70 completed, 17 unknown, 14 terminated, 11 active not recruiting. 37 Not applicable, 30 Phase 2, 25 Phase 1, 9 Phase 3, 6 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacogenomic Testing in Pediatric Hematology/Oncology Patients Pharmacogenomic Testing - Pediatric Cancer | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 130 | 2026-11-01 | 2026-09-25 |
| Biomarkers and Pharmacogenomics for Precision Depression Therapy Pharmacogenomic Testing, Antidepressant Agents - Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 220 | 2026-07-01 | 2026-07-31 |
| Evaluating Microarray Pharmacogenetic Testing in Cancer Patients Pharmacogenomic Testing with the "Global Diversity Array with Enhanced PGx" - Cancer, Gastrointestinal Cancer | Not applicable | Active not recruiting | Wake Forest University Health Sciences | 120 | 2025-07-18 | 2026-07-27 |
| Pharmacogenomics-Supported Psychotropic Prescribing Trial Pharmacogenetic Testing - Mental Disorder, Pharmacogenetics | Not applicable | Recruiting | University of Manitoba | 200 | 2025-07-01 | 2025-09-08 |
| PRE-EMPTIVE PHARMACOGENOMICS IN ACUTE CARE SETTINGS WITH HEALTH ECONOMIC EVALUATIONS (PHOENIX TRIAL) Pharmacogenomic testing - Pharmacogenomic Drug Interaction | Not applicable | Recruiting | NHS Greater Glasgow and Clyde | 2000 | 2025-04-09 | 2026-10-19 |
| Pharmacogenomic Informed Statin Prescribing Pharmacogenetic and polygenic risk testing, Active control - Hypercholesterolemia | Not applicable | Recruiting | VA Office of Research and Development | 214 | 2025-04-01 | 2026-11-02 |
| Informing Pain Treatment Using Pharmacogenomic Analysis Pharmacogenomic (PGx) results. - Adult Patients Who Are Receiving Oncologic Care | Not applicable | Recruiting | University of Chicago | 800 | 2024-07-30 | 2026-05-04 |
| Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer Pharmacogenetic testing, Drug-Drug interaction analysis - Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 600 | 2023-05-01 | 2025-07-09 | |
| Pharmacogenetic-guided Choice of Post-surgery Analgesics Pharmacogenetic testing, Pharmacist note with genotype-guided analgesic recommendations, Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines - Acute Pain, Post Operative Pain | Not applicable | Completed | University of Pennsylvania | 112 | 2022-10-13 | 2026-04-01 |
| The INTEGRATE Study: Integrated Pharmacogenetics, TDM and Active Pharmacovigilance as Innovative Tools for the Optimisation and Appropriateness of Drug Therapy Pharmacogenetics, TDM and MedReview - Adverse Drug Reaction (ADR) | Active not recruiting | Direzione centrale salute, politiche sociali e disabilità | 450 | 2022-06-10 | 2026-03-12 | |
| Clinical One-stage Controlled Study of reSistant Arterial Hypertension for the desiGning of a personAlized Approach to Therapy Blood samples will be taken for pharmacokinetics and pharmacogenetics - Resistant Arterial Hypertension | Not applicable | Unknown | Ryazan State Medical University | 190 | 2022-03-11 | 2024-04-24 |
| Pharmacogenomic Testing in a Program of All-inclusive Care for the Elderly (PACE) Setting Pharmacogenomic Testing - Pharmacogenomics, Polypharmacy | Unknown | Tabula Rasa HealthCare | 1500 | 2021-11-02 | 2022-09-02 | |
| Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans Pharmacogenomic Screening - Pharmacogenetics, Depressive Disorder, Major | Not applicable | Withdrawn | Auburn University | 2021-09-01 | 2022-08-09 | |
| A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial) Pharmacogenetic testing, Clinical decisions support - Depression | Not applicable | Completed | Duke University | 1572 | 2021-08-10 | 2025-06-29 |
| Implementation of a Pharmacist-led Pharmacogenomic Clinical Service Pharmacogenomic Testing - Adverse Drug Event, Drug Drug Interaction | Withdrawn | Tabula Rasa HealthCare | 2021-07-01 | 2023-02-01 | ||
| A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial) Pharmacogenetic testing, Clinical decisions support - Acute Pain | Not applicable | Completed | Duke University | 1602 | 2021-03-10 | 2026-03-19 |
| A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Chronic Pain Trial) Pharmacogenetic testing, Clinical decisions support - Chronic Pain | Not applicable | Completed | Duke University | 1048 | 2021-02-24 | 2025-05-28 |
| A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) Pharmacogenetic testing, Clinical decisions support - Depression, Acute Pain | Not applicable | Completed | Duke University | 4284 | 2021-02-24 | 2026-03-25 |
| Pharmacogenetic Supported Prescribing in Kids Pharmacogenetic Testing - Mental Health Impairment | Not applicable | Active not recruiting | University of Calgary | 6000 | 2021-01-18 | 2026-05-12 |
| Pharmacogenomics Applied to Chronic Pain Treatment in Primary Care Pharmacogenetic Testing, Pharmacist Consultation Note, Delayed pharmacogenetic testing - Chronic Pain | Not applicable | Unknown | Medstar Health Research Institute | 315 | 2020-12-02 | 2024-03-26 |
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Depression (13) · Breast Neoplasms (10) · Drug-Related Side Effects and Adverse Reactions (8) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Depressive Disorder, Major (6) · Lymphoma, B-Cell, Marginal Zone (6) · Lymphoma, Mantle-Cell (6) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Colorectal Neoplasms (5) · Lymphoma, Follicular (5) · Lymphoma, Large B-Cell, Diffuse (5) · Lymphoma, Non-Hodgkin (5) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (5) · Psychological Well-Being (5) · Anxiety Disorders (4)
National Cancer Institute (NCI) (22) · Mayo Clinic (6) · Avera McKennan Hospital & University Health Center (5) · Duke University (5) · University of Chicago (4) · Wake Forest University Health Sciences (4) · Children's Oncology Group (3) · University of Nebraska (3) · Case Comprehensive Cancer Center (2) · City of Hope Medical Center (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Genelex Corporation (2) · Institut Cancerologie de l'Ouest (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · Tabula Rasa HealthCare (2)
United States (79) · France (11) · Canada (9) · United Kingdom (8) · Belgium (3) · Italy (3) · Australia (2) · China (2) · Egypt (2) · Greece (2) · Netherlands (2) · Russia (2) · Singapore (2) · Slovenia (2) · Spain (2)
Hrishikesh Chakraborty (4) · Patricia LoRusso (3) · Hedy Kindler (2) · Jai Patel, PharmD (2) · James N. Ingle, MD (2) · Matthew Stanley, MD (2) · Todd Skaar, PhD (2) · Abdullah Al Maruf, PhD, M.Pharm., B.Pharm (1) · Adil Bharucha, MBBS, MD (1) · Adriana M Calvo, PhD (1) · Alison Quinn, PharmD (1) · Alvaro Pereira (1) · Amir Mortazavi, MD (1) · An Pang Chieng, MD (1) · Andrea E Wahner Hendrickson (1)
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P30CA015083 (5), P30CA022453 (3), U01CA062487 (3), U01HG010225 (3), UM1CA186686 (3), UM1CA186690 (3), UM1CA186691 (3), UM1CA186717 (3), N01CM62201 (2), P30CA014599 (2), P30CA016058 (2), P30CA036727 (2), U01CA062490 (2), U01CA069912 (2), U01CA070095 (2)