18 completed, 2 not yet recruiting, 2 recruiting, 1 active not recruiting. 17 Not applicable, 4 Phase 4, 3 Phase 2, 2 Phase 3.
Follow Zinc Oxide: new trials by email Literature Review of Zinc Oxide trials Research Report on Zinc Oxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Salvadora Persica-Zinc Oxide Versus MTA as Pulpotomy Agents in Mature Permanent Molars With Irreversible Pulpitis Mineral Trioxide Aggregate, Salvadora persica Extract + Zinc Oxide - Irreversible Pulpitis | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 78 | 2026-06-20 | 2026-06-05 |
| Effect of Graphene Oxide on Vital and Non-Vital Primary Teeth Compared to the Conventional Techniques Graphene Oxide using vital pulpotomy technique, MTA using vital pulpotomy technique, Zinc Oxide and Eugenol using vital pulpotomy technique - Primary Teeth Indicated for Pulp Therapy | Not applicable | Not yet recruiting | Al-Azhar University | 126 | 2026-04-01 | 2026-02-20 |
| Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis zinc oxide, Placabo - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Faculty of Dental Medicine for Girls | 100 | 2025-06-30 | 2026-05-04 |
| Clinical and Radiographic Outcomes of Lesion Sterilization and Tissue Repair Using Zinc Oxide/ 6-gingerol Mix Versus Triple Antibiotic Paste in Non-vital Primary Molars Zinc oxide/ 6-gingerol mix, Triple antibiotic paste - Clinical Outcomes, Radiographic Outcomes | Not applicable | Recruiting | Al-Azhar University | 60 | 2024-10-01 | 2026-03-23 |
| Zinc Oxide VS MEBO MEBO Wound Ointment, zinc oxide - Pressure Injury, Pressure Injury Stage 2 | Phase 4 | Recruiting | King Abdullah Medical City | 76 | 2023-12-31 | 2025-09-26 |
| Assessment of the Rate of Oseointegration Surrounding Nano-coated Orthodontic Titanium Miniscrew Blank group, Silver hydroxyapatite, Zinc oxide - Health Care Utilization, Diet, Healthy | Not applicable | Completed | Al-Azhar University | 18 | 2023-01-01 | 2024-09-03 |
| Lesion Sterilization And Tissue Repair Versus Zinc Oxide And Eugenol For Treatment of Necrotic Primary Molars Lesion sterilization and tissue repair, zinc oxide and eugenol pulpectomy - Necrotic Primary Molars | Phase 2 / Phase 3 | Completed | Cairo University | 60 | 2022-10-01 | 2025-08-03 |
| Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) ALAC, inulin, FOS, and sodium butyrate, Sodium butyrate and zinc oxide - Rett Syndrome, Dysbiosis | Not applicable | Completed | Azienda Ospedaliera Universitaria Senese | 28 | 2022-04-01 | 2023-04-18 |
| Clinical Trial of Anusol Ointment for Symptom Relief in Patients With Haemorrhoids Anusol, Relief [Name], Placebo - Hemorrhoids | Phase 3 | Completed | Church & Dwight Company, Inc. | 66 | 2021-11-25 | 2022-08-15 |
| Non-instrumentation Root Canal Treatment of Primary Molars Non-instrumentation technique with use of CTZ paste, Instrumentation technique and filling with Zinc Oxide and Eugenol paste - Dental Pulp Diseases, Dental Pulp Necrosis | Not applicable | Completed | University of Sao Paulo | 180 | 2021-10-04 | 2025-07-03 |
| The Effect of Donepezil on Wound Healing Donepezil, Placebo oral tablet, Topical Zinc Oxide - Wound Heal | Phase 2 | Unknown | University of Maryland, Baltimore | 20 | 2020-08-30 | 2023-05-22 |
| Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy KeraStat Cream, Routine Skin Care - Commercially Available Agents - Head and Neck Cancer, Radiation Dermatitis | Not applicable | Completed | Wake Forest University Health Sciences | 28 | 2020-07-27 | 2025-03-17 |
| The Healthy Baby Bottoms Study Diaper care with Theraworx - Diaper Dermatitis | Phase 4 | Terminated | Linda Fu | 5 | 2020-03-12 | 2021-12-17 |
| Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light Zinc Oxide and Avobenzone - Sun Damaged Skin | Not applicable | Completed | University of California, Davis | 17 | 2017-03-17 | 2025-04-27 |
| Comparison of Barrier Products in the Prevention of Incontinence-associated Dermatitis in Hospitalized Elderly water and soap, zinc oxide, Non-Irritant Barrier Film - Diaper Rash | Not applicable | Completed | Federal University of Minas Gerais | 138 | 2016-05-01 | 2018-08-02 |
| Comparison of Iron Absorption From Extruded FePP-fortified Rice Containing Zinc, Citric Acid/Trisodium Citrate and EDTA Ferric Pyrophosphate and Zinc Oxide, Ferric Pyrophosphate and Zinc Sulphate, Ferric Pyrophosphate, ZnO, Citric Acid and Trisodium Citrate - Iron Deficiency and/or Anemia | Not applicable | Completed | Swiss Federal Institute of Technology | 30 | 2016-04-01 | 2016-12-07 |
| Pulpotomy Versus Pulpectomy in Vital Primary Incisors pulpotomy technique with formocresol, pulpectomy technique with zinc oxide and eugenol - Dental Caries, Pulp Disease, Dental | Not applicable | Completed | National Research Centre, Egypt | 39 | 2015-08-01 | 2022-10-21 |
| The Effect of Zinc on Iron Bioavailability From Fortified Extruded Rice Fortified With Ferric Pyrophosphate Ferric Pyrophosphate and Zinc Oxide, Ferrous sulfate, Ferric Pyrophosphate and Zinc Sulfate - Iron Deficiency | Not applicable | Completed | Swiss Federal Institute of Technology | 20 | 2015-04-01 | 2016-04-14 |
| Clinical Trial to Determine the Bioavailability of Three Different Zinc Preparations zinc-enriched yeast, Zinc references - Zinc Deficiency | Not applicable | Completed | Lesaffre International | 25 | 2014-10-01 | 2018-06-12 |
| Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma 290-400 nm sunscreen, 290-800 nm sunscreen - Melasma | Phase 4 | Completed | Universidad Autonoma de San Luis Potosà | 68 | 2012-09-01 | 2014-12-02 |
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Dental Pulp Diseases (2) · Diaper Rash (2) · Head and Neck Neoplasms (2) · Anemia, Iron-Deficiency (1) · Anxiety Disorders (1) · Behavior (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Dental Caries (1) · Dental Pulp Necrosis (1) · Depression (1) · Dysbiosis (1) · Epilepsy (1) · Esophageal Neoplasms (1)
Al-Azhar University (3) · Swiss Federal Institute of Technology (2) · Wake Forest University Health Sciences (2) · Azienda Ospedaliera Universitaria Senese (1) · Cairo University (1) · Church & Dwight Company, Inc. (1) · Emory University (1) · Faculty of Dental Medicine for Girls (1) · Federal University of Minas Gerais (1) · Johns Hopkins Bloomberg School of Public Health (1) · Jordan University of Science and Technology (1) · King Abdullah Medical City (1) · Lesaffre International (1) · Linda Fu (1) · National Research Centre, Egypt (1)
United States (6) · Egypt (4) · Switzerland (3) · Brazil (2) · Armenia (1) · Ghana (1) · Guatemala (1) · Italy (1) · Jordan (1) · Mexico (1) · Pakistan (1) · Saudi Arabia (1)
Annahita Ghassemi, PhD (1) · Aryeh D Stein, PhD (1) · Bertha Torres-Alvarez, MD (1) · Claudio De Felice, MD (1) · Diana Hernandez-Blanco, MD (1) · Dr. Ebtisam AbdElatif Ebrahim, Master degree of science in nu (1) · Fausto M Mendes, PhD (1) · Flavia F Ercole, Phd (1) · Gary G. Schwartz, MD, PhD, MPH (1) · Juan P Castanedo-Cazares, MD (1) · Lamia Gadallah, Researcher (1) · Michael B Zimmermann, Prof. Dr. (1) · Michael Zimmermann, Prof.Dr., MD (1) · Naglaa M. El-Wakeel, PhD (1)
PMID 14747673, PMID 16169549, PMID 16291354, PMID 16510631, PMID 16920858, PMID 17805430, PMID 18316268, PMID 20881069, PMID 21439564, PMID 22354676, PMID 23110976, PMID 24259556, PMID 28148685, PMID 28343659, PMID 38504243
P30CA012197 (1), R01MH067981 (1)