10 completed, 2 unknown, 1 not yet recruiting. 6 Not applicable, 5 Phase 2, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Unknown 2 |
| Phase 2 | 5 | Completed 4, Not yet recruiting 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CBD Knee Osteoarthritis Study Cannabidiol (CBD), Castor Oil (Placebo) - Osteoarthitis | Phase 2 | Not yet recruiting | University of Tennessee | 30 | 2026-07-01 | 2026-06-10 |
| The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles Topical Product: Almond Oil, Topical Product: Almond oil augmented with 0.5% Vitamin E, Topical Product: 0.025% Tretinoin oil augmented with castor oil - Collagen Degeneration, Wrinkle | Not applicable | Unknown | Integrative Skin Science and Research | 90 | 2024-07-22 | 2024-08-28 |
| Evaluation of Pulp Response to Castor Oil Castor oil, Formocresol - Pulp Response to Castor Oil | Not applicable | Completed | Tanta University | 31 | 2022-09-15 | 2023-02-13 |
| The Effect of Dates and Castor Oil on the Initiation of Spontaneous Labor in Primigravida Parturients Dates, Castor oil - Effect of Dates and Castor Oil on Spontaneous Labor | Not applicable | Unknown | Carmel Medical Center | 450 | 2021-08-24 | 2021-08-19 |
| Effectiveness of Castor Oil in Preventing Formal Induction of Labour in a Tertiary Institution castor oil, Water - Castor Oil, Prolonged Pregnancy | Not applicable | Completed | Assumpta Nnenna Nweke | 100 | 2021-03-05 | 2025-02-24 |
| Castror Oil for Labor Induction in Women With Previous Cesarean Section Castor Oil, placebo - Induction of Labor | Not applicable | Completed | Cairo University | 70 | 2019-07-15 | 2021-12-02 |
| Effect of Progesterone on Latent Phase Prolongation in Patients With Preterm Premature Rupture of Membranes 17-hydroxyprogesterone caproate, Castor Oil - Preterm Premature Rupture of Membrane | Phase 2 | Completed | Ain Shams University | 100 | 2018-01-10 | 2021-03-19 |
| Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease Restasis, Refresh Endura - Primary Sjogren Syndrome, Secondary Sjogren Syndrome | Phase 4 | Completed | Federal University of São Paulo | 100 | 2013-01-01 | 2020-09-22 |
| Effectiveness of Hygiene Solutions on Denture Biofilm S1, S2, S3 - Stomatitis | Phase 4 | Completed | University of Sao Paulo | 64 | 2012-08-01 | 2015-04-03 |
| Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM) 17-alpha-hydroxy-progesterone caproate, Makena®, Castor Oil (Placebo) - Preterm Delivery | Phase 2 / Phase 3 | Completed | Obstetrix Medical Group | 152 | 2011-10-01 | 2018-06-28 |
| Androgen for Leydig Cell Proliferation Testosterone undecanoate, Castor Oil - Klinefelter Syndrome, Hypergonadotropic Hypogonadism | Phase 2 / Phase 3 | Completed | University of Roma La Sapienza | 56 | 2009-06-01 | 2018-09-25 |
| Prevention of Preterm Delivery in Twin Pregnancies by 17 Alpha-hydroxyprogesterone Caproate 17-alpha Hydroxyprogesterone Caproate, Castor oil - Preterm Delivery | Phase 2 | Completed | American University of Beirut Medical Center | 290 | 2006-10-01 | 2013-07-19 |
| The Use of Castor Oil as a Labor Initiator in Post-date Pregnancies Castor oil, Sunflower oil - Prolonged Pregnancy | Not applicable | Completed | Hadassah Medical Organization | 82 | 2006-02-01 | 2012-03-20 |
Pregnancy, Prolonged (2) · Premature Birth (2) · Dry Eye Syndromes (1) · Ehlers-Danlos Syndrome (1) · Hypogonadism (1) · Infertility (1) · Klinefelter Syndrome (1) · Preterm Premature Rupture of the Membranes (1) · Stomatitis (1) · Testicular Neoplasms (1)
Ain Shams University (1) · American University of Beirut Medical Center (1) · Assumpta Nnenna Nweke (1) · Cairo University (1) · Carmel Medical Center (1) · Federal University of São Paulo (1) · Hadassah Medical Organization (1) · Integrative Skin Science and Research (1) · Obstetrix Medical Group (1) · Tanta University (1) · University of Roma La Sapienza (1) · University of Sao Paulo (1) · University of Tennessee (1)
Egypt (3) · United States (3) · Israel (2) · Brazil (1) · Italy (1) · Lebanon (1) · Nigeria (1)
Andrea Isidori, MD, PhD (1) · Andrea Lenzi, MD (1) · Andrew Combs, MD (1) · Anwar H Nassar, MD (1) · Assumpta N Nweke, MBBSMBBS (1) · Drorit Hochner-Celnikier, MD (1) · Karen C Johnson, MD, MPH (1) · Lena Sagi-Dain, MD (1) · Rossen M Hazarbassanov, PhD (1) · Shay Porat, MD (1) · Vincenzo Bonifacio, MD, PhD (1) · Yomna Bayoumi, MD (1)