13 recruiting, 10 completed, 8 unknown, 4 active not recruiting. 16 Not applicable, 9 Phase 1, 9 Phase 2, 1 Phase 3.
Follow Cone-Rod Dystrophies: new trials by email Literature Review of Cone-Rod Dystrophies trials Research Report on Cone-Rod Dystrophies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Natural History Study of Advanced RCD Eye examinations, Questionnaire - Rod Cone Dystrophy | Not applicable | Recruiting | SparingVision | 100 | 2026-09-11 | 2026-10-08 |
| Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment Active hf-tRNS., Placebo/sham hf-tRNS - Retinitis Pigmentosa (RP), Rod Cone Dystrophy | Not applicable | Recruiting | University of Waterloo | 20 | 2026-07-01 | 2026-07-07 |
| Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance Transcorneal Electrical Stimulation using the OkuStim System - Retinitis Pigmentosa (RP), Usher Syndrome | Recruiting | Okuvision GmbH | 30 | 2026-04-20 | 2026-05-01 | |
| Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone Dystrophy SPVN20 (high dose), SPVN20 (medium dose), SPVN20 (low dose) - Retinitis Pigmentosa (RP), Rod Cone Dystrophy | Phase 1 / Phase 2 | Recruiting | SparingVision | 27 | 2025-10-08 | 2026-09-08 |
| Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients DF-003 - ROSAH | Phase 1 | Recruiting | Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm) | 12 | 2025-05-27 | 2026-06-05 |
| A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO) OpCT-001 - Primary Photoreceptor Disease, Retinitis Pigmentosa (RP) | Phase 1 / Phase 2 | Recruiting | BlueRock Therapeutics | 54 | 2025-03-10 | 2026-10-15 |
| Epidural Stimulation for Upper Extremity Function Percutaneous spinal cord stimulation - Spinal Cord Injury Cervical, Tetraplegia | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 20 | 2024-09-01 | 2024-05-31 |
| Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH) Prescreening Assessments - Stargardt Disease, Stargardt Disease 1 | Recruiting | Ascidian Therapeutics, Inc | 50 | 2024-06-20 | 2026-10-09 | |
| Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR) ACDN-01 - Stargardt Disease, Cone Rod Dystrophy | Phase 1 / Phase 2 | Recruiting | Ascidian Therapeutics, Inc | 15 | 2024-06-11 | 2026-10-07 |
| Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease VR Mobility Tool - Cone-Rod Degeneration, Rod-Cone Degeneration | Phase 1 | Recruiting | National Eye Institute (NEI) | 165 | 2023-07-25 | 2026-08-10 |
| Promising ROd-cone DYstrophy Gene therapY SPVN06 - Retinitis Pigmentosa | Phase 1 / Phase 2 | Active not recruiting | SparingVision | 33 | 2023-04-12 | 2026-05-15 |
| MNCs for Bone Marrow Failure After Malignant Diseases Children Chemotherapy Intravenous infusion of cord blood mononuclear cells, application of granulocyte stimulating factor - Cord | Not applicable | Unknown | Qianfoshan Hospital | 20 | 2022-10-01 | 2022-11-28 |
| Effect of Intraoperative Taping on the Control of Edema Resulting From Stripping Transoperative taping, No trasoperative taping - Edema, Varices; Cord | Not applicable | Unknown | University of Sao Paulo | 60 | 2022-10-01 | 2022-09-09 |
| Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity Motor Skill Training (MST), Transcutaneous Spinal Stimulation (TSS) - Incomplete Spinal Cord Injury, Spasticity, Muscle | Not applicable | Active not recruiting | Shepherd Center, Atlanta GA | 28 | 2022-03-01 | 2026-09-01 |
| Adaptive Optics Imaging of Outer Retinal Diseases Adaptive optics imaging - Retinal Degeneration, Age-Related Macular Degeneration | Recruiting | Food and Drug Administration (FDA) | 100 | 2021-08-27 | 2026-05-08 | |
| Mother to Child Transmission of Antibody to Covid-19 The TRAB CoV-19 Study. Antibody, Vaccine | Completed | National University of Malaysia | 197 | 2021-07-29 | 2022-04-08 | |
| Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] Gene Therapy Product-MCO-010, Sham Injection - Retinitis Pigmentosa, Retinitis | Phase 2 | Completed | Nanoscope Therapeutics Inc. | 27 | 2021-07-13 | 2024-03-22 |
| EyeConic: Qualification for Cone-Optogenetics Optical coherence tomography (OCT) - Retinal Dystrophies | Recruiting | Institute of Molecular and Clinical Ophthalmology Basel | 1000 | 2021-07-01 | 2025-07-31 | |
| Study of New Mutations in Cone Disorders Blood and/or skin biopsy - Retinal Dystrophy, Cone-Rod, Cone Dystrophy | Terminated | University Hospital, Lille | 7 | 2021-03-03 | 2026-05-22 | |
| Prospective Natural History Study of Retinitis Pigmentosa Ophthalmic examinations, Mobility Test - Retinitis Pigmentosa | Not applicable | Active not recruiting | SparingVision | 82 | 2020-02-12 | 2025-05-22 |
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Retinitis Pigmentosa (19) · Eye Diseases (9) · Retinal Diseases (9) · Retinal Dystrophies (9) · Retinal Degeneration (8) · Choroideremia (5) · Cone Dystrophy (5) · Stargardt Disease (5) · Usher Syndromes (5) · Macular Degeneration (4) · Blindness (3) · Eye Diseases, Hereditary (3) · Glaucoma (3) · Vision Disorders (3)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (39) · Genetic Diseases, Inborn (39) · Eye Diseases, Hereditary (36) · Retinal Degeneration (31) · Eye Diseases (30) · Retinal Diseases (30) · Retinal Dystrophies (30) · Nervous System Diseases (15) · Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (14) · Neurologic Manifestations (12) · Sensation Disorders (10) · Congenital Abnormalities (7) · Abnormalities, Multiple (6) · Ear Diseases (6)
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