4 completed, 3 unknown, 2 enrolling by invitation, 2 recruiting. 1 Early Phase 1, 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 1 | Recruiting 1 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Enrolling by invitation 1 |
| Phase 2 | 1 | Completed 1 |
Follow Channelopathies: new trials by email Literature Review of Channelopathies trials Research Report on Channelopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Physical Activity and Functional Capacity in Patients With Congenital Long QT Syndrome Questionnaires, Cardiopulmonary exercise testing, 24-hour Holter monitoring - Long QT Syndrome, Channelopathies | Not yet recruiting | University of Sao Paulo | 120 | 2026-11-01 | 2026-10-07 | |
| Aprepitant for the Treatment of CLIFAHDD Aprepitant Powder for Oral Suspension - CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay | Early Phase 1 | Recruiting | The University of Texas Health Science Center at San Antonio | 5 | 2026-10-31 | 2026-10-05 |
| A Phase 1b Study of BHV-7000 in Participants With Inherited Erythromelalgia BHV-7000, Placebo - Familial Erythromelalgia | Phase 1 | Enrolling by invitation | Biohaven Therapeutics Ltd. | 5 | 2026-01-15 | 2026-04-08 |
| Mutation-specific Therapy for the Long QT Syndrome Lumacaftor / Ivacaftor, Orkambi® Oral Tablet - Long QT Syndrome | Phase 2 | Completed | Istituto Auxologico Italiano | 16 | 2021-06-15 | 2025-04-25 |
| Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial Ajmaline - Brugada Syndrome, Channelopathies | Unknown | Universitair Ziekenhuis Brussel | 25 | 2020-11-16 | 2021-12-08 | |
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives Genetic analysis - Channelopathies | Unknown | D'Or Institute for Research and Education | 100 | 2018-01-01 | 2021-04-06 | |
| Genetic Markers of Cardiovascular Disease in Epilepsy Epilepsy, Seizures | Recruiting | Mayo Clinic | 600 | 2016-05-01 | 2025-09-08 | |
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies Dental restorative procedure - Channelopathies, Brugada Syndrome | Not applicable | Completed | University of Sao Paulo General Hospital | 31 | 2015-05-01 | 2024-04-09 |
| Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS) | Enrolling by invitation | Johns Hopkins University | 100 | 2013-08-01 | 2026-01-16 | |
| Sudden Cardiac Death - Screening Of Risk Factors ECG and survey screening - Sudden Cardiac Death, Cardiomyopathies | Unknown | University of Coimbra | 15351 | 2012-02-01 | 2017-06-12 | |
| Characteristics of Andersen-Tawil Syndrome Andersen-Tawil Syndrome, Andersen Syndrome | Completed | University of Rochester | 28 | 2007-11-01 | 2013-01-16 | |
| Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement Disorders Hyperkinesis | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 40 | 2003-01-01 | 2008-03-04 |
Long QT Syndrome (5) · Arrhythmias, Cardiac (4) · Death, Sudden, Cardiac (4) · Brugada Syndrome (3) · Cardiomyopathies (2) · Polymorphic Catecholaminergic Ventricular Tachycardia (2) · Andersen Syndrome (1) · Arrhythmogenic Right Ventricular Dysplasia (1) · Ataxia (1) · Cardiomyopathy, Dilated (1) · Cardiomyopathy, Hypertrophic (1) · Chorea (1) · Death (1) · Death, Sudden (1)
Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Cardiovascular Diseases (10) · Heart Diseases (8) · Cardiac Conduction System Disease (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Cardiovascular Abnormalities (6) · Congenital Abnormalities (6) · Heart Defects, Congenital (6) · Nervous System Diseases (6) · Arrhythmias, Cardiac (5) · Death (5) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Death, Sudden (4)
Ajmaline (1) · Aprepitant (1) · Electrocardiography, Ambulatory (1) · Exercise Test (1) · Genetic Testing (1) · Surveys and Questionnaires (1) · Suspensions (1) · epicatechin gallate (1) · ivacaftor (1) · lumacaftor (1) · lumacaftor, ivacaftor drug combination (1)
Biohaven Therapeutics Ltd. (1) · D'Or Institute for Research and Education (1) · Istituto Auxologico Italiano (1) · Johns Hopkins University (1) · Mayo Clinic (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · The University of Texas Health Science Center at San Antonio (1) · Universitair Ziekenhuis Brussel (1) · University of Coimbra (1) · University of Rochester (1) · University of Sao Paulo (1) · University of Sao Paulo General Hospital (1)
United States (6) · Brazil (3) · Italy (2) · Belgium (1) · Canada (1) · Portugal (1) · United Kingdom (1)
Ana CG Oliveira, S (1) · Andreas Barth, MD (1) · Cesar J Gruppi, PhD (1) · Denise Hachul, PhD (1) · Emma Ciafaloni, MD (1) · Francisco CC Darrieux, PhD (1) · Itamara LI Neves, PhD (1) · Lia Crotti, MD (1) · Luciana Sacilotto, S (1) · Megan Iammarino, DPT (1) · Nilson O Araujo, Dr (1) · Peter J Schwartz, MD (1) · Ricardo S Neves, PhD (1) · Robert C. Griggs, MD (1)
PMID 11136691, PMID 15454078, PMID 15898165, PMID 16009809, PMID 19017345, PMID 19926015, PMID 20513597, PMID 21403098, PMID 21459272, PMID 21810866, PMID 22000298, PMID 22715240, PMID 22995932, PMID 23128497, PMID 23266818, PMID 23994779, PMID 24076289, PMID 25741868, PMID 27916777, PMID 27993330, PMID 28146053, PMID 31319747, PMID 7889574
R01HL128743 (1), U54RR019482 (1)