8 completed, 5 recruiting, 4 terminated, 3 unknown. 24 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 24 | Completed 8, Recruiting 5, Terminated 4, Unknown 3, Withdrawn 3, Not yet recruiting 1 |
Follow Pressure Ulcer: new trials by email Literature Review of Pressure Ulcer trials Research Report on Pressure Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Study Title: A Multicenter, Prospective, Modified Platform Trial Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers. Activate™ Matrix + SOC, AmnioDefend™ FT Matrix + SOC, Palisade™ DM Matrix + SOC - Skin Ulcer, Pressure Ulcer (PU) | Phase 4 | Recruiting | Sequence LifeScience, Inc. | 2000 | 2026-01-28 | 2026-06-24 |
| Clinical Trial Evaluating a Single Layer Amniotic Membrane and Standard of Care in the Management of Nonhealing Pressure Ulcers Standard of Care, XPURT + SOC - Pressure Ulcer, Ulcer, Pressure | Phase 4 | Recruiting | Applied Biologics, LLC | 100 | 2025-06-11 | 2026-10-28 |
| Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers ACApatch™, caregraFT™, Standard of Care - Pressure Ulcer, Ulcer | Phase 4 | Recruiting | Tiger Biosciences, LLC. | 500 | 2025-05-20 | 2026-09-23 |
| Zinc Oxide VS MEBO MEBO Wound Ointment, zinc oxide - Pressure Injury, Pressure Injury Stage 2 | Phase 4 | Recruiting | King Abdullah Medical City | 76 | 2023-12-31 | 2025-09-26 |
| NPWTi on Closure of Chronic Pressure Sores V.A.C.Ulta™ Negative Pressure Wound Therapy System, Standard of Care (Wet-to-dry dressings) - Pressure Sore | Phase 4 | Recruiting | Northwestern University | 62 | 2022-09-26 | 2026-03-25 |
| Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound Fespixon Cream - Pressure Injury Stage 2 | Phase 4 | Terminated | Taipei Medical University WanFang Hospital | 10 | 2022-04-06 | 2024-05-01 |
| Use of a Hypercaloric and Hyperprotein Supplement Enriched with Immunonutrients in Multi-pathological Malnourished Patients to Improve the Incidence and Prevalence of Pressure Sores Atémpero, Control (Standard treatment) - Multimorbidity, Comorbidity | Phase 4 | Completed | University of Cadiz | 69 | 2022-01-01 | 2024-12-10 |
| Decreasing Intraoperative Skin Damage in Prone Position Surgeries Mepilex Border Flex® (MBF) dressing - Pressure Injury | Phase 4 | Completed | University of California, Los Angeles | 107 | 2021-07-02 | 2023-05-31 |
| Study on Pressure Ulcers Prevention With Mepilex® Border Sacrum Dressing in Scheduled Cardiovascular Surgery Mepilex® Border dressing, Standard care - Pressure Ulcers, Prevention | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 478 | 2018-12-10 | 2019-01-31 |
| Bioequivalence Study of Crushed Sofosbuvir/Velpatasvir Compared to the Whole Tablet sofosbuvir/velpatasvir tablet, sofosbuvir/velpatasvir crushed - HCV | Phase 4 | Withdrawn | Radboud University Medical Center | 2018-04-01 | 2020-12-07 | |
| Leptospermum Scoparium Honey and Wound Care for Pressure Ulcers Leptospermum scoparium honey, Standard of Care Treatment - Pressure Ulcers | Phase 4 | Withdrawn | New York City Health and Hospitals Corporation | 2018-03-01 | 2018-04-18 | |
| Study of SANTYL® vs Hydrogel (SoloSite®) for Pressure Ulcers Santyl, SoloSite® - Pressure Ulcer | Phase 4 | Terminated | Smith & Nephew, Inc. | 3 | 2016-08-01 | 2020-03-10 |
| Use of Santyl Within an Accountable Care Organization Santyl, Standard Care - Pressure Ulcer, Foot Ulcer, Diabetic | Phase 4 | Withdrawn | Smith & Nephew, Inc. | 2016-08-01 | 2017-03-15 | |
| Ketamine and Refractory Painful Care in a Palliative Unit Ketamine - Intractable Pain, Intensive Care | Phase 4 | Terminated | Lille Catholic University | 8 | 2016-05-01 | 2020-03-03 |
| Wound Management for Sacral Pressure Ulcers With Necrotic Tissue TheraHoney HD, SkinTegrity - Pressure Ulcers | Phase 4 | Completed | Medline Industries | 21 | 2014-12-01 | 2019-07-24 |
| Pressure Ulcer Healing With Microcyn Microcyn, Sterile saline - Pressure Ulcer, Spinal Cord Injuries | Phase 4 | Completed | University of Alabama at Birmingham | 65 | 2013-03-01 | 2018-11-06 |
| Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers. Quantum Negative Pressure Wound Therapy Device - Pressure Ulcers | Phase 4 | Unknown | Innovative Therapies, Inc. | 90 | 2012-12-01 | 2012-11-28 |
| Effect of Prolonged Decubitus on Nitric Oxide Concentration in Chronic Obstructive Pulmonary Disease Cardioline Exp'air by Medi-soft - Sorinnes (B) - Chronic Obstructive Airway Disease | Phase 4 | Completed | University of Milan | 30 | 2012-03-01 | 2014-10-29 |
| Prevention of Pressure Ulcers in Patients Under Non-Invasive Mechanical Ventilation Allevyn Thin®, Askina Transorbent Border®, Linovera® - Respiratory Failure | Phase 4 | Completed | B. Braun Medical SA | 152 | 2012-02-01 | 2015-08-18 |
Showing 20 of 24. Sign in to see all of them.
Skin Ulcer (4) · Ulcer (3) · Diabetic Foot (2) · Wounds and Injuries (2) · Agnosia (1) · Calciphylaxis (1) · Colitis, Ulcerative (1) · Craniocerebral Trauma (1) · Crohn Disease (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Diabetes Mellitus, Type 2 (1) · Enterocolitis, Pseudomembranous (1) · Epidermolysis Bullosa (1)
Skin Diseases (24) · Skin and Connective Tissue Diseases (24) · Skin Ulcer (20) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (6) · Cardiovascular Diseases (3) · Nervous System Diseases (3) · Nutritional and Metabolic Diseases (3) · Vascular Diseases (3) · Autoimmune Diseases (2) · Diabetes Complications (2) · Diabetic Angiopathies (2) · Diabetic Neuropathies (2) · Endocrine System Diseases (2) · Foot Ulcer (2)
Standard of Care (5) · Collagenases (2) · Bandages (1) · Bandages, Hydrocolloid (1) · Ketamine (1) · Negative-Pressure Wound Therapy (1) · Oxygen (1) · Preservatives, Pharmaceutical (1) · Sofosbuvir (1) · Zinc Oxide (1) · sofosbuvir-velpatasvir drug combination (1)
Smith & Nephew, Inc. (3) · Andaluz Health Service (1) · Applied Biologics, LLC (1) · B. Braun Medical SA (1) · Innovative Therapies, Inc. (1) · Jay C. Buckey Jr. (1) · King Abdullah Medical City (1) · Lille Catholic University (1) · Medline Industries (1) · Molnlycke Health Care AB (1) · New York City Health and Hospitals Corporation (1) · Northwestern University (1) · Radboud University Medical Center (1) · Sequence LifeScience, Inc. (1) · St. Joseph's Healthcare Hamilton (1)
United States (12) · Spain (3) · France (2) · Canada (1) · Germany (1) · Italy (1) · Netherlands (1) · Saudi Arabia (1) · Taiwan (1) · United Kingdom (1)
Jaime E Dickerson, PhD (2) · Thomas Serena, MD (2) · Carol Dealey, BSc (1) · Dr. Ebtisam AbdElatif Ebrahim, Master degree of science in nu (1) · Francisco Javier Navarro-Moya, Enfermero (1) · Gary Sibbald, MD (1) · Herbert B Slade, MD (1) · Hsian-Jenn Wang (1) · James Mahoney, MD (1) · Jay Buckey (1) · Joanne Greco, BScN (1)
PMID 24152576, PMID 25886152, PMID 28922519, PMID 32156618, PMID 39037095, PMID 42525684