63 completed, 5 terminated, 5 withdrawn, 4 unknown. 47 Not applicable, 9 Phase 2, 6 Phase 3, 6 Phase 4, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Preoperative Gas in Eyes With Macula-off Rhegmatogenous Retinal Detachment (RRD) Intravitreal 100% C3F8 Injection, Pars plana vitrectomy or pars plana vitrectomy with scleral buckle - Retinal Detachment Rhegmatogenous | Phase 2 / Phase 3 | Not yet recruiting | Wills Eye | 190 | 2026-09-21 | 2026-10-02 |
| Tebentafusp-tebn With LDT in Metastatic UM Tebentafusp-Tebn, GM-CSF (Sargramostim), BCNU - Metastatic Uveal Melanoma | Phase 1 / Phase 2 | Recruiting | Thomas Jefferson University | 109 | 2025-10-15 | 2026-07-21 |
| Electrical Stimulation for the Treatment of Glaucoma Repetitive, Transorbital Alternating Current Stimulation (rtACS), Sham Repetitive, Transorbital Alternating Current Stimulation (rtACS) - Glaucoma, Glaucoma, Open-Angle | Not applicable | Active not recruiting | Stanford University | 45 | 2023-02-28 | 2026-10-09 |
| A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Glycerin 0.2%/Hypromellose 0.2%/Peg 1%/Soln,Oph,Ud - Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy | Phase 2 / Phase 3 | Unknown | Wills Eye | 80 | 2023-02-06 | 2024-07-30 |
| Evaluating Home Testing Devices for the Management of Glaucoma Standard Automatic Perimetry Humphrey Field Analyzer, visuALL H, iCare Home Tonometer - Glaucoma, Open-Angle | Not applicable | Completed | Wills Eye | 53 | 2022-04-15 | 2026-08-20 |
| Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection. Use of bromfenac 0.09% to reduce intravitreal injection pain, Use of artificial tears to reduce intravitreal injection pain - Pain, Intravitreal Injection | Phase 4 | Completed | Wills Eye | 97 | 2021-03-01 | 2024-02-09 |
| Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin GlaucoCetin, Placebo - Primary Open Angle Glaucoma | Not applicable | Terminated | Wills Eye | 12 | 2021-02-01 | 2025-12-23 |
| Comparative Study of Sharkskin Versus Grieshaber Forceps During ILM Peeling Sharkskin, Grieshaber - Epiretinal Membrane, Macular Holes | Not applicable | Unknown | Wills Eye | 100 | 2020-07-06 | 2020-07-07 |
| IOP and Medication Reduction in MIGS Procedures Glaucoma and Cataract Surgery - Open Angle Glaucoma, Primary Open Angle Glaucoma | Not applicable | Withdrawn | Wills Eye | 2020-01-06 | 2021-02-21 | |
| CNGB1 and Allied Disorders No intervention, this is a natural history progression study - Retinitis Pigmentosa Associated With CNGB1 Mutations | Suspended | Columbia University | 20 | 2019-03-14 | 2026-04-13 | |
| RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa RETINA IMPLANT Alpha AMS - Retinitis Pigmentosa | Not applicable | Withdrawn | Wills Eye | 2019-03-01 | 2019-05-10 | |
| visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry Standard Automatic Perimetry Humphrey Field Analyzer, visuALL Field Analyzer - Glaucoma, Open-Angle | Not applicable | Completed | Wills Eye | 72 | 2019-01-08 | 2022-06-29 |
| Transcorneal Electrical Stimulation for the Treatment of Retinitis Pigmentosa - a Safety and Efficacy Multicenter Study Transcorneal Electrical Stimulation using Okustim device - Retinitis Pigmentosa | Not applicable | Withdrawn | Wills Eye | 2019-01-01 | 2019-05-01 | |
| Caffeine Consumption in Glaucoma Patients and Healthy Subjects Caffeine tablet - Glaucoma, Primary Open Angle | Not applicable | Completed | Wills Eye | 18 | 2018-12-30 | 2026-10-13 |
| Quality and Diagnostic Utility of Mydriatic Fundus Plenoptic Photography Lytro Plenoptic Camera and 28D lens - Retinal Imaging | Withdrawn | Wills Eye | 2018-12-01 | 2019-11-13 | ||
| Comparing Refractive and Visual Outcomes of MIGS and Traditional Surgeries Glaucoma, Ocular Hypertension | Unknown | Wills Eye | 150 | 2018-08-01 | 2022-03-29 | |
| Educational Intervention to Adopt SLT as First-Line Glaucoma Treatment Patient Educational Intervention, Usual Care, Ophthalmologist Educational Intervention - Primary Open-angle Glaucoma | Not applicable | Completed | Wills Eye | 86 | 2017-10-23 | 2020-01-30 |
| Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study Timolol Maleate, Brimonidine Tartrate - Glaucoma; Drugs, Normal Tension Glaucoma | Phase 4 | Completed | Wills Eye | 35 | 2017-07-10 | 2020-12-31 |
| Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections Handheld vibrator triggered during intravitreal injection for wet ARMD, Normal eye esthesiometry with and without vibration, Handheld vibrator not triggered during intravitreal injection for wet ARMD - Pain Control During Intravitreal Injections | Not applicable | Completed | Wills Eye | 110 | 2017-04-12 | 2019-05-09 |
| Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration Dorzolamide-timolol, Artificial tears - Neovascular Age-related Macular Degeneration, Wet Macular Degeneration | Phase 2 / Phase 3 | Completed | Wills Eye | 52 | 2017-02-08 | 2020-06-19 |
Showing 20 of 83. Sign in to see all of them.
Glaucoma (38) · Glaucoma, Open-Angle (16) · Macular Degeneration (6) · Diabetic Retinopathy (4) · Glaucoma, Angle-Closure (4) · Retinal Detachment (4) · Epiretinal Membrane (3) · Low Tension Glaucoma (3) · Retinal Vein Occlusion (3) · Retinitis Pigmentosa (3) · Vision Disorders (3) · Vitreoretinopathy, Proliferative (3) · Cataract (2) · Central Serous Chorioretinopathy (2) · Diabetes Mellitus (2)
Tomography, Optical Coherence (3) · Bevacizumab (2) · Evoked Potentials, Visual (2) · Hanks Balanced Salt Solution (2) · Lubricant Eye Drops (2) · Ranibizumab (2) · Timolol (2) · aflibercept (2) · dorzolamide-timolol combination (2) · Brimonidine Tartrate (1) · Caffeine (1) · Calcium Dobesilate (1) · Carboplatin (1) · Carmustine (1) · Cataract Extraction (1)
United States (73) · Germany (2) · Canada (1) · France (1) · United Kingdom (1)
George L Spaeth, MD (7) · Jason Hsu, MD (6) · L. Jay Katz, MD (4) · Daniel Lee, MD (3) · George Spaeth, MD (3) · Jonathan Myers, MD (3) · L J Katz, MD (3) · Leslie J Katz, MD (3) · Marlene R Moster, MD (3) · Mitchell Fineman, MD (3) · Allen Chiang, MD (2) · Jonathan S Myers, MD (2) · Julia Haller, MD (2) · M. Reza Razeghinejad, MD (2) · Ajay Kuriyan, MD (1)
PMID 40522203, PMID 18515577, PMID 18657796, PMID 20092592, PMID 22241927, PMID 22550394, PMID 22690120, PMID 23838767, PMID 24794283, PMID 24844543, PMID 25019269, PMID 25053760, PMID 25595177, PMID 25658175, PMID 25826644, PMID 26231376, PMID 26425961, PMID 26550975, PMID 26701273, PMID 26758536, PMID 26914218, PMID 26924099, PMID 27552513, PMID 28106888, PMID 28251085, PMID 28617732, PMID 28673747, PMID 29396688, PMID 29864044, PMID 30770354, PMID 32239190, PMID 32941320, PMID 34014814, PMID 34041935, PMID 39047125, PMID 42568743
R01EY013178 (1), U54NS065705 (1)