11 unknown, 9 completed, 4 recruiting, 2 withdrawn. 2 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 2 |
| Not applicable | 1 | Unknown 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 2 | 1 | Terminated 1 |
Follow pediatric multisystem inflammatory disease, COVID-19 related: new trials by email Literature Review of pediatric multisystem inflammatory disease, COVID-19 related trials Research Report on pediatric multisystem inflammatory disease, COVID-19 related
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiovascular Assessment 5 Years After MIS-C Multisystem Inflammatory Syndrome in Children (MIS-C), SARS-CoV-2 Infection | Recruiting | Medical University of Warsaw | 90 | 2025-11-22 | 2026-06-22 | |
| Quality of Life in Children After Multisystem Inflammatory Syndrome in Children Multisystem Inflammatory Syndrome in Children (MIS-C) | Completed | Kristina Lah Tomulić | 85 | 2024-04-01 | 2026-10-21 | |
| Multiparametric Echocardiography and Cardiac Biomarkers in Pediatric Inflammatory Heart Diseases study of biological samples and echocardiographic data and link with need of hemodynamic support - Myocarditis, Pediatric Inflammatory Multisystem Syndrome | Unknown | Central Hospital, Nancy, France | 100 | 2023-09-01 | 2023-08-30 | |
| Investigation of Prognostic Biomarkers, Host Factors and Viral Factors for COVID-19 in Children delineate its prognostic biomarker, host genetic factors, immunopathogenesis and viral pathogenesis - COVID-19-Associated Encephalitis, Multisystem Inflammatory Syndrome in Children | Unknown | National Taiwan University Hospital | 300 | 2022-08-01 | 2022-10-14 | |
| PIMS-TS in Intensive Care: Retrospective Cohort Trial PIMS-TS diagnostic a treatment - Pims-Ts | Completed | Brno University Hospital | 180 | 2022-08-01 | 2023-02-14 | |
| Clinical Characteristics and Long Term Impact on Pediatric COVID-19 in Taiwan sequelae tracking - Long Covid19, COVID-19 Pneumonia | Recruiting | National Taiwan University Hospital | 3000 | 2022-07-01 | 2023-11-18 | |
| Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition Saliva collection at home - COVID-19, Post-Acute COVID-19 | Unknown | Leiden University Medical Center | 400 | 2022-06-28 | 2023-02-10 | |
| Multisystem Inflammatory Syndrome In Children at Sohag University Hospital CBC, ESR ,CRP,Liver Function ,renal function ,ABG,Na,K,D-dimmer ,cardiac enzyme,ferritin ,blood and urine culture in negative cases - Multisystem Inflammatory Syndrome in Children | Unknown | Sohag University | 50 | 2022-06-01 | 2022-05-19 | |
| Genetic Basis of SARS-CoV-2 Infection-Associated Multisystem Inflammatory Syndrome in Children (MIS-C) MIS-C Associated With COVID-19 | Recruiting | Istituto Giannina Gaslini | 150 | 2022-02-23 | 2026-10-19 | |
| Study of Virus-specific Lymphocytic Cell Populations in Non-invasive Nasal Mucosa Samples of MIS-C Patients MIS-C Associated With COVID-19, COVID-19 | Unknown | Medical University of Warsaw | 20 | 2021-12-06 | 2022-09-30 | |
| Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C Cardiopulmonary exercise test (CPET), Peripheral Arterial Tonography (PAT) using the EndoPAT™ device, Endothelin - COVID-19, MIS-C Associated With COVID-19 | Not applicable | Unknown | Rambam Health Care Campus | 50 | 2021-11-01 | 2022-01-25 |
| Coronavirus-19 (COVID-19) and Related Outcomes in School Aged Children (ABC Health Outcomes in Children) Covid19; MIS-C | Withdrawn | Duke University | 2021-10-15 | 2021-09-16 | ||
| AT1001 for the Treatment of COVID-19 Related MIS-C Larazotide Acetate, Placebo - Covid19, Multisystem Inflammatory Syndrome in Children | Phase 2 | Terminated | Massachusetts General Hospital | 12 | 2021-10-01 | 2024-06-13 |
| Immun Response in Children With MIS-C Analysis of cytokines and immun cell related markers - MIS-C Multisystem Inflammatory Syndrome in Children | Unknown | University of Cologne | 20 | 2021-09-01 | 2021-09-22 | |
| Pediatric COVID Outcomes Study (PECOS) Covid19, MIS-C Associated With COVID-19 | Completed | Children's National Research Institute | 1097 | 2021-07-23 | 2026-10-08 | |
| Incidence of MIS-C and Other Complications Following SARS-CoV-2 Infection SARS CoV 2 Infection, Multisystem Inflammatory Disease, Pediatric, COVID-19 Related | Unknown | Copenhagen University Hospital, Rigshospitalet | 150 | 2021-07-15 | 2023-02-23 | |
| Paediatric Inflammatory Multisystem Syndrome During COVID-19 Pandemic Paediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-Cov-2 | Completed | Anglia Ruskin University | 40 | 2021-06-22 | 2022-02-09 | |
| Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland (SWISSPED-RECOVERY) Methylprednisolone sodium succinate 10 mg/kg intravenously, Human normal immunoglobulin (IVIg) - Paediatric Inflammatory Multisystem Syndrome-Temporally Associated With SARS-CoV-2 (PIMS-TS) | Phase 3 | Completed | University Children's Hospital Basel | 76 | 2021-05-23 | 2025-02-13 |
| Infusions of Mesenchymal Stromal Cells in Children With Multisystem Inflammatory Syndrome Human Cord Tissue Mesenchymal Stromal Cells (hCT-MSCs) - Multisystem Inflammatory Syndrome in Children | Phase 1 | Withdrawn | Joanne Kurtzberg, MD | 2021-03-12 | 2021-09-14 | |
| MISC COVID-19 Study in Pediatric Population SARS-CoV2 Infection, Multisystem Inflammatory Syndrome in Children | Unknown | Tuberculosis Research Centre, India | 180 | 2020-12-23 | 2024-05-30 |
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COVID-19 (20) · Post-Acute COVID-19 Syndrome (3) · Coronavirus Infections (2) · Mucocutaneous Lymph Node Syndrome (2) · Adrenal Insufficiency (1) · Arrhythmias, Cardiac (1) · Attention Deficit Disorder with Hyperactivity (1) · Bronchopulmonary Dysplasia (1) · Cellulitis (1) · Critical Illness (1) · Cytokine Release Syndrome (1) · Diabetes Mellitus (1) · Down Syndrome (1) · Edema (1)
Coronaviridae Infections (21) · Infections (21) · Nidovirales Infections (21) · RNA Virus Infections (21) · Virus Diseases (21) · Lung Diseases (20) · Pneumonia, Viral (20) · Respiratory Tract Diseases (20) · Respiratory Tract Infections (20) · Coronavirus Infections (19) · Pneumonia (19) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Disease Attributes (4) · Chronic Disease (3)
Hydrocortisone (2) · Abatacept (1) · Albuterol (1) · Aminocaproic Acid (1) · Amiodarone (1) · Aspirin (1) · Azithromycin (1) · Beclomethasone (1) · Blood Cell Count (1) · Bosentan (1) · Budesonide (1) · Bumetanide (1) · COVID-19 Serological Testing (1) · Cefdinir (1) · Cefepime (1)
Medical University of Warsaw (3) · Copenhagen University Hospital, Rigshospitalet (2) · Duke University (2) · National Taiwan University Hospital (2) · Anglia Ruskin University (1) · Brno University Hospital (1) · Carelon Research (1) · Central Hospital, Nancy, France (1) · Children's Hospital of Philadelphia (1) · Children's National Research Institute (1) · Istituto Giannina Gaslini (1) · Joanne Kurtzberg, MD (1) · Kristina Lah Tomulić (1) · Leiden University Medical Center (1) · Massachusetts General Hospital (1)
United States (7) · Poland (3) · Canada (2) · Denmark (2) · Taiwan (2) · United Kingdom (2) · Croatia (1) · Czechia (1) · Egypt (1) · Estonia (1) · France (1) · Germany (1) · India (1) · Israel (1) · Italy (1)
Luna-Yin Chang, professor (2) · Betty Diamond, MD (1) · Chi Hornik (1) · Emmeline P Buddingh, MD, PhD (1) · Gina A. Montealegre Sanchez, MD, MS (1) · Ignacio Sanz, MD (1) · James D. Wilkinson, MD, MPH (1) · Jeremy Boss, PhD (1) · Jo-Anne Johnson, MRCPCH, PhD (1) · Joanne Kurtzberg, MD (1) · Julia Bielicki, Dr. med. (1) · Kanecia Zimmerman, MD (1) · Kenneth M. Borow, MD (1) · Luregn Schlapbach, Dr. med. (1)
PMID 33172887, PMID 33579813, PMID 34473343, PMID 35081803, PMID 35526537, PMID 35669398, PMID 36030353, PMID 36322537, PMID 36634692, PMID 36746174, PMID 38107550, PMID 38670610, PMID 39695262, PMID 40181776, PMID 40737433, PMID 41850445, PMID 41990330, PMID 42070008, PMID 42347971