18 completed, 4 unknown, 3 not yet recruiting, 2 recruiting. 25 Not applicable, 3 Phase 1, 2 Phase 2, 2 Phase 3, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| C2001P-CS3: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIV HPV DNA Testing (Abbott Alinity m HPV Assay), Visual Inspection with Acetic Acid, Cervical Histology (Biopsy Procedures) - Human Papillomavirus (HPV), HPV Associated Cancers | Not applicable | Not yet recruiting | University of California, San Diego | 750 | 2026-11-30 | 2026-10-29 |
| Acetic Acid Ear Drops Versus 0.3 % Ciprofloxacin for Chronic Suppurative Otitis Media. Acetic Acid 2% Ear Drops, Ciprofloxacin 0.3% Otic Solution - Otitis Media Chronic | Not applicable | Not yet recruiting | Dow University of Health Sciences | 146 | 2026-09-23 | 2026-09-22 |
| The Mother-Daughter Project: Merck-4 Gardisil-9, High Risk HPV DNA Testing, Visual Inspection with acetic acid (VIA) and possible cervical biopsy - Cervical Dysplasia | Not applicable | Not yet recruiting | Indiana University | 2500 | 2026-02-01 | 2026-01-15 |
| Acetic Acid 2% Solution for Skin Ulcers Acetic Acid, Prontosan - Ulcer, Skin | Phase 3 | Recruiting | Consorci Sanitari de l'Alt Penedès i Garraf | 104 | 2025-04-27 | 2026-10-27 |
| Validation of a Lab-free Low-cost Screening Test for Prevention of Cervical Cancer HPV Test, EVA System, Visual Inspection with Acetic Acid (VIA) - Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia | Not applicable | Recruiting | DL Analytics | 10000 | 2025-02-12 | 2026-01-29 |
| Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial 85%TCA topical application, 3% acetic acid - Cervical Intraepithelial Neoplasia, Trichloroacetic Acid | Phase 2 | Unknown | Department of Medical Services Ministry of Public Health of Thailand | 44 | 2024-08-01 | 2024-11-14 |
| Resistance Exercise Plus Vinegar Ingestion on Biomarkers in Healthy Adults Vinegar liquid, vinegar pill - LPS, Mood Disorders | Not applicable | Completed | Arizona State University | 29 | 2024-05-22 | 2025-04-09 |
| A Cervical Cancer Prevention Program in Kenya High Risk HPV DNA Testing, Visual Inspection with acetic acid (VIA) and possible cervical biopsy, Gardisil-9 - Cervical Cancer Prevention, Cervical Cancer | Not applicable | Active not recruiting | Indiana University | 2300 | 2024-04-02 | 2026-01-16 |
| Daily Vinegar Ingestion and 24-Hour Blood Glucose Control Liquid vinegar, vinegar pill - Glucose Intolerance | Not applicable | Completed | Arizona State University | 10 | 2024-03-26 | 2025-08-17 |
| Efficacy of Topical 95% TCA in the Treatment of CIN 1 or Less After Low-grade Abnormality of Screening Test Trichloroacetic acid - CIN1, Trichloroacetic Acid | Phase 2 / Phase 3 | Withdrawn | Department of Medical Services Ministry of Public Health of Thailand | 2023-11-30 | 2024-01-03 | |
| Daily Vinegar Ingestion and Metabolic Health Liquid vinegar, Vinegar pill - Inflammation, Metabolic Syndrome | Not applicable | Completed | Arizona State University | 36 | 2023-02-01 | 2024-01-31 |
| Vinegar-induced Collection of Duodenal Pancreatic Juice Via Endoscopic Ultrasound Vinegar 20ml, Saline (NaCl 0,9 %) (placebo), Vinegar 40ml - Pancreatic Cancer | Not applicable | Completed | Peking Union Medical College Hospital | 75 | 2022-12-30 | 2026-04-02 |
| Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction Vaginal washing with 5% acetic acid, Vaginal washing with 0.9% NS - Labor, Induced, Induced; Birth | Not applicable | Completed | Alexandra Hospital, Athens, Greece | 230 | 2021-10-29 | 2024-02-20 |
| Effect of Daily Vinegar Ingestion for Four Weeks on Mood State in Healthy College Students apple cider vinegar, vinegar pill - Mood, Depression | Not applicable | Completed | Arizona State University | 25 | 2020-09-29 | 2021-01-13 |
| Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer Alpha-tocopheryloxyacetic Acid, Trastuzumab - Anatomic Stage IV Breast Cancer AJCC v8, HER2 Positive Breast Carcinoma | Phase 1 | Suspended | Veana Therapeutics | 24 | 2020-04-08 | 2024-07-10 |
| Evaluating the Effect of Bathing Additives in Atopic Dermatitis Dilute vinegar (acetic acid), Dilute bleach - Atopic Dermatitis, Eczema | Not applicable | Terminated | University of Arizona | 3 | 2019-07-01 | 2021-06-04 |
| Effect of Apple Cider Vinegar and Metformin Combination vs Metformin Alone in Type 2 Diabetics Metformin Oral Tablet, Vinegar - Diabetes Mellitus, Type 2 | Not applicable | Completed | Ziauddin University | 126 | 2019-04-22 | 2019-10-21 |
| The Role of Bathing Additives in the Treatment of Pediatric Atopic Dermatitis Water, Bleach, Acetic acid - Atopic Dermatitis, Eczema | Not applicable | Terminated | Mayo Clinic | 5 | 2019-02-21 | 2021-05-12 |
| Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10% Mizkan rice vinegar with acetic acid, Mizkan rice vinegar without acetic acid - Prehypertension | Not applicable | Unknown | Mizkan Holdings Co., Ltd. | 130 | 2018-09-11 | 2019-07-30 |
| The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration liquid vinegar, vinegar pill - Visceral Obesity, Tooth Erosion | Not applicable | Completed | Carol Johnston | 102 | 2017-01-05 | 2019-08-28 |
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Uterine Cervical Neoplasms (7) · Uterine Cervical Dysplasia (6) · Depression (3) · Diabetes Mellitus, Type 2 (3) · Dermatitis, Atopic (2) · Eczema (2) · Acquired Immunodeficiency Syndrome (1) · Barrett Esophagus (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Erythema (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1) · Genital Neoplasms, Female (1)
Arizona State University (4) · Department of Medical Services Ministry of Public Health of Thailand (2) · Indiana University (2) · M.D. Anderson Cancer Center (2) · Alexandra Hospital, Athens, Greece (1) · Attikon Hospital (1) · Carol Johnston (1) · Changhai Hospital (1) · Consorci Sanitari de l'Alt Penedès i Garraf (1) · DL Analytics (1) · Dow University of Health Sciences (1) · HealthPartners Institute (1) · Istituto Clinico Humanitas (1) · Maastricht University Medical Center (1) · Mayo Clinic (1)
United States (11) · China (3) · Kenya (3) · Pakistan (2) · Thailand (2) · Botswana (1) · Brazil (1) · Canada (1) · El Salvador (1) · Greece (1) · Italy (1) · Netherlands (1) · Spain (1) · United Kingdom (1)
Kathleen Schmeler, MD (2) · Alessandro Repici, MD (1) · Carol S Johnston, PhD (1) · Cesare Hassan, MD (1) · David Levitz, PhD (1) · Dr Momina Abid, MBBS,M Phil (ongoing) (1) · Dr Zahida Memon, MBBS,M Phil,PhD (1) · George D Dimitriadis, Professor (1) · Georgios Daskalakis (1) · Gina Ogilvie, MD FCFP DrPH (1) · Karla Alfaro, MD (1) · Lydia Bazzano, MD, PhD (1) · Marta De Vicente (1) · Matthieu P DeClerck, MD (1) · Megha M Tollefson, MD (1)
PMID 25849627, PMID 26064976, PMID 29633339, PMID 33297831
R01CA186132 (1), R44CA247137 (1), U24CA275417 (1), UG1CA275414 (1), UG1CA275416 (1)