Pulmonary Disease, Chronic Obstructive: Clinical Trials

16 trials for Pulmonary Disease, Chronic Obstructive, newest first

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16 withdrawn. 16 Phase 2, 5 Phase 1, 2 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 216Withdrawn 16
Phase 15Withdrawn 5
Phase 32Withdrawn 2

Follow Pulmonary Disease, Chronic Obstructive: new trials by email Literature Review of Pulmonary Disease, Chronic Obstructive trials Research Report on Pulmonary Disease, Chronic Obstructive

Trials (filtered) newest first · largest first

All 16 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
Biospecimen Collection, Bronchial Brush Biopsy, Bronchoscopy - Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease
Phase 2WithdrawnNational Cancer Institute (NCI)2024-06-012024-05-17
Tiotropium Handihaler vs. Tiotropium Respimat in COPD
tiotropium bromide inhalation powder (Spiriva HandiHaler), tiotropium bromide (Spiriva Respimat), Hyperpolarized 129XeMRI - Chronic Obstructive Pulmonary Disease (COPD)
Phase 2WithdrawnDuke University2023-05-012023-06-15
The Multicenter Topic Trial
Ivacaftor - Chronic Obstructive Pulmonary Disease
Phase 2WithdrawnUniversity of Alabama at Birmingham2021-12-012022-01-27
Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD
Testosterone Enanthate, Placebo - COPD
Phase 2 / Phase 3WithdrawnThe University of Texas Medical Branch, Galveston2021-12-012022-02-02
Accessing Mobility Using Wearable Sensors
Exercise - COPD, Pulmonary Disease
Phase 1 / Phase 2WithdrawnBaylor College of Medicine2018-05-212025-08-27
Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD
Inhaled Treprostinil - Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
Phase 2WithdrawnUnited Therapeutics2017-04-012017-04-11
A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease
Tiotropium HFA BAI 5 mcg, Tiotropium 18 mcg Capsule, Placebo - Chronic Obstructive Pulmonary Disease, COPD
Phase 2WithdrawnTeva Branded Pharmaceutical Products R&D, Inc.2014-08-012021-11-09
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
Lipoaspiration with Local anesthesia - Chronic Obstructive Pulmonary Disease
Phase 1 / Phase 2WithdrawnAgeless Regenerative Institute2014-03-012017-11-24
Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema
Mesenchymal stem cells, Reference therapy: 400 mL of 0.9% NaCl solution - Pulmonary Emphysema
Phase 1 / Phase 2WithdrawnFederal Research Clinical Center of Federal Medical & Biological Agency, Russia2014-03-012018-01-09
Safety Study of Nebivolol for COPD Patients
Placebo, Nebivolol - High Blood Pressure
Phase 2 / Phase 3WithdrawnUniversity of Chicago2012-01-012016-01-12
Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)
Bi-level positive airway pressure (BPAP), Oxygen, CPAP - Chronic Obstructive Airway Disease
Phase 1 / Phase 2WithdrawnBrigham and Women's Hospital2010-11-012017-01-12
Effect of an Inhaled Glucocorticoid-long-acting Beta Adrenergic Agonist on Endothelial Function in COPD
Placebo, Fluticasone /salmeterol - COPD
Phase 2WithdrawnUniversity of Miami2010-10-012014-08-01
Efficacy and Safety of Two Doses of Formoterol Fumarate MDI (PT005) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), Compared to Foradil® Aerolizer® as an Active Control
Inhaled PT005, Inhaled Placebo, Formoterol Fumarate 12 µg (Foradil Aerolizer) - COPD
Phase 2WithdrawnPearl Therapeutics, Inc.2010-07-012014-07-11
Exploratory Study of Xolair in Chronic Obstructive Pulmonary Disease in Patients With Elevated IgE Levels
Omalizumab (Xolair), Placebo - Pulmonary Disease, Chronic Obstructive
Phase 2WithdrawnNational Jewish Health2009-01-012017-03-29
Safety and Efficacy of 4-weeks Treatment of BIBW 2948 BS in Patients With Chronic Obstructive Bronchitis
BIBW 2948 BS - Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic
Phase 2WithdrawnBoehringer Ingelheim2008-08-012014-03-27
A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD
mannitol - COPD, Exacerbation
Phase 1 / Phase 2WithdrawnSyntara2006-10-012016-09-28

Narrower conditions

Bronchitis, Chronic (1)  ·  Cardiovascular Diseases (1)  ·  Emphysema (1)  ·  Heart Failure (1)  ·  Hypertension (1)  ·  Hypertension, Pulmonary (1)  ·  Hypoxia (1)  ·  Lung Diseases (1)  ·  Lung Neoplasms (1)  ·  Microcephaly, Primary Autosomal Recessive, 6 (1)  ·  Pulmonary Emphysema (1)  ·  Sleep Apnea, Obstructive (1)

Broader conditions

Chronic Disease (16)  ·  Disease Attributes (16)  ·  Lung Diseases, Obstructive (16)  ·  Pathologic Processes (16)  ·  Pathological Conditions, Signs and Symptoms (16)  ·  Respiratory Tract Diseases (16)  ·  Lung Diseases (15)  ·  Cardiovascular Diseases (2)  ·  Vascular Diseases (2)  ·  Apnea (1)  ·  Bronchial Diseases (1)  ·  Bronchitis (1)  ·  Dyssomnias (1)  ·  Heart Diseases (1)  ·  Hypertension (1)

Interventions

Tiotropium Bromide (2)  ·  Anesthesia, Local (1)  ·  Bronchoscopy (1)  ·  Exercise (1)  ·  Fluticasone-Salmeterol Drug Combination (1)  ·  Formoterol Fumarate (1)  ·  Iloprost (1)  ·  Lipectomy (1)  ·  Mannitol (1)  ·  Nebivolol (1)  ·  Omalizumab (1)  ·  Oxygen (1)  ·  Specimen Handling (1)  ·  Telerehabilitation (1)  ·  ivacaftor (1)

Sponsors

Ageless Regenerative Institute (1)  ·  Baylor College of Medicine (1)  ·  Boehringer Ingelheim (1)  ·  Brigham and Women's Hospital (1)  ·  Duke University (1)  ·  Federal Research Clinical Center of Federal Medical & Biological Agency, Russia (1)  ·  National Cancer Institute (NCI) (1)  ·  National Jewish Health (1)  ·  Pearl Therapeutics, Inc. (1)  ·  Syntara (1)  ·  Teva Branded Pharmaceutical Products R&D, Inc. (1)  ·  The University of Texas Medical Branch, Galveston (1)  ·  United Therapeutics (1)  ·  University of Alabama at Birmingham (1)  ·  University of Chicago (1)

Countries

United States (9)  ·  Australia (1)  ·  France (1)  ·  Germany (1)  ·  Russia (1)

Top investigators

Adam Wanner, MD (1)  ·  Alexander V Averyanov, MD, PhD (1)  ·  Atul Malhotra, MD (1)  ·  Bijan Najafi, PhD (1)  ·  Charles Fogarty, MD (1)  ·  David Barnes, MBBS FRACP (1)  ·  George Bakris, MD (1)  ·  Mark Dransfield, MD (1)  ·  Randall J Urban, MD (1)  ·  Russell P Bowler, MD, PhD (1)  ·  Sharon McQuillan, MD (1)  ·  York E Miller (1)

NIH funding

P30CA060553 (1), P30DK072482 (1), UG1CA242643 (1)