4582 completed, 1267 recruiting, 1161 unknown, 758 terminated. 2797 Not applicable, 2332 Phase 2, 1329 Phase 1, 911 Phase 3, 396 Phase 4.
Follow Genital Diseases, Male: new trials by email Literature Review of Genital Diseases, Male trials Research Report on Genital Diseases, Male
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria (a) Training and (b) Supported risk assessment - Prostate Cancer, Risk Assessment | Not applicable | Not yet recruiting | Ahmadu Bello University | 89 | 2029-03-01 | 2026-07-29 |
| A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy 177Lu-PSMA-I&T - escalating renal absorbed dose, 177Lu-PSMA-I&T - recommended phase 2 regime - Cancer, Prostate Cancer | Phase 1 / Phase 2 | Not yet recruiting | CHU de Quebec-Universite Laval | 500 | 2028-03-01 | 2025-03-30 |
| Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 / Phase 3 | Not yet recruiting | VA Office of Research and Development | 300 | 2027-10-01 | 2026-08-04 |
| REGN21353 Alone or in Combination With Nezastomig for Metastatic Castration-Resistant Prostate Cancer in Adult Participants REGN21353, Nezastomig, Sarilumab Prophylaxis (Contingency) - Metastatic Castration-Resistant Prostate Cancer, mCRPC | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 192 | 2027-06-28 | 2026-09-30 |
| Understanding the Role of MyCareGorithm as a Visual Digital Platforms in Cancer Treatment Education and Patient Comprehension of Oncology Treatment Plans Survey - Head and Neck Cancer, Prostate Cancer | Not applicable | Not yet recruiting | M.D. Anderson Cancer Center | 94 | 2027-03-01 | 2026-10-01 |
| Recover@Home Postoperative Follow-up Study Recovery@home - Hernia, Inguinal, Hernia, Femoral | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 194 | 2027-03-01 | 2026-07-20 |
| Prostate Stereotactic Radiation and Radio-induced Lymphocyte Apoptosis for Predicting Late Toxicities in Prostate Cancer (PROSTERA) Radio-induced Lymphocyte Apoptosis (RILA) Assay, Stereotactic body radiotherapy (SBRT) - Prostate Cancer | Not applicable | Not yet recruiting | Clinique Sainte Clotilde | 220 | 2027-02-01 | 2026-10-26 |
| iCCARE Project #4: Grounded Theory Study of the Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant Men Diagnosed With Prostate Cancer Interviews - Prostate Cancer | Not applicable | Not yet recruiting | M.D. Anderson Cancer Center | 40 | 2027-01-31 | 2026-10-06 |
| HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer Clomiphene Citrate 25mg - Prostate Cancer | Phase 2 | Not yet recruiting | University of Nebraska | 83 | 2027-01-31 | 2026-10-20 |
| Quality and Safety of Real-Time Brachytherapy Treatments: Clinical Implementation of a Multipoint Scintillation Detector for Treatment Monitoring Brachytherapy treatment monitoring using a plastic scintillation detector - Prostate Cancer, Gynecologic Cancers | Not applicable | Not yet recruiting | CISSS de Chaudière-Appalaches | 25 | 2027-01-15 | 2026-10-21 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Helping Young People With Testicular Cancer Using Virtual and Extended Reality Digital tool using extended reality - Testicular Cancer, Testis Cancer | Not applicable | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 245 | 2027-01-04 | 2026-05-06 |
| Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening Veteran Peer Decision Coaching Session for PSA Screening - Prostate Cancer | Not applicable | Not yet recruiting | VA Office of Research and Development | 228 | 2027-01-04 | 2026-10-21 |
| ALSO-PERFORM Study. ALternating Stereotaxic Or PElvic Radiotherapy FOR Metachronic Metastatic Prostate Cancer Prostate Cancer | Not yet recruiting | Amsterdam UMC, location VUmc | 130 | 2027-01-01 | 2026-10-08 | |
| Pilot Feasibility Study of a Dyadic Culinary Nutrition Intervention Cooking Healthy - Engaging Families (CHEF), Control - Neoplams, Prostate Cancer (Adenocarcinoma) | Not applicable | Not yet recruiting | University of Arizona | 40 | 2027-01-01 | 2026-07-14 |
| Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care ICG-Guided Retroperitoneal Sentinel Lymph Node Biopsy, Radical Inguinal Orchiectomy - Testicular Cancer, Testicular Germ Cell Tumor | Not applicable | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 171 | 2027-01-01 | 2026-07-13 |
| Weekly Online CT or MR Adaptive Definitive SBRT for Regionally Metastatic Prostate Cancer weekly CT or MR online adaptive definitive SBRT - Prostate Cancer | Not applicable | Not yet recruiting | University of Zurich | 54 | 2027-01-01 | 2026-08-21 |
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer Biopsy Procedure, Computed Tomography, Electronic Health Record Review - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-01-01 | 2026-08-17 |
| Investigation of an Intelligent Centre-adaptive Multi-modal Fusion Framework (Cad- MMFF) to Overcome Unnecessary Prostate Biopsies and Optimize MRI Utilization Prostate Cancer (Diagnosis) | Not yet recruiting | Chinese University of Hong Kong | 400 | 2027-01-01 | 2026-10-22 | |
| Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora Autologous tissue engineered corpora - Urologic Diseases, Male Urogenital Diseases | Phase 1 | Not yet recruiting | Wake Forest University Health Sciences | 10 | 2027-01-01 | 2026-10-23 |
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Prostatic Neoplasms (6446) · Prostatic Hyperplasia (809) · Erectile Dysfunction (670) · Breast Neoplasms (624) · Neoplasms (463) · Ovarian Neoplasms (302) · Testicular Neoplasms (295) · Infertility, Male (277) · Lung Neoplasms (269) · Neoplasm Metastasis (264) · Colorectal Neoplasms (254) · Urinary Bladder Neoplasms (218) · Pancreatic Neoplasms (204) · Carcinoma, Non-Small-Cell Lung (183) · Lower Urinary Tract Symptoms (165)
Genital Diseases (9216) · Urogenital Diseases (9212) · Male Urogenital Diseases (9199) · Prostatic Diseases (7242) · Neoplasms by Site (6853) · Genital Neoplasms, Male (6797) · Urogenital Neoplasms (6796) · Neoplasms (6435) · Pathological Conditions, Signs and Symptoms (1304) · Female Urogenital Diseases and Pregnancy Complications (1267) · Female Urogenital Diseases (1257) · Mental Disorders (994) · Sexual Dysfunctions, Psychological (887) · Sexual Dysfunction, Physiological (847)
Docetaxel (309) · Prednisone (256) · enzalutamide (218) · Leuprolide (191) · Radiotherapy (190) · Abiraterone Acetate (182) · Magnetic Resonance Spectroscopy (175) · bicalutamide (143) · Goserelin (142) · Androgen Antagonists (130) · Radiosurgery (113) · Tadalafil (113) · acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide (111) · apalutamide (99) · abiraterone (92)
National Cancer Institute (NCI) (221) · Memorial Sloan Kettering Cancer Center (151) · M.D. Anderson Cancer Center (130) · University Health Network, Toronto (102) · Bayer (101) · Mayo Clinic (83) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (73) · AstraZeneca (70) · Jonsson Comprehensive Cancer Center (70) · GlaxoSmithKline (68) · University of California, San Francisco (64) · Eli Lilly and Company (60) · Novartis Pharmaceuticals (59) · Dana-Farber Cancer Institute (58) · Janssen Research & Development, LLC (52)
United States (4170) · Canada (814) · France (610) · China (560) · United Kingdom (549) · Italy (435) · Spain (391) · Germany (382) · Netherlands (325) · South Korea (302) · Australia (282) · Belgium (269) · Egypt (236) · Turkey (Türkiye) (233) · Denmark (208)
Rahul Aggarwal, MD (17) · Chi Fai NG, MD (16)
PMID 34350976, PMID 24722180, PMID 33270906, PMID 41698328, PMID 21059176, PMID 25974235, PMID 33465252, PMID 35506389, PMID 36884035, PMID 38421243, PMID 38421252, PMID 22894553, PMID 24119319, PMID 25712310, PMID 25819287, PMID 27626136, PMID 29272162, PMID 32994091, PMID 37070660, PMID 38320143, PMID 22747660, PMID 25592642, PMID 25613154, PMID 26299520, PMID 27626365, PMID 28892218, PMID 40016438, PMID 20818327, PMID 21106711, PMID 21420124, PMID 22129214, PMID 22225814, PMID 22932804, PMID 23035781, PMID 24423462, PMID 24972732, PMID 25614256, PMID 25626035, PMID 25687533, PMID 25754526, PMID 26512712, PMID 27044935, PMID 27339115, PMID 29240541, PMID 29873008, PMID 30677455, PMID 31227373, PMID 31375469, PMID 31540791, PMID 32203306
2023 (48), 2017 (27), P30CA014089 (27), 2025 (25), P30CA033572 (25), 2016 (24), 2019 (24), P30CA072720 (21), U10CA031946 (20), 2008 (19), 2014 (19), P30CA008748 (16), P30CA016672 (16), P30CA022453 (16), 2018 (15)