56 completed, 3 recruiting, 3 terminated, 3 unknown. 21 Phase 4, 15 Phase 3, 13 Phase 2, 7 Not applicable, 5 Phase 1.
Follow Raloxifene Hydrochloride: new trials by email Literature Review of Raloxifene Hydrochloride trials Research Report on Raloxifene Hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain Memantine, Raloxifene - Brain Tumor | Phase 2 | Recruiting | The University of Texas Health Science Center at San Antonio | 108 | 2026-07-06 | 2026-09-22 |
| New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia raloxifene, Finasteride - BPH (Benign Prostatic Hyperplasia), Lower Urinary Track Symptoms | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 242 | 2025-12-03 | 2026-03-23 |
| XCHT for Irinotecan-Induced Gut Toxicities (Randomized Controlled Trial) Xiao Chai Hu Tang (XCHT), Placebo, Irinotecan regimen - Xiao Chai Hu Tang, Irinotecan-induced Diarrhea | Not applicable | Recruiting | Guangzhou University of Traditional Chinese Medicine | 98 | 2024-03-08 | 2025-07-01 |
| XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study) Xiao Chai Hu Tang (XCHT), Raloxifene, FOLFIRI regimen - Malignant Tumor, Diarrhea | Not applicable | Completed | Guangzhou University of Traditional Chinese Medicine | 24 | 2021-07-16 | 2024-07-30 |
| Multicenter Double Blind, Parallel-group Phase 2/3 Trial, to Study Raloxifene in Adult COVID-19 Patients. Raloxifene, Placebo - SARS CoV 2 Infection | Phase 2 / Phase 3 | Completed | Dompé Farmaceutici S.p.A | 61 | 2021-01-22 | 2023-12-26 |
| Effect of Raloxifene Plus Cholecalciferol and Cholecalciferol Alone on the Bone Mineral Density in Postmenopausal Women With Osteopenia Raloxifene plus cholecalciferol, Cholecalciferol - Postemenopusal Women With Osteopenia | Phase 4 | Completed | Yonsei University | 112 | 2020-12-16 | 2024-04-17 |
| Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data Raloxifene, Zoledronic Acid - Osteoporosis | Completed | Brigham and Women's Hospital | 18028 | 2020-09-22 | 2023-07-27 | |
| Evaluating the Pharmacokinetic Characteristics of AD-102 in Healthy Volunteers Raloxifene 60mg/Cholecalciferol 800IU, AD-102 - Osteoporosis | Phase 1 | Completed | Addpharma Inc. | 52 | 2019-02-28 | 2019-08-30 |
| Evaluating the Pharmacokinetic Characteristics of AD-101 in Healthy Volunteers AD-101 45mg, Raloxifene 60mg - Osteoporosis | Phase 1 | Completed | Addpharma Inc. | 52 | 2018-12-14 | 2019-08-30 |
| Comparative Antiresorptive Efficacy Discontinuation of Denosumab denosumab, alendronate, raloxifene - Osteoporosis, Postmenopausal, Osteoporosis | Phase 4 | Active not recruiting | Massachusetts General Hospital | 51 | 2018-11-30 | 2023-06-07 |
| Adjunctive Selective Estrogen Receptor Modulators on Negative and Cognitive Symptoms of Schizophrenia in Women Raloxifene Hydrochloride, Placebo - Schizophrenia | Phase 4 | Completed | Shanghai Mental Health Center | 45 | 2018-07-17 | 2019-09-06 |
| Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery Bicalutamide, Laboratory Biomarker Analysis, Questionnaire Administration - Stage I Prostate Adenocarcinoma, Stage II Prostate Adenocarcinoma | Phase 2 | Withdrawn | Mayo Clinic | 2017-06-27 | 2019-01-22 | |
| DP-R213 Phase 1 Pharmacokinetics Study DP-R213, Raloxifene, Cholecaliferol - Healthy | Phase 1 | Completed | Alvogen Korea | 46 | 2017-01-03 | 2017-06-05 |
| Osteoporosis Treatment in Post-menopausal Women Raloxifene, Alendronate - Depressive Syndrome | Phase 4 | Unknown | Taichung Veterans General Hospital | 500 | 2017-01-01 | 2019-01-14 |
| Raloxifene Augmentation in Patients With a Schizophrenia Spectrum Disorder Raloxifene, Placebo - Schizophrenia, Schizoaffective Disorder | Phase 3 | Completed | Iris Sommer | 110 | 2016-08-01 | 2021-10-08 |
| DP-R213 Pharmacokinetics Study DP-R213, Raloxifene, Cholecaliferol - Healthy | Phase 1 | Completed | Alvogen Korea | 61 | 2016-05-01 | 2016-11-01 |
| A Drug-drug Interaction Study of DP-R213 Cholecalciferol, Raloxifene, Cholecalciferol and Raloxifene co-administration - Healthy | Phase 1 | Completed | Alvogen Korea | 24 | 2016-01-01 | 2016-03-11 |
| Clinical Trial on the Efficacy of Raloxifene on Disease Activity in Rheumatoid Arthritis Raloxifene hydrochloride, Placebo Oral Tablet - Rheumatoid Arthritis | Not applicable | Completed | Sara Saeidi Shahri | 34 | 2015-09-01 | 2021-12-16 |
| Efficacy Study of Raloxifene to Induce Ovulation in Polycystic Ovarian Syndrome Raloxifene, Clomiphene - Polycystic Ovarian Syndrome | Not applicable | Terminated | Bruce Lessey | 3 | 2012-06-01 | 2018-09-20 |
| Selective Estrogen Receptor Modulators (SERMs) - A Potential Treatment for Psychotic Symptoms of Schizophrenia in Men? Raloxifene Hydrochloride, Placebo - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | The Alfred | 13 | 2012-01-01 | 2023-11-28 |
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Osteoporosis (15) · Osteoporosis, Postmenopausal (12) · Schizophrenia (9) · Breast Neoplasms (7) · Psychotic Disorders (6) · Mental Disorders (5) · Alzheimer Disease (2) · Neoplasms (2) · Polycystic Ovary Syndrome (2) · Adenocarcinoma (1) · Anovulation (1) · Arthritis, Rheumatoid (1) · Bone Diseases, Metabolic (1) · Brain Neoplasms (1) · COVID-19 (1)
Eli Lilly and Company (11) · The Alfred (4) · Alvogen Korea (3) · Addpharma Inc. (2) · Fundació Sant Joan de Déu (2) · Guangzhou University of Traditional Chinese Medicine (2) · Mayo Clinic (2) · Pfizer (2) · University of Wisconsin, Madison (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · Bayer (1) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · Bruce Lessey (1) · Dompé Farmaceutici S.p.A (1)
United States (34) · Spain (7) · Australia (6) · Canada (5) · South Korea (5) · China (4) · Italy (4) · Netherlands (4) · France (3) · Mexico (3) · Taiwan (3) · Argentina (2) · Austria (2) · Brazil (2) · Germany (2)
Alec Walker, MD, DrPH (1) · Andrea Manni, MD (1) · Andrew J Brenner, MD, PhD (1) · Anna Schwartz, FNP, PhD (1) · Anthony Howell, MD (1) · Antonio Cano, MD (1) · Aria Olumi, MD (1) · Bob Oranje, Ass. Prof. (1) · Bruce A Lessey, MD, PhD (1) · Bruce A. Lessey, MD, PhD (1)
PMID 31415936, PMID 14693739, PMID 16235377, PMID 16754727, PMID 16754728, PMID 16837676, PMID 18165396, PMID 18583470, PMID 18838053, PMID 19105706, PMID 19204301, PMID 19213563, PMID 19584192, PMID 19635615, PMID 20404000, PMID 20927038, PMID 21145540, PMID 21187295, PMID 21775836, PMID 21782166, PMID 21796066, PMID 21880792, PMID 21903021, PMID 22318751, PMID 23335675, PMID 23481531, PMID 24342775, PMID 24619763, PMID 26591005, PMID 27438995, PMID 27676118, PMID 28145413, PMID 28541645, PMID 31728631, PMID 33470755, PMID 34984851, PMID 35582123, PMID 35585813, PMID 36247744, PMID 38939828, PMID 39112628, PMID 39129266
2015 (1), P30CA015083 (1), R01AG018198 (1), R01AG029624 (1), R01DK142211 (1), R13AG020218 (1), ZIAMH002537-26 (1)