187 completed, 45 unknown, 19 recruiting, 13 active not recruiting. 188 Not applicable, 22 Phase 2, 13 Phase 4, 10 Phase 3, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-exercise Blood Pressure With Inorganic Nitrate Beetroot Juice - Active + Exercise, Beetroot juice placebo + Exercise, Beetroot Juice - Active + No exercise - Obese Individuals, Central Adiposity | Not applicable | Not yet recruiting | University of Virginia | 12 | 2026-10-15 | 2026-10-09 |
| How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver Imaging PET/MRI, Stable isotope infusions, meal test - Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Steato-Hepatitis (NASH) | Not applicable | Not yet recruiting | Université de Sherbrooke | 32 | 2026-09-01 | 2025-08-21 |
| Acupoint Catgut Embedding With Laser Acupuncture for Weight Loss in Adults With Obesity Acupoint catgut embedding, Active laser acupuncture, Sham laser acupuncture - Obesity, Obesity, Abdominal | Not applicable | Not yet recruiting | Taipei City Hospital | 120 | 2026-09-01 | 2026-08-18 |
| A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity Orforglipron, Placebo - Overweight, Prediabetic State | Phase 3 | Recruiting | Eli Lilly and Company | 2001 | 2026-08-26 | 2026-10-08 |
| Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults Polygonatum sibiricum, Lifestyle Intervention - Visceral Obesity, Metabolic Syndrome | Not applicable | Not yet recruiting | Zhejiang Provincial Tongde Hospital | 66 | 2026-08-15 | 2026-08-12 |
| Body Roundness Index and Mortality in ICU Patients Critical Illness, Obesity & Overweight | Not yet recruiting | Ondokuz Mayıs University | 550 | 2026-08-01 | 2026-06-08 | |
| Effect of Thoracic Mobilization in People With Central Obesity Mulligan Thoracic Mobilization, low carbohydrate, Aerobic Exercise - Central Obesity, Ventilatory Function | Not applicable | Active not recruiting | Cairo University | 60 | 2026-07-25 | 2026-10-05 |
| CPAP in Patients With Severe Obesity After Anesthesia Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure - Obesity, Abdominal, Anesthesia Morbidity | Not applicable | Not yet recruiting | Massachusetts General Hospital | 60 | 2026-06-01 | 2025-11-18 |
| Metabolic Effectiveness of Extracorporeal Shockwave on Abdominal Adiposity conventional balanced, low-calorie diet 1500 k/cal for 12 weeks, aerobic training program, extracorporeal shockwave therapy - Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome | Not applicable | Enrolling by invitation | Cairo University | 90 | 2026-06-01 | 2026-07-07 |
| Peer-modeled Intervention A peer-modelled behavioural change intervention - Cardio-metabolic Health | Not applicable | Active not recruiting | KU Leuven | 157 | 2026-05-04 | 2026-10-23 |
| Epicardial Fat Tissue and Cardiometabolic Risk in Russian and Asian Populations Epicardial Fat Tissue (EFT), Chronic Non-Communicable Diseases (NCDs) | Recruiting | National Medical Research Center for Therapy and Preventive Medicine | 500 | 2026-05-04 | 2026-05-22 | |
| Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure Transcutaneous Electrical Nerve Stimulation, Isometric Exercise, Aerobic, Dynamic Resistance, stretch and Breathing Exercises and Lifestyle Modification Advices - Resistant Hypertension, Hemodynamic Instability | Not applicable | Recruiting | Mohamed Mohamed Ali Morgan | 50 | 2026-01-15 | 2026-02-03 |
| Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects The Nitraria retusa arm - Treatment Resistant Schizophrenia, Obesity & Overweight | Not applicable | Recruiting | Faculty of Medicine, Sousse | 30 | 2026-01-03 | 2026-09-14 |
| Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity whole body vibration training, control group - Dynapenia, Abdominal Obesity | Not applicable | Not yet recruiting | Dalin Tzu Chi General Hospital | 120 | 2025-10-01 | 2025-09-18 |
| Long-Term Effects of Walnut Consumption on Brain Function Walnuts - Healthy, Brain Insulin Sensitivity | Not applicable | Recruiting | Maastricht University Medical Center | 55 | 2025-10-01 | 2026-07-24 |
| Suture Length Effects in Acupoint Implantation for Abdominal Obesity 1 inch, 0.5 inch - Abdominal Obesity, Obesity | Not applicable | Active not recruiting | Chang Gung Memorial Hospital | 78 | 2025-08-01 | 2025-08-15 |
| Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity Chronotype-matched time-restricted eating, Chronotype-unmatched time-restricted eating - Central Obesity, Time Restricted Eating | Not applicable | Enrolling by invitation | Chinese University of Hong Kong | 90 | 2025-07-31 | 2026-08-31 |
| Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV Tesamorelin, Placebo, Exercise - HIV-1-infection, Frailty | Phase 2 | Recruiting | Massachusetts General Hospital | 100 | 2025-07-10 | 2026-05-19 |
| Evaluation of Exercise Capacity in Teenage Females Using Virtual Reality and Plyometric Workout virtual reality and plyometric workout - Abdominal Obesity | Not applicable | Recruiting | New Ismailia National University | 100 | 2025-06-20 | 2025-12-03 |
| Cistanche Deserticola Extract Combined With Aerobic Exercise Improves Body Composition, Insulin Resistance and Inflammation in Men With Central Obesity Supervised Aerobic Exercise, Cistanche deserticola Extract - Central Obesity, Insulin Resistance | Not applicable | Completed | Beijing Sport University | 125 | 2025-06-01 | 2026-03-20 |
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Obesity (112) · Metabolic Syndrome (59) · Insulin Resistance (49) · Hypertension (38) · Diabetes Mellitus, Type 2 (25) · Motor Activity (25) · Overweight (23) · Weight Loss (22) · Diabetes Mellitus (17) · Dyslipidemias (16) · Glucose Intolerance (13) · Cardiovascular Diseases (11) · Fatty Liver (10) · Hypertriglyceridemia (10)
Nutritional and Metabolic Diseases (289) · Overnutrition (289) · Pathological Conditions, Signs and Symptoms (289) · Signs and Symptoms (289) · Nutrition Disorders (288) · Body Weight (281) · Overweight (266) · Obesity (177) · Metabolic Diseases (126) · Glucose Metabolism Disorders (115) · Hyperinsulinism (90) · Endocrine System Diseases (48) · Cardiovascular Diseases (47) · Vascular Diseases (44) · Insulin Resistance (41)
Exercise (19) · Caloric Restriction (9) · Nutrition Assessment (5) · Acupuncture Therapy (4) · Diet (4) · Hydrochlorothiazide (4) · Metformin (4) · Resistance Training (4) · tesamorelin (4) · 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid (3) · Amlodipine (3) · Blood Specimen Collection (3) · Liraglutide (3) · Walking (3) · candesartan (3)
Cairo University (11) · Massachusetts General Hospital (7) · University of Guadalajara (7) · Laval University (6) · Mayo Clinic (5) · Bogomolets National Medical University (4) · The University of Hong Kong (4) · University of Southern California (4) · Escola Superior de Tecnologia da Saúde do Porto (3) · Genfit (3) · Hospices Civils de Lyon (3) · Hubei Hospital of Traditional Chinese Medicine (3) · Maastricht University Medical Center (3) · Universidade Federal do Rio de Janeiro (3) · University of Aarhus (3)
United States (57) · Canada (20) · China (18) · Egypt (16) · France (15) · Turkey (Türkiye) (10) · Sweden (9) · Denmark (8) · Germany (8) · Mexico (8) · Spain (8) · Brazil (7) · Hong Kong (7) · Italy (6) · Finland (5)
Nazarii Kobyliak, PhD (3) · Andreia Noites, MSc (2) · Haibo Zhang, MD (2) · Jing Li, PhD (2) · John Sievenpiper, MD,PhD,FRCPC (2) · Josiemer Mattei, PhD, MPH (2) · Ming Fai Parco Siu, PhD (2) · Parco M. Siu, PhD (2) · Philippe Pibarot, PhD, DVM (2) · Robert Ross (2) · SoJung Lee, PhD (2) · Sonia Anand, MD, PhD (2)
PMID 23703580, PMID 21816979, PMID 31235380, PMID 32674604, PMID 33512717, PMID 33739874, PMID 10480510, PMID 10868854, PMID 10963727, PMID 11411567, PMID 11556815, PMID 11576521, PMID 12101852, PMID 12523673, PMID 12622244, PMID 13211501, PMID 15168555, PMID 15333514, PMID 15562250, PMID 16054141, PMID 16446745, PMID 16608613, PMID 16626303, PMID 1695875, PMID 16959033, PMID 17069794, PMID 17086191, PMID 17112576, PMID 17116424, PMID 17217636, PMID 17329046, PMID 17578889, PMID 17805543, PMID 17893688, PMID 18191057, PMID 18266981, PMID 19010618, PMID 19100718, PMID 19171808, PMID 19211823, PMID 19587363, PMID 19680673, PMID 19691178, PMID 19819963, PMID 19935427, PMID 20212264, PMID 20463039, PMID 20812281, PMID 21261640, PMID 21385509
P30CA014089 (2), 2008 (1), 2009 (1), 2018 (1), 2023 (1), K01DK140206 (1), K23DK106520 (1), K23HL086558 (1), R01AG020583 (1), R01DK045343 (1), R01DK132870 (1), R01HL077674 (1), R01HL085268 (1), R01HL092280 (1), R21AG060139 (1)