11 completed, 4 unknown, 3 recruiting, 1 not yet recruiting. 21 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 21 | Completed 11, Unknown 4, Recruiting 3, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Stomatitis: new trials by email Literature Review of Stomatitis trials Research Report on Stomatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer. Dexamethasone mouthwash, Datopotamab Deruxtecan (Dato-DXd) - Stomatitis | Phase 4 | Recruiting | AstraZeneca | 100 | 2026-06-24 | 2026-10-28 |
| Using a Steroid Mouthwash to Prevent Mouth Sores During Chemotherapy Dexamethasone Mouthwash - Oral Mucositis Due to Chemotherapy | Phase 4 | Recruiting | Woman's | 45 | 2026-04-02 | 2026-06-25 |
| HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat - Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis | Phase 4 | Not yet recruiting | Haiphong University of Medicine and Pharmacy | 228 | 2026-01-20 | 2026-01-27 |
| Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis zinc oxide, Placabo - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Faculty of Dental Medicine for Girls | 100 | 2025-06-30 | 2026-05-04 |
| Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients PBM Therapy, Maalox plus Benadryl - Aphthous Ulcer | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 30 | 2025-03-10 | 2025-03-25 |
| The Efficacy of Erythropoietin Oral Gel Versus Erythropoietin Mouthwash in the Management of Recurrent Aphthous Stomatitis Epoetin 4000, Placebo - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Future University in Egypt | 60 | 2024-07-01 | 2025-08-26 |
| Is Hyaluronic Acid Gel Effective on Oral Mucositis in Children Who Receiving Chemotherapy Hyaluronic acid, Sodium bicarbonate - Oral Mucositis | Phase 4 | Completed | Yuzuncu Yil University | 40 | 2022-04-01 | 2023-04-18 |
| OZOCLO_MUCOSITIS: a New Protocol for Prevention of Oral Mucositis 1. alpha acid lipoic - tables, 2. ozonated oil - mouthwash, 3. chlorhexidine 0,2% - mouthwash - Mucositis (MeSH Unique ID: D052016), Stomatitis (MeSH Unique ID: D013280) | Phase 4 | Unknown | University of Palermo | 80 | 2022-03-10 | 2022-01-27 |
| Benzydamine Oromucosal Solution in Oral Mucositis (BOOM) Benzydamine Hydrochloride 0.15% w/v oromucosal solution - Radiation-Induced Mucositis, Head and Neck Cancer | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 100 | 2021-12-06 | 2022-11-16 |
| Effects of Oral Care With Glutamine on Oral Health, Oral Flora and Incidence of Pneumonia After Neurosurgery With Microbiome Analysis Glutamine, Normal saline - Oral Mucositis, Pneumonia | Phase 4 | Unknown | Yanzhao | 100 | 2019-01-01 | 2023-04-27 |
| Apremilast for RAS Apremilast 30mg - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Mayo Clinic | 15 | 2018-10-12 | 2022-07-14 |
| Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients Gelclair, First® Mouthwash BLM - Oral Mucositis | Phase 4 | Terminated | Midatech Pharma US Inc. | 28 | 2018-05-15 | 2019-11-22 |
| G-CSF in the Treatment of Toxic Epidermal Necrolysis recombinant granulocyte - colony stimulating factor, NaCl 0.9% - Stevens - Johnson Syndrome | Phase 4 | Completed | University of Liege | 10 | 2016-07-01 | 2025-12-31 |
| Oral Hygiene Regimen in Patients on HCT .02% Chlorohexidine Gluconate, 3% Sodium Bicarbonate, Nystatin 10000U/ml - Oral Mucositis | Phase 4 | Unknown | Riyadh Colleges of Dentistry and Pharmacy | 45 | 2015-09-01 | 2016-01-25 |
| Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer Low intensity laser for oral mucositis, Low intensity laser for oral mucositis switch off - Oral Mucositis | Phase 4 | Unknown | Fundación Pública Andaluza Progreso y Salud | 126 | 2013-01-01 | 2016-02-05 |
| Effectiveness of Hygiene Solutions on Denture Biofilm S1, S2, S3 - Stomatitis | Phase 4 | Completed | University of Sao Paulo | 64 | 2012-08-01 | 2015-04-03 |
| A Study to Evaluate the Efficacy of MuGard for the Amelioration of Oral Mucositis in Head and Neck Cancer Patients MuGard, Control Rinse - Oral Mucositis | Phase 4 | Completed | Access Pharmaceuticals, Inc. | 120 | 2011-01-01 | 2013-09-12 |
| Hexetidine and Chlorobutanol for Lesions Due to Prostheses chlorobutanol, hexetidine, Chlorhexidine - Oral Mucositis | Phase 4 | Completed | Federico II University | 44 | 2010-02-01 | 2010-05-03 |
| Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye 0.05%cyclosporin eye drop - Stevens-Johnson Syndrome | Phase 4 | Completed | Mahidol University | 31 | 2007-02-01 | 2011-12-08 |
| PROMPT - Palifermin in Reduction of Oral Mucositis in PBSC Transplantation Kepivance (Palifermin) - Non-Hodgkin's Lymphoma, Multiple Myeloma | Phase 4 | Completed | Swedish Orphan Biovitrum | 145 | 2006-04-01 | 2014-11-03 |
Showing 20 of 21. Sign in to see all of them.
Stomatitis, Aphthous (4) · Mucositis (3) · Stevens-Johnson Syndrome (3) · Head and Neck Neoplasms (2) · Arthritis, Gouty (1) · Dry Eye Syndromes (1) · Gout (1) · Hyperuricemia (1) · Lymphoma, Non-Hodgkin (1) · Multiple Myeloma (1) · Neoplasms, Squamous Cell (1) · Pneumonia (1)
Mouth Diseases (21) · Stomatognathic Diseases (21) · Immune System Diseases (4) · Chemically-Induced Disorders (3) · Dermatitis (3) · Digestive System Diseases (3) · Drug Eruptions (3) · Drug Hypersensitivity (3) · Drug-Related Side Effects and Adverse Reactions (3) · Erythema (3) · Erythema Multiforme (3) · Gastroenteritis (3) · Gastrointestinal Diseases (3) · Hypersensitivity (3)
Sodium Bicarbonate (3) · Saline Solution (2) · Allopurinol (1) · Amifostine (1) · Benzydamine (1) · Castor Oil (1) · Chlorhexidine (1) · Chlorobutanol (1) · Cyclosporine (1) · Diphenhydramine (1) · Epinephrine (1) · Febuxostat (1) · Fibroblast Growth Factor 7 (1) · Filgrastim (1) · Glutamine (1)
Access Pharmaceuticals, Inc. (1) · AstraZeneca (1) · Aziende Chimiche Riunite Angelini Francesco S.p.A (1) · Faculty of Dental Medicine for Girls (1) · Federico II University (1) · Fundación Pública Andaluza Progreso y Salud (1) · Future University in Egypt (1) · Haiphong University of Medicine and Pharmacy (1) · Mahidol University (1) · Mayo Clinic (1) · Midatech Pharma US Inc. (1) · Riyadh Colleges of Dentistry and Pharmacy (1) · Sun Pharmaceutical Industries Limited (1) · Swedish Orphan Biovitrum (1) · The University of Texas Health Science Center, Houston (1)
United States (6) · Egypt (2) · Belgium (1) · China (1) · Hungary (1) · Italy (1) · Poland (1) · Spain (1) · Thailand (1) · Turkey (Türkiye) (1)
Alison J Bruce (1) · Ashley R Edwards, PhD (1) · Brett Chiquet, DDS, PhD (1) · Daniel Torres Lagares (1) · Dimitrios Papadopoulos, MD (1) · Fernando Zarone, MD, DDS (1) · Mary Kay Delmedico, PhD (1) · Naglaa M. El-Wakeel, PhD (1) · Olga Di Fede, Professor (1) · Pinnita Prabhasawat, MD (1) · Qingsheng Zhu (1) · William Wisbeck, MD (1)
PMID 2179802, PMID 24877167, PMID 28075506, PMID 32786044, PMID 41851196