31 completed, 21 unknown, 6 recruiting, 3 terminated. 67 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 67 | Completed 31, Unknown 21, Recruiting 6, Terminated 3, Withdrawn 3, Suspended 2, Enrolling by invitation 1 |
Follow Quality of Life: new trials by email Literature Review of Quality of Life trials Research Report on Quality of Life
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) Trazodone, Quetiapine, Placebo - Delirium, Morality | Phase 4 | Withdrawn | University of Southern California | 2028-03-01 | 2026-05-04 | |
| PeRiOperative Medicine Platform Trial Liberal inspired oxygen, Conservative inspired oxygen, Intermediate inspired oxygen - Surgical Site Infection After Major Surgery, Anaesthesia | Phase 4 | Recruiting | Monash University | 7800 | 2026-04-06 | 2026-04-17 |
| The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study Dexamethasone (IV) - Postoperative Quality of Recovery, Health-Related Quality-of-Life | Phase 4 | Recruiting | Ziekenhuis Oost-Limburg | 224 | 2026-01-30 | 2026-04-08 |
| The Effect of Different Types of Mouthwash on Extraction Sockets' Healing Chlorhexidine Gluconate, Bone Bioactive Liquid, Hyaluronic Acid mouthwash - Extraction Socket Healing, Quality of Life | Phase 4 | Recruiting | University of Jordan | 100 | 2025-08-10 | 2026-05-07 |
| PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study Elonva®, Puregon®, Orgalutran® - Ovarian Stimulation, Quality of Life | Phase 4 | Recruiting | University Hospital, Ghent | 60 | 2025-01-27 | 2025-12-26 |
| A Multimodal Intervention Program to Improve Sexual Health and Self-perceived Quality of Life in Patients Treated for Cervical Cancer (PROVIDENCE) Multimodal intervention on sexual dysfunction and quality-of-life - Cervical Cancer, Sexual Dysfunction | Phase 4 | Unknown | Hospital Clinic of Barcelona | 122 | 2025-01-01 | 2024-02-28 |
| Efficacy of 0.28% Sodium Hyaluronate Eye Drops in Patient With Moderate to Severe Dry Eye 0.28% Sodium Hyaluronate , preservative free eye drops, 0.18% Sodium Hyaluronate , preservative free eye drops - Dry Eye Disease (DED), Tear Break-Up Time | Phase 4 | Enrolling by invitation | Department of Medical Services Ministry of Public Health of Thailand | 84 | 2024-09-01 | 2025-03-06 |
| Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women vaginal 17 beta-estradiol, Placebo, Behavioral modifications - Lower Urinary Tract Symptoms, Female Genitourinary Disease | Phase 4 | Completed | Mahidol University | 86 | 2024-04-08 | 2025-04-20 |
| Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis Sodium Hyaluronate, Normal Saline, Triamcinolone Acetonide 10mg/mL - Knee Osteoarthritis, Pain, Joint | Phase 4 | Unknown | Phramongkutklao College of Medicine and Hospital | 176 | 2024-02-10 | 2024-02-28 |
| Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft Ibuprofen 600 mg, Placebo, Acetaminophen - Pain, Post Operative, Quality of Life | Phase 4 | Recruiting | Marquette University | 50 | 2023-10-19 | 2024-09-27 |
| Effects of Melissa Extract on Sleep Characteristics Melissa phytosome, Placebo - Sleep Disorder, Anxiety | Phase 4 | Unknown | University of Urbino "Carlo Bo" | 40 | 2023-09-01 | 2023-07-18 |
| Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity Bariatric surgery, Medical weight loss - Dyspnea, Quality of Life | Phase 4 | Withdrawn | University of California, Los Angeles | 2023-07-09 | 2025-02-14 | |
| Clinical Study on the Effect of Brucea Javanica Oil Emulsion Injection on the Survival of Patients With Advanced Colorectal Cancer Who Failed to Receive Multi-line Treatment Brucea javanica oil emulsion injection, The best supportive treatment - Colorectal Cancer, Chinese Herbal Medicine | Phase 4 | Unknown | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 60 | 2023-06-16 | 2023-06-09 |
| Quality of Recovery in Parturients Consumed Preoperative Carbohydrate Fluid for Elective Cesarean Delivery Carbohydrate, Placebo - Quality of Life, Breastfeeding | Phase 4 | Completed | Karamanoğlu Mehmetbey University | 100 | 2023-05-12 | 2024-03-19 |
| Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis Branched-chain Amino Acid, Placebo - Muscle Cramp, Cirrhosis | Phase 4 | Completed | Mahidol University | 48 | 2023-04-01 | 2024-02-09 |
| Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function Rocuronium Bromide - Neuromuscular Blockade, Innate Inflammatory Response | Phase 4 | Completed | Radboud University Medical Center | 100 | 2022-11-18 | 2024-09-19 |
| The Efficacy of Tamsulosin and Tadalafil Compared to Placebo in the Treatment and Prevention of Urinary Disorders After Transperineal Prostate Biopsy Tadalafil 5mg, Tamsulosin Hydrochloride 400 Microgram Prolonged-Release Oral Capsule, Placebo - Lower Urinary Tract Symptoms, Voiding Disorders | Phase 4 | Unknown | University Hospital of Split | 120 | 2022-09-01 | 2023-02-22 |
| 3D Evaluation of Postoperative Edema After Third Molar Surgery Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan) - Molar, Third, Third Molar Surgery | Phase 4 | Unknown | Implantology Institute | 40 | 2022-07-01 | 2023-07-12 |
| Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish - Early Childhood Caries, Dental Caries in Children | Phase 4 | Unknown | Universiti Sains Malaysia | 72 | 2022-01-18 | 2023-03-16 |
| Simultaneous mRNA COVID-19 and IIV4 Vaccination Study mRNA COVID-19, IIV4, Placebo (saline) - Quality of Life, Injection Site Reaction | Phase 4 | Completed | Duke University | 348 | 2021-10-04 | 2024-03-19 |
Showing 20 of 67. Sign in to see all of them.
Pain (5) · Pain, Postoperative (5) · Drug-Related Side Effects and Adverse Reactions (4) · Inflammation (4) · Pulmonary Disease, Chronic Obstructive (4) · Sexual Dysfunction, Physiological (4) · Agnosia (3) · Depression (3) · Influenza, Human (3) · Injection Site Reaction (3) · Multiple Endocrine Neoplasia Type 1 (3) · Obesity (3) · Anxiety Disorders (2) · Bronchiectasis (2) · HIV Infections (2)
Pathological Conditions, Signs and Symptoms (36) · Signs and Symptoms (24) · Pathologic Processes (22) · Neurologic Manifestations (18) · Respiratory Tract Diseases (11) · Urogenital Diseases (11) · Behavior (9) · Endocrine System Diseases (9) · Genital Diseases (9) · Nervous System Diseases (8) · Neoplasms (7) · Neoplasms by Site (7) · Pain (7) · Female Urogenital Diseases and Pregnancy Complications (6) · Lung Diseases (6)
Quality of Life (4) · Sodium Chloride (3) · Analgesia, Epidural (2) · Anesthesia, Epidural (2) · Anesthesia, General (2) · Botulinum Toxins, Type A (2) · Budesonide (2) · Budesonide, Formoterol Fumarate Drug Combination (2) · Dexamethasone (2) · Hyaluronic Acid (2) · Ibuprofen (2) · Influenza Vaccines (2) · Morphine (2) · Ropivacaine (2) · 2019-nCoV Vaccine mRNA-1273 (1)
Changi General Hospital (3) · Duke University (3) · University Hospital of Split (3) · Grupo de Investigação em Bioquímica e Biologia Oral (2) · Mahidol University (2) · Mansoura University (2) · Shanghai University of Traditional Chinese Medicine (2) · Zhujiang Hospital (2) · Assaf-Harofeh Medical Center (1) · Azienda Ospedaliera San Gerardo di Monza (1) · Boehringer Ingelheim (1) · Chulabhorn Cancer Center (1) · Copenhagen University Hospital at Herlev (1) · Cukurova University (1) · Department of Medical Services Ministry of Public Health of Thailand (1)
United States (10) · China (5) · Thailand (5) · Brazil (4) · Italy (4) · Croatia (3) · Denmark (3) · Singapore (3) · Turkey (Türkiye) (3) · Belgium (2) · Egypt (2) · Israel (2) · Pakistan (2) · Portugal (2) · Taiwan (2)
Bozidar Duplancic (2) · Hrvoje Vucemilovic (2) · Huapeng Yu (2) · Ivan Velat (2) · Ivo Juginovic (2) · Kenneth Schmader, MD (2) · Ruben Kovac (2) · Svjetlana Dosenovic (2) · Abdullah AlAlwani, DDS (1) · Ahmad Hamdan, Ph.D. in Periodontics (1) · Ahmed R EL-Nahas, MD (1) · Anas Imran Arshad, MSc., BDS (1) · Andrea Gori, MD (1) · Asgeir Sigurdsson (1)
PMID 10403745, PMID 11208726, PMID 11696744, PMID 12075033, PMID 12140209, PMID 12806613, PMID 12924658, PMID 12963433, PMID 14508260, PMID 14665353, PMID 14723108, PMID 15082703, PMID 15222044, PMID 15817019, PMID 1593914, PMID 15976462, PMID 16206505, PMID 16900272, PMID 16973668, PMID 17132474, PMID 17172891, PMID 17187655, PMID 17234504, PMID 17387740, PMID 17678782, PMID 17913605, PMID 17983434, PMID 18691081, PMID 19034126, PMID 19347026, PMID 19447919, PMID 19570764, PMID 19687169, PMID 19865006, PMID 21398686, PMID 21529354, PMID 21563202, PMID 21697993, PMID 21926597, PMID 22301509, PMID 22825550, PMID 22835465, PMID 23101012, PMID 23182527, PMID 23506796, PMID 23542334, PMID 23635309, PMID 23816815, PMID 23876588, PMID 24942957
2025 (2), 2019 (1), 2023 (1)