Civils de Lyon | 20 | 2026-09-17 | 2026-09-23 |
| Study of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant Epilepsy MRI scan, electrocardiogram - Epilepsy, Hypothalamus | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 20 | 2026-09-10 | 2026-10-22 |
| A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome [18F]MPPF PET-MRI - Epilepsy, Dravet Syndrome | Not applicable | Recruiting | Hospices Civils de Lyon | 30 | 2026-05-04 | 2026-05-08 |
| The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project Fenfluramine treatment (Fintepla), Hypercapnia Challenge using the device (RespirAct) - Dravet Syndrome | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 25 | 2026-04-27 | 2026-07-15 |
| Effect of Rose Odor Exposure on Ictal Apnea 2-phenylethanol rose scent - Epilepsy, Sudden Unexpected Death in Epilepsy | Early Phase 1 | Recruiting | Vanderbilt University Medical Center | 40 | 2025-07-01 | 2026-06-11 |
| Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLepsy Video-EEG monitoring, Respiratory monitoring and polysomnography, 1 Hypercapnic challenge while participant is awake - Epilepsy | Not applicable | Recruiting | Hospices Civils de Lyon | 60 | 2024-11-04 | 2026-03-27 |
| The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study Pneumowave - Sleep Disordered Breathing, Apnea of Prematurity | Recruiting | NHS Greater Clyde and Glasgow | 225 | 2024-03-01 | 2026-04-14 | |
| Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study Video-Electroencephalography - Sudden Unexpected Death in Epilepsy, Near-Sudden Unexpected Death in Epilepsy | Unknown | Liu Yonghong | 30 | 2022-04-01 | 2024-01-18 | |
| Carbon Dioxide (CO2) Chemosensitivity and SUDEP 6% Carbon dioxide/50% oxygen/balance nitrogen mixture - Epilepsy, SUDEP | Not applicable | Recruiting | University of Iowa | 335 | 2019-12-12 | 2026-06-23 |
| Improving Patient Communication About SUDEP CHICA SUDEP module - SUDEP, Epilepsy | Not applicable | Completed | Indiana University | 103 | 2018-06-14 | 2022-02-08 |
| Abnormal Ventilatory Response to Carbon Dioxide: a Potential Biomarker for Seizure Induced Respiratory Depression & Modification by SSRI Fluoxetine, Placebo - Epilepsy, SUDEP | Phase 2 | Completed | Rup Kamal Sainju | 30 | 2017-02-16 | 2020-05-04 |
| Phenomenological Approach of Epilepsy in Patients With Epilepsy interview with a psychologist - Epilepsy | Completed | University Hospital, Montpellier | 30 | 2016-09-01 | 2022-08-11 | |
| Neural Circulatory Control and SUDEP Risk. Epilepsy, Seizures | Active not recruiting | Mayo Clinic | 39 | 2016-06-01 | 2026-09-11 | |
| Genetic Markers of Cardiovascular Disease in Epilepsy Epilepsy, Seizures | Recruiting | Mayo Clinic | 600 | 2016-05-01 | 2025-09-08 | |
| Efficacy of Naloxone in Reducing Postictal Central Respiratory Dysfunction in Patients With Epilepsy naloxone, Placebo - Epilepsy | Phase 3 | Completed | Hospices Civils de Lyon | 485 | 2015-06-26 | 2025-09-26 |
| Cardiac Arrhythmias in Dravet Syndrome Epilepsy | Completed | Stichting Epilepsie Instellingen Nederland | 59 | 2015-06-01 | 2018-09-07 | |
| Serotoninergic Pathways in Sudden and Unexpted Death in Epilepsy (SUDEP) Brain samples, Skin samples - Sudden Unexpected Death in Epilepsy (SUDEP) | Terminated | Hospices Civils de Lyon | 2 | 2014-01-01 | 2019-04-03 | |
| Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring Unit oxygen - Epilepsy | Not applicable | Terminated | NYU Langone Health | 5 | 2013-08-01 | 2017-03-13 |
| Risk Factors of SUDEP Interview with a psychologist and self-reported questionnaires - Epilepsy | Unknown | University Hospital, Montpellier | 408 | 2011-07-01 | 2017-03-08 | |
| Risk Factors for Sudden Unexplained Death in Epilepsy SUDEP | Recruiting | NYU Langone Health | 800 | 2011-06-01 | 2026-06-04 |
Showing 20 of 23. Sign in to see all of them.
Epilepsy (22) · Seizures (4) · Epilepsies, Myoclonic (3) · Death, Sudden, Cardiac (2) · Apnea (1) · Arrhythmias, Cardiac (1) · Cardiomyopathies (1) · Channelopathies (1) · Drug Resistant Epilepsy (1) · Long QT Syndrome (1) · Polymorphic Catecholaminergic Ventricular Tachycardia (1) · Sleep Apnea Syndromes (1) · Syncope (1)
Brain Diseases (23) · Central Nervous System Diseases (23) · Death (23) · Death, Sudden (23) · Nervous System Diseases (23) · Pathologic Processes (23) · Pathological Conditions, Signs and Symptoms (23) · Signs and Symptoms (5) · Neurologic Manifestations (4) · Cardiovascular Diseases (3) · Epilepsy, Generalized (3) · Epileptic Syndromes (3) · Heart Diseases (3) · Heart Arrest (2) · Arrhythmias, Cardiac (1)
Fluoxetine (2) · Interviews as Topic (2) · Surveys and Questionnaires (2) · Fenfluramine (1) · Magnetic Resonance Spectroscopy (1) · Naloxone (1) · Oxygen (1)
Hospices Civils de Lyon (7) · Mayo Clinic (2) · NYU Langone Health (2) · University Hospital, Montpellier (2) · Centre Hospitalier Universitaire, Amiens (1) · Indiana University (1) · Liu Yonghong (1) · MedtronicNeuro (1) · NHS Greater Clyde and Glasgow (1) · Rup Kamal Sainju (1) · Stichting Epilepsie Instellingen Nederland (1) · The University of Texas Health Science Center, Houston (1) · University of Iowa (1) · Vanderbilt University Medical Center (1)
France (10) · United States (9) · United Kingdom (2) · China (1) · Germany (1) · Netherlands (1)
Brian Gehlbach, MD (1) · George Richerson, MD, PhD (1) · Marie-Christine Picot, MD, PhD (1) · Orrin Devinsky, MD (1) · Randall W Grout, MD (1) · Roland Thijs, Dr. (1) · Ross J Langley, MBChB BSc PhD MRCPCH (1) · Rup Sainju (1) · Samden Lhatoo, MD, FRCP (1) · Virend K Somers, MD PhD (1) · Virend K. Somers, MD PhD (1)
PMID 12892358, PMID 21896964, PMID 23733842, PMID 27384980, PMID 27809868, PMID 30795595, PMID 31304358, PMID 33598905, PMID 40887117
2014 (1), R01NS113764 (1)