3 completed, 3 recruiting, 1 active not recruiting, 1 enrolling by invitation. 5 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Recruiting 2, Active not recruiting 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Post-traumatic Stress: new trials by email Literature Review of Post-traumatic Stress trials Research Report on Post-traumatic Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation - Anxiety, PTSD | Not applicable | Active not recruiting | Tactical Mind Research Coalition, Inc. | 240 | 2026-08-01 | 2026-09-16 |
| A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses Surveys - Moral Injury, Moral Distress | Enrolling by invitation | Mayo Clinic | 21300 | 2026-03-03 | 2026-09-17 | |
| Behavioral Health Collaborative Care Model in an ICU Recovery Clinic Behavioral Health Collaborative Care Model - PICS, Anxiety | Not applicable | Recruiting | Medical University of South Carolina | 150 | 2026-01-30 | 2026-03-12 |
| Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) Cyclobenzaprine HCl, Placebo - Acute Stress Reaction, Acute Stress Disorder | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 180 | 2025-03-25 | 2026-10-22 |
| CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I) - Traumatic Brain Injury, Insomnia | Not applicable | Recruiting | Johns Hopkins University | 360 | 2024-05-10 | 2026-07-13 |
| IVF Failure and Pregnancy Loss on Couples' Psychological Stress Fertilization in Vitro, Pregnancy Loss | Unknown | The First Hospital of Jilin University | 150 | 2024-05-01 | 2024-04-26 | |
| Post-traumatic Stress Disorder After Pediatric Intensive Care Unit Hospitalization Post traumatic stress disorder questionnaire - Post-traumatic Stress | Not applicable | Completed | University Hospital, Toulouse | 87 | 2021-01-26 | 2022-11-15 |
| Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress Cervical Transcutaneous Vagus Nerve Stimulation (Active Comparator), Cervical Transcutaneous Vagus Nerve Stimulation (Sham Comparator) - Post-traumatic Stress | Phase 1 / Phase 2 | Completed | VA Office of Research and Development | 88 | 2019-02-04 | 2025-04-10 |
| Wellbeing and Stress Among Mobile Phone Dispatched Lay Responders Exposure: First on scene - Stress, Psychological, Post-traumatic Stress | Terminated | Karolinska Institutet | 460 | 2019-01-09 | 2020-10-19 | |
| Effectiveness of Pain Neuroscience Education (PNE) to Veterans With Post-Traumatic Stress and Low Back Pain Pain Neuroscience Education, Exercise, Traditional Education - Chronic Low Back Pain, Post-traumatic Stress | Not applicable | Completed | Keller Army Community Hospital | 47 | 2017-07-01 | 2021-10-27 |
Anxiety Disorders (3) · Depression (3) · Stress Disorders, Post-Traumatic (3) · Stress, Psychological (2) · Attention Deficit Disorder with Hyperactivity (1) · Brain Concussion (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Craniocerebral Trauma (1) · Critical Illness (1) · Inflammation (1) · Memory Disorders (1) · Parasomnias (1) · Psychological Well-Being (1) · Sleep Initiation and Maintenance Disorders (1)
Mental Disorders (6) · Behavior (5) · Behavioral Symptoms (4) · Stress Disorders, Traumatic (4) · Trauma and Stressor Related Disorders (4) · Pathological Conditions, Signs and Symptoms (3) · Nervous System Diseases (2) · Pathologic Processes (2) · Sleep Wake Disorders (2) · Attention Deficit and Disruptive Behavior Disorders (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Chemically-Induced Disorders (1) · Disease Attributes (1) · Dyssomnias (1)
Cognitive Behavioral Therapy (1) · Exercise (1) · Eye Movement Desensitization Reprocessing (1) · Sugars (1) · Surveys and Questionnaires (1) · Transcranial Direct Current Stimulation (1) · cyclobenzaprine (1)
Johns Hopkins University (1) · Karolinska Institutet (1) · Keller Army Community Hospital (1) · Mayo Clinic (1) · Medical University of South Carolina (1) · Tactical Mind Research Coalition, Inc. (1) · The First Hospital of Jilin University (1) · University Hospital, Toulouse (1) · University of North Carolina, Chapel Hill (1) · VA Office of Research and Development (1)
United States (7) · China (1) · France (1) · Sweden (1)
Brian Pinkston, MD, MPH (1) · Cheryl Lowry, MD, MPH (1) · Christopher Jones, MD (1) · Cindy Tofthagen, PhD (1) · Imanuel R Lerman, MD MSc (1) · Luis Buenaver, PhD (1) · Mattias Ringh, MD PhD (1) · Melissa A Wilson, PhD (1) · Qi Xi, doctorate (1) · Rita Bakhru, MD (1) · Samuel McLean, MD (1)
PMID 17655731, PMID 18086173, PMID 18484439, PMID 20443659, PMID 25928197, PMID 2863605, PMID 29117321, PMID 29555319, PMID 33032364, PMID 33313697, PMID 36873081, PMID 37332387, PMID 9022608, PMID 9830973