7 completed, 3 unknown, 2 active not recruiting, 2 terminated. 15 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 7, Unknown 3, Active not recruiting 2, Terminated 2, Not yet recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Renal Failure: new trials by email Literature Review of Renal Failure trials Research Report on Renal Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Renal Protection Of Dexmedetomidine Versus Midazolam As a Sedative For Septic Patients In Intensive Care Unit Midazolam, dexmedetomidine - Renal Failure | Phase 1 | Unknown | Minia University | 40 | 2023-05-22 | 2023-06-15 |
| Renal Allograft Tolerance Through Mixed Chimerism - SMC/MGH Rituximab, Fludarabine, Cyclophosphamide, Thymic irradiation and Siplizumab, Combined bone marrow and kidney transplant - Renal Failure | Phase 1 | Active not recruiting | Massachusetts General Hospital | 20 | 2021-09-01 | 2026-09-28 |
| A Study to Evaluate the Pharmacokinetics (Drug Levels and Metabolism), Safety, and Tolerability of BMS-986259 in Participants With Various Levels of Kidney Function BMS-986259 - Renal Failure | Phase 1 | Completed | Bristol-Myers Squibb | 30 | 2020-02-26 | 2021-09-24 |
| Pharmacokinetics in End Stage Renal Disease Patients firibastat - Healthy Volunteers, Renal Failure | Phase 1 | Completed | Quantum Genomics SA | 28 | 2019-09-17 | 2021-03-10 |
| Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions Amniotic and Umbilical Cord Tissue Procedure - Orthopedic Disorder, Neurologic Disorder | Phase 1 | Not yet recruiting | R3 Stem Cell | 5000 | 2019-09-01 | 2019-08-22 |
| A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function BMS-986231 - Myocardial Failure, Cardiac Failure | Phase 1 | Completed | Bristol-Myers Squibb | 48 | 2018-03-15 | 2019-09-11 |
| Pharmacokinetics of Lu AF35700 in Subjects With Renal Impairment Lu AF35700 - Renal Failure | Phase 1 | Terminated | H. Lundbeck A/S | 23 | 2017-07-25 | 2019-09-30 |
| Safety and TDM of Continuous Infusion Vancomycin Through Continuous Renal Replacement Therapy Solution Vancomycin - Pediatric Continuous Renal Replacement Therapy, Dialysis | Phase 1 | Unknown | Drexel University | 10 | 2017-01-01 | 2020-10-19 |
| Renal Function During Pediatric Anesthesia Sevoflurane, propofol - Renal Failure, Anesthesia | Phase 1 | Completed | Uppsala University | 24 | 2015-10-01 | 2020-11-04 |
| Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction Dabrafenib, Laboratory Biomarker Analysis, Pharmacogenomic Study - BRAF Gene Mutation, Hepatic Complication | Phase 1 | Terminated | National Cancer Institute (NCI) | 8 | 2013-08-23 | 2018-08-14 |
| Pharmacokinetic Profile and Pharmacodynamic Characteristics of a Furosemide High Dosage Formulation in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis FUROSEMIDE, FUROSEMIDE (HOE058) - Renal Failure | Phase 1 | Completed | Sanofi | 12 | 2012-11-01 | 2013-02-12 |
| Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Carboplatin, Laboratory Biomarker Analysis, Paclitaxel - Breast Carcinoma, Carcinoma of Unknown Primary | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 94 | 2011-06-20 | 2026-11-12 |
| A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function naproxcinod - Renal Failure | Phase 1 | Completed | NicOx | 32 | 2008-05-01 | 2009-01-28 |
| Pilot Study of Wearable Artificial Kidney Wearable artificial kidney - Renal Failure | Phase 1 | Completed | Royal Free Hampstead NHS Trust | 8 | 2007-03-01 | 2007-04-02 |
| Induction of Donor Specific Tolerance in Recipients of Live Donor Kidney Allografts by Donor Stem Cell Infusion Enriched Hematopoietic Stem Cell Infusion - Renal Failure | Phase 1 / Phase 2 | Unknown | Talaris Therapeutics Inc. | 38 | 2005-01-01 | 2022-07-18 |
Renal Insufficiency (15) · Alzheimer Disease (1) · Arthritis (1) · Autoimmune Diseases (1) · Breast Neoplasms (1) · Carcinoma, Transitional Cell (1) · Cardiomyopathies (1) · Cardiovascular Diseases (1) · Endometrial Neoplasms (1) · Erectile Dysfunction (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Heart Failure (1) · Kidney Diseases (1) · Liver Failure (1)
Female Urogenital Diseases (15) · Female Urogenital Diseases and Pregnancy Complications (15) · Male Urogenital Diseases (15) · Urogenital Diseases (15) · Kidney Diseases (14) · Urologic Diseases (14) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Chronic Disease (2) · Disease Attributes (2) · Genital Diseases (2) · Genital Diseases, Male (2) · Heart Diseases (2) · Respiratory Tract Diseases (2) · Adnexal Diseases (1)
Carboplatin (1) · Cyclophosphamide (1) · Dexmedetomidine (1) · Furosemide (1) · Kidney Transplantation (1) · Lu AF35700 (1) · Midazolam (1) · Paclitaxel (1) · Pharmacogenomic Testing (1) · Propofol (1) · Rituximab (1) · Sevoflurane (1) · Taxes (1) · Vancomycin (1) · dabrafenib (1)
Bristol-Myers Squibb (2) · National Cancer Institute (NCI) (2) · Drexel University (1) · H. Lundbeck A/S (1) · Massachusetts General Hospital (1) · Minia University (1) · NicOx (1) · Quantum Genomics SA (1) · R3 Stem Cell (1) · Royal Free Hampstead NHS Trust (1) · Sanofi (1) · Talaris Therapeutics Inc. (1) · Uppsala University (1)
United States (7) · Canada (2) · Czechia (1) · Egypt (1) · France (1) · Germany (1) · Poland (1) · Sweden (1) · United Kingdom (1)
David Greene, MD, MBA (1) · Hussein A Tawbi (1) · Jeffrey J Cies, PharmD, MPH (1) · Micael Taavo, MD (1) · Ramesh Ramanathan (1) · Suzanne T Ildstad, MD (1) · Victor Gurra, MD (1)
U01CA062490 (2), UM1CA186690 (2), UM1CA186691 (2), UM1CA186709 (2), UM1CA186716 (2), UM1CA186717 (2), 2019 (1), N01CM00100 (1), P30CA015083 (1), P30CA047904 (1), U01CA062502 (1), U01CA062505 (1), U01CA069856 (1), U01CA069912 (1), U01CA070095 (1)