410 completed, 45 unknown, 34 terminated, 32 recruiting. 236 Not applicable, 114 Phase 4, 62 Phase 2, 53 Phase 3, 41 Phase 1.
Follow Schizoaffective Disorder: new trials by email Literature Review of Schizoaffective Disorder trials Research Report on Schizoaffective Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shared Decision Making for Antipsychotic Medications The Antipsychotic Medication Decision Aid (APM-DA) - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | New York State Psychiatric Institute | 120 | 2027-01-01 | 2026-03-30 |
| Longitudinal PET Imaging of Antipsychotic Binding to the Dopamine-3 Receptor in Schizophrenia Brexpiprazole, Cariprazine, [11C] PHNO - Schizoaffective Disorder, Schizophreniform Disorder | Phase 1 | Not yet recruiting | New York State Psychiatric Institute | 100 | 2026-12-01 | 2026-07-20 |
| NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia Perceptual Discrimination Training, Cognitive Control Training - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | University of Minnesota | 168 | 2026-11-16 | 2026-11-03 |
| A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness MoodSync, Standard care - Severe Mental Illness, Bipolar Disorder | Not applicable | Not yet recruiting | Alexandria University | 60 | 2026-11-01 | 2026-10-16 |
| Integrated Psychoeducation Program for Internalized Stigma in Schizophrenia Integrated Psychoeducation Program - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | Dokuz Eylul University | 50 | 2026-10-21 | 2026-10-27 |
| Optimizing CBSST With Executive Function Training for Schizophrenia (R33) E-CBSST, E-SC - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | University of California, San Diego | 106 | 2026-10-01 | 2026-06-23 |
| Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1 Motion Perception Task, Sine Wave Speech Task, Volatility Task - SCHIZOPHRENIA 1 (Disorder), Schizoaffective Disorder | Not applicable | Recruiting | Washington University School of Medicine | 325 | 2026-10-01 | 2026-10-02 |
| Enhancing Veteran-Clinical Collaboration in VA PRRCs Collaborative Decision Skills Training, Leveling Up - Schizophrenia, Schizoaffective Disorder | Not applicable | Recruiting | VA Office of Research and Development | 119 | 2026-08-12 | 2026-08-19 |
| Cognitive Strategies in Early Psychosis 2 Modafinil, D-serine solution, Placebo - Psychosis, Schizophrenia Disorder | Phase 3 | Recruiting | University of Minnesota | 24 | 2026-07-17 | 2026-07-23 |
| MicroRNAs as Biomarkers in First Episode Schizophrenia Plasma NDE miRNA Sequencing, Whole Genome Sequencing - Schizophrenia Disorder, Schizophreniform Disorder | Not applicable | Recruiting | Northwell Health | 160 | 2026-07-01 | 2026-07-14 |
| Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys - Schizophrenia Disorder, Schizoaffective Disorder | Not applicable | Enrolling by invitation | Stanford University | 1000 | 2026-03-09 | 2026-10-23 |
| LRFN5 and OLFM4 in Schizoaffective Disorder Schizoaffective Disorder | Completed | Elazığ Mental Health and Diseases Hospital | 110 | 2026-03-02 | 2026-09-10 | |
| Improving Health Literacy in Patients With Schizophrenia Spectrum Disorder Educational sessions - Schizophrenia Disorder, Schizoaffective Disorder | Not applicable | Not yet recruiting | Louisiana State University Health Sciences Center in New Orleans | 34 | 2026-03-01 | 2026-03-23 |
| Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders Digital: Kiso Mind App - Psychosis, Psychotic Disorders | Not applicable | Recruiting | Charite University, Berlin, Germany | 60 | 2026-01-30 | 2026-03-03 |
| Impact of Medication Education on Adherence and Side Effects Medication Education Program, Routine Psychiatric Inpatient Care - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | Cumhuriyet University | 64 | 2026-01-30 | 2026-08-24 |
| State Representation in Early Psychosis 2 Early Psychosis, Psychosis | Recruiting | University of Minnesota | 500 | 2025-10-15 | 2026-09-22 | |
| Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia. 8-week outdoor physical activity program, 8-week indoor physical activity program - Schizoaffective Disorder | Not applicable | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 45 | 2025-10-07 | 2025-11-25 |
| SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities SUCCEED Community-Based Intervention - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 425 | 2025-09-18 | 2026-06-08 |
| Theta-Burst Transcranial Magnetic Stimulation for Treatment-Resistant Auditory Hallucinations Theta-Burst Transcranial Magnetic Stimulation (TBS) - Auditory Verbal Hallucinations, Schizophrenia | Not applicable | Recruiting | Ciusss de L'Est de l'Île de Montréal | 12 | 2025-09-10 | 2026-10-29 |
| Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy iTEST, Active Control - Schizophrenia Disorders, Schizoaffective Disorder | Not applicable | Recruiting | University of California, San Diego | 201 | 2025-09-01 | 2026-01-23 |
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Psychotic Disorders (548) · Schizophrenia (525) · Bipolar Disorder (105) · Mental Disorders (47) · Depressive Disorder, Major (33) · Schizophrenia, Paranoid (22) · Mood Disorders (11) · Motor Activity (11) · Substance-Related Disorders (11) · Depression (10) · Obesity (10) · Schizotypal Personality Disorder (10) · Hallucinations (9) · Metabolic Syndrome (8) · Schizophrenia Spectrum and Other Psychotic Disorders (8)
Schizophrenia Spectrum and Other Psychotic Disorders (540) · Mental Disorders (501) · Bipolar and Related Disorders (105) · Mood Disorders (104) · Behavior (69) · Pathological Conditions, Signs and Symptoms (58) · Signs and Symptoms (51) · Nervous System Diseases (36) · Depressive Disorder (31) · Neurologic Manifestations (30) · Nutritional and Metabolic Diseases (28) · Chemically-Induced Disorders (26) · Neurobehavioral Manifestations (23) · Metabolic Diseases (21) · Body Weight (20)
Risperidone (40) · Olanzapine (31) · Therapeutics (27) · Aripiprazole (23) · Paliperidone Palmitate (17) · Quetiapine Fumarate (17) · ziprasidone (16) · Cognitive Remediation (14) · Clozapine (10) · Cognitive Training (8) · Transcranial Magnetic Stimulation (8) · Cognitive Behavioral Therapy (7) · Haloperidol (7) · Transcranial Direct Current Stimulation (7) · Raloxifene Hydrochloride (6)
Centre for Addiction and Mental Health (18) · VA Office of Research and Development (18) · Dartmouth-Hitchcock Medical Center (17) · New York State Psychiatric Institute (17) · University of Maryland, Baltimore (16) · University of North Carolina, Chapel Hill (13) · US Department of Veterans Affairs (12) · University of California, San Diego (12) · Yale University (12) · University of Minnesota (11) · University of Pittsburgh (10) · Mclean Hospital (9) · Northwell Health (9) · Northwestern University (9) · Eli Lilly and Company (8)
United States (346) · Canada (36) · Germany (22) · Israel (16) · Taiwan (13) · Australia (12) · South Korea (10) · Denmark (9) · Romania (9) · Spain (9) · India (7) · Finland (6) · France (6) · Netherlands (6) · Switzerland (6)
Sophia Vinogradov, MD (6) · Dror Ben-Zeev, PhD (5) · Eric Granholm, PhD (4) · Herbert Y Meltzer, M.D. (4) · Hsin-An Chang, M.D. (4) · Jayashri Kulkarni, MBBS, MPM, FRANZCP, PhD (4) · Mark Weiser, MD (4) · Xiaoduo Fan, MD, MPH, MS (4) · A Eden Evins, MD, MPH (3) · Alan I Green, MD (3) · Alice Medalia, PhD (3)
PMID 26934062, PMID 38244179, PMID 20537128, PMID 20537130, PMID 20840778, PMID 24423017, PMID 31415936, PMID 33539561, PMID 37142273, PMID 39730881, PMID 10332540, PMID 10622350, PMID 10849191, PMID 11318766, PMID 11458304, PMID 11483142, PMID 12096176, PMID 12271808, PMID 12823166, PMID 14645311, PMID 15001724, PMID 1503131, PMID 15187072, PMID 15285956, PMID 15863743, PMID 15870612, PMID 16055815, PMID 16055817, PMID 16086610, PMID 16095473, PMID 16122909, PMID 16131943, PMID 16141449, PMID 16571581, PMID 16631354, PMID 16680620, PMID 16696824, PMID 16737798, PMID 16965196, PMID 17054789, PMID 17107245, PMID 17187495, PMID 17204397, PMID 17284127, PMID 17323327, PMID 17412850, PMID 17412856, PMID 17535948, PMID 17851042, PMID 17898352
P50MH119569 (4), K23DA050808 (2), R01DA013196 (2), R01MH077210 (2), R34MH111852 (2), R34MH129552 (2), 1RF1MH116987-01 (1), 2004 (1), 2005 (1), 2009 (1), 2015 (1), 2018 (1), I01RX000180 (1), K23DA018203 (1), K23MH077653 (1)