201 completed, 66 unknown, 43 recruiting, 26 terminated. 387 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 387 | Completed 201, Unknown 66, Recruiting 43, Terminated 26, Not yet recruiting 20, Withdrawn 17, Active not recruiting 10, Enrolling by invitation 4 |
Follow Retinal Degeneration: new trials by email Literature Review of Retinal Degeneration trials Research Report on Retinal Degeneration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss Personalised Remapping Training, RSVP personalized remappi, Reading text in the wild with remapping - Macular Degeneration, Central Visual Impairment | Not applicable | Not yet recruiting | University of Minnesota | 216 | 2027-06-01 | 2026-10-29 |
| Safety and Clinical Performance of the LENTIS® MAX LS-313 MF80 Compared With the Monofocal L-313 in Cataract Patients With Late Age-Related Macular Degeneration: A Multicenter Comparative Clinical Investigation. Intraocular Lens - Cataract, AMD - Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Teleon Surgical B.V. | 35 | 2027-02-01 | 2026-11-04 |
| Non-invasive Ultrasound Retinal Stimulation for Vision Restoration Non-invasive ultrasound retinal stimulation Device - Age-Related Macular Degeneration, Retinitis Pigmentosa | Not applicable | Not yet recruiting | University of Southern California | 5 | 2027-01-10 | 2026-01-08 |
| Adaptive Optics Scanning Light Ophthalmoscopy (AOSLO) and Microperimetry (MP) Sub-study Adaptive Optics Scanning Light Ophthalmoscopy, Microperimetry, Optical Coherence Tomography - Geographic Atrophy | Not applicable | Enrolling by invitation | University of Wisconsin, Madison | 10 | 2026-11-05 | 2026-10-26 |
| MacuMira Microcurrent Stimulation for Dark Adaptation in Dry Age-Related Macular Degeneration Transpalpebral microcurrent electrical stimulation - Age-Related Macular Degeneration (AMD) | Not applicable | Not yet recruiting | Clarity Eye Institute | 50 | 2026-11-04 | 2026-11-04 |
| Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment Active hf-tRNS., Placebo/sham hf-tRNS - Retinitis Pigmentosa (RP), Rod Cone Dystrophy | Not applicable | Recruiting | University of Waterloo | 20 | 2026-11-01 | 2026-11-03 |
| Photobiomodulation Laser for Reticular Pseudodrusen in Age-Related Macular Degeneration Photobiomodulation Therapy, Sham Photobiomodulation - AMD - Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Fondazione G.B. Bietti, IRCCS | 67 | 2026-10-01 | 2026-09-04 |
| Natural History Study of Advanced RCD Eye examinations, Questionnaire - Rod Cone Dystrophy | Not applicable | Recruiting | SparingVision | 100 | 2026-09-11 | 2026-10-08 |
| Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center Animated Videos - Diabetic Retinopathy (DR), Macular Edema (ME) | Not applicable | Not yet recruiting | University of California, San Francisco | 150 | 2026-09-01 | 2026-07-22 |
| LEAP Strategy for Neovascular Age-Related Macular Degeneration Laser photocoagulation, Anti-VEGF agents - Neovascular Age-related Macular Degeneration(nAMD), Wet Macular Degeneration | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 240 | 2026-08-01 | 2026-08-19 |
| Pterygopalatine Ganglion Stimulation for the Treatment of Geographic Atrophy Pterygopalatine ganglion stimulation, Sham pterygopalatine ganglion stimulation - Geographic Atrophy | Not applicable | Not yet recruiting | Shanghai Institute of Acupuncture, Moxibustion and Meridian | 62 | 2026-06-01 | 2026-05-06 |
| Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension Low glycemic Mediterranean diet behavioral modification - Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Stanford University | 32 | 2026-06-01 | 2026-05-26 |
| Multicenter Study of Transcranial Magnetic Stimulation on Vision Restoration Transcranial magnetic stimulation targeting occipital visual cortex, Sham stimulation - Retinal Degeneration, Vision Impairment and Blindness | Not applicable | Not yet recruiting | Shanghai High Myopia Study Group | 136 | 2026-06-01 | 2026-02-23 |
| AI vs. Physician for Anti-VEGF Decision-Making: An RCT QiLin-assisted, physician only, without QiLin assisted - DME, Retinal Vein Occlusion (RVO) | Not applicable | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 200 | 2026-05-25 | 2026-05-22 |
| Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy Transcorneal electrical stimulation (TES) with the OkuStim 2 System - Geographic Atrophy Secondary to Age-related Macular Degeneration | Not applicable | Recruiting | Okuvision GmbH | 70 | 2026-05-05 | 2026-07-28 |
| Restoration of Central Vision With PRIMA in Patients With Photoreceptor Degeneration PRIMA Products - Stargardt Disease, Retinitis Pigmentosa (RP) | Not applicable | Recruiting | Science Corporation | 5 | 2026-04-22 | 2026-08-17 |
| Effectiveness of Multidisciplinary Protocolised Interventions on IVT Non-adherence Rates multidisciplinary protocolized intervention (MPI), Routine medical care & monitoring - Diabetic Macular Edema, Neovascular (Wet) Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Singapore Eye Research Institute | 200 | 2026-04-01 | 2026-05-05 |
| Validation of Virtual Reality Tests for the Assessment of Patients With Age-related Macular Degeneration as Clinical Endpoints Object recognition and selection task - Dry AMD, Geographic Atrophy | Not applicable | Not yet recruiting | Streetlab | 60 | 2026-04-01 | 2026-02-25 |
| High Resolution Imaging OCT Study Autofluorescence Imaging, Infrared reflectance imaging, OCT imaging - Normal Eyes, Age Related Macular Degeneration | Not applicable | Recruiting | Heidelberg Engineering GmbH | 97 | 2026-03-13 | 2026-08-26 |
| AI-Assisted Detection of Posterior Segment Diseases: DR, AMD, RVO, and Glaucoma VUNO Med-Fundus AI - Diabetic Retinopathy, Age Related Macular Degeneration | Not applicable | Completed | Inje University | 10 | 2026-02-20 | 2026-06-23 |
Showing 20 of 387. Sign in to see all of them.
Macular Degeneration (243) · Macular Edema (66) · Retinitis Pigmentosa (64) · Diabetic Retinopathy (38) · Geographic Atrophy (29) · Glaucoma (25) · Retinal Vein Occlusion (22) · Vision Disorders (21) · Cone-Rod Dystrophies (16) · Retinal Diseases (14) · Cataract (12) · Blindness (11) · Vision, Low (11) · Choroidal Neovascularization (10)
Eye Diseases (377) · Retinal Diseases (373) · Eye Diseases, Hereditary (92) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (78) · Genetic Diseases, Inborn (77) · Pathological Conditions, Signs and Symptoms (73) · Macular Degeneration (70) · Retinal Dystrophies (69) · Cardiovascular Diseases (61) · Vascular Diseases (61) · Nervous System Diseases (60) · Signs and Symptoms (53) · Neurologic Manifestations (51) · Endocrine System Diseases (48)
Ranibizumab (23) · Bevacizumab (9) · Lutein (9) · Calcium Dobesilate (8) · Zeaxanthins (8) · aflibercept (7) · Blood Specimen Collection (6) · Dexamethasone (6) · Vitrectomy (6) · Triamcinolone Acetonide (5) · Docosahexaenoic Acids (3) · Laser Therapy (3) · Lasers (3) · Lidocaine (3) · Low-Level Light Therapy (3)
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (10) · VisionCare, Inc. (9) · Medical University of Vienna (8) · Science Corporation (6) · Wills Eye (6) · Duke University (5) · Fondation Ophtalmologique Adolphe de Rothschild (5) · Center for Eye Research Australia (4) · Johns Hopkins University (4) · Okuvision GmbH (4) · Retina Implant AG (4) · Second Sight Medical Products (4) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (4) · University of California, San Francisco (4) · Ankara Universitesi Teknokent (3)
United States (107) · France (42) · Canada (22) · Italy (22) · China (20) · Germany (20) · United Kingdom (19) · Austria (16) · South Korea (11) · Spain (9) · Australia (8) · Belgium (6) · Hong Kong (6) · Netherlands (6) · Brazil (5)
Umut Arslan, MD (3) · Amitha Domalpally, MD, PhD (2) · Andrii MD Korol, PhD (2) · Ben Thompson, PhD (2) · Benjamin Thompson, PhD (2) · Christina I Frennesson, MD, PhD (2) · Dorte Nellemann Thornit, MD (2) · Florian Gekeler, Prof. Dr. (2) · Gaurav K Shah, MD (2) · Janet P Szlyk, PhD (2) · Jeffrey Weiss, MD (2) · Jens Dawczynski, MD (2)
PMID 37702300, PMID 21296824, PMID 22234714, PMID 22562517, PMID 24150759, PMID 25812924, PMID 26199618, PMID 26604914, PMID 27857759, PMID 27904503, PMID 28878616, PMID 32343050, PMID 32573764, PMID 12177445, PMID 12386035, PMID 12714656, PMID 15294883, PMID 16154196, PMID 16736131, PMID 18385097, PMID 18515576, PMID 18779718, PMID 19098313, PMID 19167079, PMID 19189118, PMID 19204228, PMID 19365014, PMID 19365036, PMID 19387076, PMID 19608533, PMID 19896746, PMID 19955196, PMID 20042642, PMID 20221623, PMID 20465801, PMID 20610478, PMID 20662848, PMID 20720224, PMID 20855114, PMID 20881025, PMID 21296811, PMID 21467183, PMID 21546089, PMID 21693599, PMID 21873668, PMID 22110084, PMID 22183994, PMID 22244176, PMID 22247465, PMID 22330964
2019 (1), I01RX004563 (1), R00EY029329 (1), R01AG059613 (1), R01EY021900 (1), R01EY022931 (1), R01EY029741 (1), R01EY029885 (1), R21DC019458 (1), R21EY023720 (1), R21EY033623 (1), R34EY035782 (1), R43EY025508 (1), R44EY018990 (1), R44EY028077 (1)