6 completed, 6 not yet recruiting, 3 recruiting, 1 active not recruiting. 10 Not applicable, 1 Early Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Not yet recruiting 5, Completed 3, Active not recruiting 1, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Does Circadian Misalignment Have Sex-Specific Effects on Metabolism? Day shift, Night shift - Circadian Misalignment, Sex Differences | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 36 | 2026-10-01 | 2026-02-27 |
| How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play? Morphine, Placebo - Stress, Early Life Stress | Not applicable | Recruiting | Sara L. Kroll | 72 | 2026-09-24 | 2026-09-28 |
| Sex-Dependent Risk of Postoperative Delirium and Mediating Effects of Family Visits Postoperative Delirium (POD), Sex Differences | Recruiting | Julian Rössler | 471 | 2026-05-05 | 2026-06-01 | |
| Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment Sleep restriction - Sleep Deprivation, Sex Differences | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 32 | 2026-04-01 | 2025-12-10 |
| The Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans GnRH antagonist, Estradiol (E2), Testosterone - Cerebral Blood Flow, Cerebral Blood Flow Regulation | Not applicable | Not yet recruiting | University of British Columbia | 50 | 2026-04-01 | 2026-02-10 |
| Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Cognitive Performance and Sex Differences Active taVNS, Sham Stimulation - Cognitive Assessment, Cognition | Not applicable | Not yet recruiting | Bahçeşehir University | 60 | 2025-12-01 | 2025-12-01 |
| Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults Immersive VR Group Dance Program, Conventional Light Physical Activity Program - Social Cognition, Healthy Aging | Not applicable | Completed | Islamic Azad University, Sanandaj | 180 | 2025-11-01 | 2026-10-06 |
| Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions - Red Blood Cell Transfusions, Sex Differences | Phase 4 | Recruiting | Michelle Zeller | 11082 | 2025-09-11 | 2026-03-12 |
| The Effect of Team Sports on the Risk of Thrombosis in Elderly Individuals in a Municipality Setting (TEAM-AGE) Team Sports, Control - Thrombosis, Exercise Training | Not applicable | Not yet recruiting | University of Copenhagen | 400 | 2024-12-30 | 2023-05-11 |
| Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum Inactivity, Physical, Aging | Not yet recruiting | University of Toronto | 80 | 2024-12-20 | 2024-12-20 | |
| Sex Differences in E-cig Perception: Study 1 E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3 - Nicotine Addiction, E-Cig Use | Not applicable | Completed | Yale University | 66 | 2024-04-30 | 2026-10-02 |
| Sex Differences in the Dilatory Response of Compound 21 Compound 21, Compound 21 + losartan - Sex Differences | Early Phase 1 | Completed | Anna Stanhewicz, PhD | 26 | 2022-10-03 | 2024-12-31 |
| Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia Video-Assisted Thoracoscopic Surgery - Sex Differences, Postoperative Sleep Quality | Unknown | Shengjing Hospital | 100 | 2021-09-20 | 2021-09-28 | |
| Sex Differences in Postoperative Sleep Quality and Inflammation Video-Assisted Thoracoscopic Surgery - Sex Differences, Postoperative Sleep Quality | Completed | Shengjing Hospital | 213 | 2020-10-31 | 2022-05-04 | |
| Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women Introduction of a lower female hs-cTn threshold - Myocardial Infarction, Sex Differences | Not applicable | Active not recruiting | BC Centre for Improved Cardiovascular Health | 24000 | 2020-02-08 | 2024-10-09 |
| Comparing the Effects of Different Types of Exercise on Glucose Handling Control Oral Glucose Tolerance Test, Mixed Exercise - Glycemic Control, Insulin Sensitivity | Not applicable | Completed | University of Waterloo | 24 | 2018-05-01 | 2024-02-06 |
| Sex Differences in Gastrointestinal Cancer Surgery Complex esophageal surgery for carcinoma, Rectum resection for carcinoma, Colon resection for carcinoma - Sex, Gastrointestinal Cancers | Completed | Medizinische Hochschule Brandenburg Theodor Fontane | 870754 | 2010-01-01 | 2025-06-12 |
Motor Activity (2) · Pain, Postoperative (2) · Acute Coronary Syndrome (1) · Cigarette Smoking (1) · Coitus (1) · Emergence Delirium (1) · Emergencies (1) · Gastrointestinal Neoplasms (1) · Insulin Resistance (1) · Multiple Endocrine Neoplasia Type 1 (1) · Myocardial Infarction (1) · Opioid-Related Disorders (1) · Sedentary Behavior (1) · Sleep Deprivation (1) · Social Behavior (1)
Behavior (6) · Pathological Conditions, Signs and Symptoms (5) · Mental Disorders (4) · Neurologic Manifestations (4) · Pathologic Processes (4) · Signs and Symptoms (4) · Postoperative Complications (3) · Cardiovascular Diseases (2) · Chemically-Induced Disorders (2) · Neoplasms (2) · Neoplasms by Site (2) · Nervous System Diseases (2) · Pain (2) · Substance-Related Disorders (2) · Vascular Diseases (2)
Thoracic Surgery, Video-Assisted (2) · Anastrozole (1) · Estradiol (1) · Gastrectomy (1) · LHRH, Ac-Nal(1)-Cpa(2)-Trp(3)-Arg(6)-Ala(10)- (1) · Losartan (1) · Morphine (1) · Proctectomy (1) · Shift Work Schedule (1) · Testosterone (1) · compound 21 (1)
Brigham and Women's Hospital (2) · Shengjing Hospital (2) · Anna Stanhewicz, PhD (1) · BC Centre for Improved Cardiovascular Health (1) · Bahçeşehir University (1) · Islamic Azad University, Sanandaj (1) · Julian Rössler (1) · Medizinische Hochschule Brandenburg Theodor Fontane (1) · Michelle Zeller (1) · Sara L. Kroll (1) · University of British Columbia (1) · University of Copenhagen (1) · University of Toronto (1) · University of Waterloo (1) · Yale University (1)
Canada (5) · United States (4) · China (3) · Switzerland (2)
Ali Veysel Ozden (1) · Anna Stanhewicz, PhD (1) · Danielle Davis (1) · Jens Bangsbo, Dr.Sci. (1) · Jingyi Qian, PhD (1) · Karin Humphries, DSc (1) · Michelle Zeller, Doctor of Medicine (1) · Philip Ainslie, PhD (1) · Sara L Kroll, Dr. (1)
2025 (1), K01DA056494 (1)