fludarabine phosphate: Clinical Trials

832 trials of fludarabine phosphate, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

423 completed, 150 terminated, 85 recruiting, 69 active not recruiting. 523 Phase 2, 354 Phase 1, 45 Phase 3, 39 Not applicable, 11 Early Phase 1.

By phase and status

PhaseTrialsStatus
Phase 2523Completed 284, Terminated 105, Recruiting 46, Active not recruiting 34, Unknown 24, Withdrawn 23, Not yet recruiting 6, Suspended 1
Phase 1354Completed 153, Recruiting 62, Terminated 52, Active not recruiting 40, Withdrawn 25, Unknown 14, Not yet recruiting 4, Suspended 4
Phase 345Completed 28, Terminated 7, Active not recruiting 3, Recruiting 2, Unknown 2, Withdrawn 2, Enrolling by invitation 1
Not applicable39Completed 20, Terminated 10, Unknown 4, Withdrawn 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1
Early Phase 111Completed 3, Terminated 3, Unknown 2, Withdrawn 2, Active not recruiting 1
Phase 47Completed 5, Unknown 2

Follow this drug Literature Review of fludarabine phosphate trials Research Report on fludarabine phosphate

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma
Allogeneic Hematopoietic Stem Cell Transplantation, Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10, Cyclophosphamide - Multiple Myeloma, Recurrent Multiple Myeloma
Phase 1WithdrawnFred Hutchinson Cancer Center2027-06-012026-09-11
CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome
Busulfan, Melphalan, Fludarabine - Myelodysplastic Syndromes, Graft Vs Host Disease
Not applicableNot yet recruitingGuenther Koehne622027-01-012026-10-13
CD34+ Transplants for Myeloid Malignancies
Busulfan, Melphalan, Fludarabine - Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute
Phase 2Not yet recruitingGuenther Koehne502027-01-012026-10-13
Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma
Fludarabine, Cyclophosphamide, CD70.CAR NK Cells - Large B-cell Lymphoma, Hodgkin Lymphoma
Phase 2Not yet recruitingM.D. Anderson Cancer Center1002026-12-282026-07-15
Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML
Fludarabine, Cytarabine, Idarubicin - Myeloid Leukemia
Phase 1 / Phase 2Not yet recruitingM.D. Anderson Cancer Center302026-11-302026-10-13
Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Acute Myeloid Leukemia With Complex Karyotype, Myelodysplastic Chronic Myelomonocytic Leukemia
Phase 2RecruitingCity of Hope Medical Center352026-11-052026-10-08
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
aldesleukin, cyclophosphamide, fludarabine phosphate - Malignancy, Hematologic, Neoplasms, Hematologic
Phase 1RecruitingNational Cancer Institute (NCI)862026-10-262026-10-21
Study of Zola-cel (BMS-986353), in Participants With Autoimmune Cytopenia (Breakfree-AiCE)
BMS-986353, Fludarabine Phosphate, Cyclophosphamide - Chronic Immune Thrombocytopenia, Autoimmune Hemolytic Anemia
Phase 2Not yet recruitingJuno Therapeutics, Inc., a Bristol-Myers Squibb Company522026-08-312026-07-09
B7-H3.CD28Z.CART in Solid Tumors
B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide - Pediatric Solid Tumor, Neuroblastoma
Phase 1RecruitingRobbie Majzner402026-08-242026-09-03
Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum
TGFBR2 KO CAR27/IL-15 NK cells, Rimiducid (AP1903), Fludarabine - Gastric Cancer, Metastatic
Phase 1 / Phase 2RecruitingM.D. Anderson Cancer Center102026-08-112026-10-08
Phase 1 Study Of LNK001 In Advanced Or Metastatic Clear Cell Renal Cell Carcinoma
Cyclophosphamide, Fludarabine, LNK001 - Clear Cell Renal Cell Carcinoma
Phase 1RecruitingM.D. Anderson Cancer Center402026-07-022026-10-09
Phase1 Basket Trial Of CAR.70-Engineered IL15-Transduced With TGFBR2 Knock Out Cord Blood-Derived NK Cells For Relapsed/Refractory Lymphoid Malignancies
Fludarabine, TGFBR2 KO CAR27/IL-15 NK cells, Cyclophosphamide - Lymphoid, Hodgkin Lymphoma
Phase 1RecruitingM.D. Anderson Cancer Center602026-05-282026-09-08
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Cord Blood Units, Total Body Irradiation, Cyclophosphamide - Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia
Phase 2RecruitingMemorial Sloan Kettering Cancer Center712026-04-282026-05-14
Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")
Cyclophosphamide, Fludarabine, Cetuximab - Colorectal Cancer, Peritoneal Metastases
Phase 1 / Phase 2RecruitingM.D. Anderson Cancer Center282026-04-202026-10-05
Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer
ETB-DualNK-01, Fludarabine, Cyclophosphamide - Metastatic Castration-resistant Prostate Cancer, Advanced Prostate Adenocarcinoma
Phase 1RecruitingBeijing Biotech362026-03-022026-06-11
Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma
EB-DTKN-401 allogeneic dual-target CSPG4/GD2 CAR-NK cells, Fludarabine, Cyclophosphamide - Unresectable Melanoma, Metastatic Cutaneous Melanoma
Phase 1 / Phase 2RecruitingBeijing Biotech362026-03-022026-06-04
Dual-Target CLDN18.2/HER2 CAR-NK Cells for Advanced Esophageal Adenocarcinoma
EBNK-1822H2 dual-target CLDN18.2/HER2 CAR-NK cells, Fludarabine, Cyclophosphamide - Recurrent or Metastatic Esophageal Adenocarcinoma, Biomarker-selected CLDN18.2-positive and/or HER2-positive Disease
Phase 1 / Phase 2RecruitingBeijing Biotech362026-03-022026-06-03
TIL Therapy in cSCC and MCC
LN-145, Cyclophosphamide, Fludarabine - Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma
Phase 2RecruitingKaram Khaddour, MD, MS142026-02-102026-02-13
Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Autologous Anti-CD83 CAR T-cells, Biospecimen Collection, Chest Radiography - Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
Phase 1RecruitingRoswell Park Cancer Institute262026-02-022026-09-24
Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)
Dual-target CAR-NK cells (EB-DT-CAR-NK), Lymphodepleting chemotherapy, Supportive care - Breast Cancer (Locally Advanced or Metastatic), HER2-positive Breast Cancer
Phase 1 / Phase 2RecruitingBeijing Biotech602026-02-022026-03-20

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Conditions studied

Leukemia, Myeloid, Acute (230)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (214)  ·  Leukemia (204)  ·  Myelodysplastic Syndromes (188)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (175)  ·  Lymphoma (148)  ·  Lymphoma, Non-Hodgkin (143)  ·  Multiple Myeloma (131)  ·  Hodgkin Disease (123)  ·  Lymphoma, Follicular (111)  ·  Lymphoma, Mantle-Cell (108)  ·  Lymphoma, Large B-Cell, Diffuse (96)  ·  Lymphoma, B-Cell, Marginal Zone (89)  ·  Myeloproliferative Disorders (87)  ·  Congenital Abnormalities (86)

Sponsors

M.D. Anderson Cancer Center (112)  ·  Fred Hutchinson Cancer Center (84)  ·  National Cancer Institute (NCI) (74)  ·  Masonic Cancer Center, University of Minnesota (52)  ·  St. Jude Children's Research Hospital (19)  ·  City of Hope Medical Center (18)  ·  H. Lee Moffitt Cancer Center and Research Institute (14)  ·  Baylor College of Medicine (13)  ·  Alliance for Clinical Trials in Oncology (12)  ·  Case Comprehensive Cancer Center (12)  ·  UNC Lineberger Comprehensive Cancer Center (12)  ·  University of California, San Francisco (12)  ·  Chinese PLA General Hospital (11)  ·  Memorial Sloan Kettering Cancer Center (11)  ·  Roswell Park Cancer Institute (11)

Countries

United States (689)  ·  China (37)  ·  Italy (29)  ·  Germany (28)  ·  Canada (23)  ·  Denmark (20)  ·  United Kingdom (20)  ·  France (17)  ·  Australia (11)  ·  Austria (10)  ·  Russia (10)  ·  Belgium (9)  ·  Sweden (8)  ·  South Korea (7)  ·  Spain (7)

Top investigators

Brenda Sandmaier (16)  ·  Steven A Rosenberg, M.D. (16)  ·  Claudio G. Brunstein, MD, PhD (7)  ·  James N Kochenderfer, M.D. (7)  ·  Steven A. Rosenberg, MD, PhD (7)  ·  Mary Horowitz, MD (6)  ·  Richard E. Champlin, MD (6)  ·  Brandon Triplett, MD (5)  ·  David Maloney (5)  ·  George Georges (5)  ·  Steven Rosenberg, M.D. (5)  ·  Uday Popat, MD (5)  ·  Weidong Han, Ph.D (5)  ·  Asad Bashey, MD, PhD (4)

Results publications

PMID 32499241, PMID 34515338, PMID 22555974, PMID 21403127, PMID 22430088, PMID 35007144, PMID 36240296, PMID 16344317, PMID 18997171, PMID 19179301, PMID 20661232, PMID 23547837, PMID 23861247, PMID 24719405, PMID 24916506, PMID 25432172, PMID 27507877, PMID 28380315, PMID 30573690, PMID 32747469, PMID 34385708, PMID 34889384, PMID 12171484, PMID 12393429, PMID 14550808, PMID 15112270, PMID 15314059, PMID 15352988, PMID 15466923, PMID 16051743, PMID 16484584, PMID 16785067, PMID 17020988, PMID 17283363, PMID 17283364, PMID 17296974, PMID 17579184, PMID 17640728, PMID 17658394, PMID 18418404, PMID 18698002, PMID 19015393, PMID 19016733, PMID 19167681, PMID 19197729, PMID 19270751, PMID 19304957, PMID 19528536, PMID 19594547, PMID 19638218

NIH funding

P30CA015704 (53), P01CA018029 (19), U10CA031946 (12), P01CA078902 (9), P30CA033572 (9), U24CA076518 (7), P01CA044991 (6), P30CA006973 (6), P30CA016672 (6), P30CA043703 (6), U01HL069294 (6), P01CA015396 (4), U10CA180821 (4), U10CA180886 (4), P01HL036444 (3)