107 completed, 15 recruiting, 8 active not recruiting, 5 not yet recruiting. 97 Not applicable, 13 Phase 4, 7 Phase 3, 1 Early Phase 1, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Attention-based Binocular Training for Impaired Stereopsis (BRAVE) Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task - Amblyopia, Strabismus | Not applicable | Not yet recruiting | Centre for Eye and Vision Research | 56 | 2026-11-01 | 2026-09-03 |
| Feasibility Evaluation of WEAR-IT for Hand Therapy After Stroke Wearable Assistive and Rehabilitation robot facilitating Intensive Telerehabilitation Program, Dose-Matched Therapy Program - Stroke (6 Months or More After Onset) | Not applicable | Not yet recruiting | Dr. Rosalie Wang | 44 | 2026-09-01 | 2026-07-13 |
| Autobiographical Time Travel to Alleviate Loneliness in Older Adults Mental Time Travel Group, Social Engagement Group Activities - Aging, Loneliness | Not applicable | Not yet recruiting | Baycrest | 144 | 2026-08-15 | 2026-08-28 |
| Does Estrogen Blunt the Effects of Exercise Training on Glycemic Control EXERCISE TRAINING WITH OR WITHOUT MEDICATION - To Determine Whether Estrogen Influences the Effects of Training on Glycemic Control and Insulin Sensitivity | Not applicable | Not yet recruiting | University of Waterloo | 24 | 2026-08-01 | 2026-08-27 |
| Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment Active hf-tRNS., Placebo/sham hf-tRNS - Retinitis Pigmentosa (RP), Rod Cone Dystrophy | Not applicable | Recruiting | University of Waterloo | 20 | 2026-07-01 | 2026-07-07 |
| CHOICE+ Quality Improvement for Long Term Care Homes CHOICE+ virtual training program - Long Term Care Homes, Malnutrition Elderly | Enrolling by invitation | University of Waterloo | 800 | 2026-06-01 | 2026-08-06 | |
| Evaluation of a Novel Ocular Lubricating Eye Drop Part 2 ABR2 At least twice a day for 28 days, Part 1: ABR2 single dose in one eye - Dry Eye Syndrome (DES) | Not applicable | Recruiting | Pleryon Therapeutics (Hangzhou) Limited | 40 | 2026-05-01 | 2026-05-19 |
| Evaluation of Novel Spectacles Intended for Myopia Management in a Short-Term Study Habitual myopia glasses, Myopia Glasses A, Myopia Glasses B - Myopia: Refractive Error | Not applicable | Not yet recruiting | Myoptechs, Inc | 20 | 2026-04-15 | 2026-04-01 |
| Comparison of Ocular Lubricants in People With Symptoms of Dry Eye Propylene glycol 0.6%, 3% trehalose and 0.15% sodium hyaluronate - Dry Eye Symptoms | Phase 4 | Completed | University of Waterloo | 36 | 2026-02-23 | 2026-09-01 |
| Comparing the Fit and Performance of Scleral Lenses With Oval and Circular Limbal Zones Scleral lenses - Limbus Corneae | Phase 4 | Completed | University of Waterloo | 7 | 2026-01-13 | 2026-05-05 |
| Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach Atomoxetine, Placebo - Parkinson's Disease (PD), Freezing of Gait | Phase 3 | Recruiting | Radboud University Medical Center | 60 | 2026-01-01 | 2026-02-27 |
| Chiropractor Delivered Virtual Intervention After Vertebral frActure VIVA - Osteoporosis, Vertebral Fracture | Not applicable | Recruiting | University of Waterloo | 15 | 2025-10-20 | 2025-12-17 |
| Does the 'CATCH My Breath' Vaping Prevention Program Prevent High School Students in Ontario, Canada From Starting to Vape? CATCH My Breath - Vaping Behaviors | Not applicable | Active not recruiting | University of Ontario Institute of Technology | 5600 | 2025-10-03 | 2026-05-01 |
| Measuring Changes In Choroidal Thickness Induced By Prototype Soft Contact Lenses Worn For 1 Hour Lens A, Lens B, Lens C - Myopia; Refractive Error | Not applicable | Recruiting | Myoptechs, Inc | 20 | 2025-08-25 | 2025-09-04 |
| Quantifying Ocular Surface Aberrations After Tear Film Interventions Systane Complete Preservative-Free, Senofilcon A, Somofilcon A - Tear Film Characteristics | Phase 4 | Completed | University of Waterloo | 10 | 2025-06-10 | 2026-04-24 |
| Validation and Testing of a Novel Continuous Glucose and Continuous Ketone Monitoring Device in Healthy Volunteers Diabetes Ketoacidosis | Recruiting | University of Waterloo | 16 | 2025-03-30 | 2025-03-14 | |
| Virtual Intervention for Vertebral frActure: a Pilot, Feasibility Study for a Multicentre Randomized Controlled Trial Virtual Intervention for Vertebral Fractures (VIVA) - Osteoporosis, Fractures, Spinal | Not applicable | Completed | University of Waterloo | 34 | 2025-01-28 | 2026-04-24 |
| Freezing of Gait - Clinical Outcomes Assessment Opals, Axivity - PD - Parkinson's Disease | Recruiting | Tel-Aviv Sourasky Medical Center | 20 | 2024-10-01 | 2025-01-28 | |
| Smart Light Therapy Glasses for Sleep and Mental Wellness Lumos Glasses - Depression, Sleep Disturbance | Not applicable | Completed | University of Waterloo | 96 | 2024-09-03 | 2025-09-11 |
| Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study All nicotine/ tobacco products at market price, Nicotine vaping products at 1/2 market price, Heated tobacco products at 1/2 market price. - Cigarette Smoking, Nicotine Vaping | Not applicable | Completed | Virginia Polytechnic Institute and State University | 440 | 2024-07-29 | 2026-04-22 |
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Myopia (19) · Dry Eye Syndromes (17) · Motor Activity (11) · Osteoporosis (9) · Refractive Errors (7) · Glaucoma (6) · Chronic Disease (5) · Dementia (5) · Malnutrition (5) · Obesity (5) · Amblyopia (4) · Diabetes Mellitus (4) · Frailty (4) · Hypertension (4) · Neoplasms (4)
Exercise (6) · Contact Lenses, Hydrophilic (4) · Nutrition Assessment (2) · Nutritional Status (2) · Transcranial Direct Current Stimulation (2) · Acetazolamide (1) · Atomoxetine Hydrochloride (1) · Bupropion (1) · Cognitive Training (1) · Counseling (1) · Cyclosporins (1) · Dexetimide (1) · Diet (1) · Dosage Forms (1) · Educational Status (1)
Canada (125) · Hong Kong (7) · United States (4) · China (2) · Australia (1) · Belgium (1) · Denmark (1) · Israel (1) · Italy (1) · Netherlands (1) · Philippines (1) · Tanzania (1) · United Kingdom (1)
Lyndon Jones, PhD, FCOptom (11) · Lyndon Jones, PhD (7) · Desmond Fonn, MOptom (6) · Heather Keller, PhD (5) · Lora Giangregorio, PhD (5) · Craig Woods, PhD (4) · Marina Mourtzakis, PhD (4) · Allison Kelly, PhD (3) · Ben Thompson, PhD (3) · Benjamin Thompson, PhD (3) · Allen Cheong, PhD (2) · David Hammond, PhD (2) · Desmond Fonn, M.Optom (2) · Heather Keller (2) · James Tung, PhD (2)
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P01CA200512 (1)