3 completed, 2 unknown, 1 terminated. 6 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 3, Unknown 2, Terminated 1 |
| Phase 2 | 2 | Terminated 1, Unknown 1 |
Follow Sleep Disorder: new trials by email Literature Review of Sleep Disorder trials Research Report on Sleep Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD Pramipexole, Placebo - Sleep Disorder, Restless Legs Syndrome | Phase 2 / Phase 3 | Terminated | Massachusetts General Hospital | 75 | 2022-01-24 | 2025-09-22 |
| Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension - Autism Spectrum Disorder, Sleep Disorder | Phase 3 | Unknown | Vanda Pharmaceuticals | 100 | 2021-07-28 | 2024-03-21 |
| An Open Label Study of FT218 in Subjects With Narcolepsy FT218 - Narcolepsy, Cataplexy | Phase 3 | Completed | Avadel | 184 | 2020-06-12 | 2025-10-02 |
| The Healthy Patterns Sleep Study Attention-Control Condition, Timed Activity Intervention - Dementia, Alzheimer Disease | Phase 3 | Completed | University of Pennsylvania | 421 | 2016-05-01 | 2024-07-26 |
| Different Doses of Oral Melatonin Supplements in Chronic Kidney Disease (CKD)-Associated Sleep Disorders Melatonin - End Stage Renal Disease, Chronic Kidney Disease | Phase 2 / Phase 3 | Unknown | Southeast Renal Research Institute | 53 | 2012-12-01 | 2017-01-24 |
| A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food Trazodone, Sentra PM, Sentra PM and Trazodone (CoPack Kit Trazamine) - Sleep Disorder | Phase 3 | Completed | Targeted Medical Pharma | 111 | 2008-04-01 | 2011-11-09 |
Sleep Wake Disorders (6) · Disorders of Excessive Somnolence (2) · Parasomnias (2) · Alzheimer Disease (1) · Autism Spectrum Disorder (1) · Cataplexy (1) · Chronobiology Disorders (1) · Cognitive Dysfunction (1) · Dementia (1) · Dementia, Vascular (1) · Frontotemporal Dementia (1) · Kidney Failure, Chronic (1) · Memory Disorders (1) · Narcolepsy (1) · Nervous System Diseases (1)
Mental Disorders (6) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Nervous System Diseases (5) · Dyssomnias (3) · Sleep Disorders, Intrinsic (3) · Aberrant Motor Behavior in Dementia (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Behavior (1) · Behavioral Symptoms (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1)
Melatonin (1) · Pramipexole (1) · Trazodone (1)
Avadel (1) · Massachusetts General Hospital (1) · Southeast Renal Research Institute (1) · Targeted Medical Pharma (1) · University of Pennsylvania (1) · Vanda Pharmaceuticals (1)
United States (6) · Canada (1)
James A Tumlin, MD (1) · John W Winkelman, MD/PhD (1) · Nancy A. Hodgson (1)
PMID 33853394, PMID 34344312, PMID 39263597, PMID 42163487
R01NR015226 (1), R21DA052861 (1)