13 completed, 9 unknown, 2 terminated. 24 Phase 3, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 24 | Completed 13, Unknown 9, Terminated 2 |
| Phase 2 | 10 | Completed 8, Unknown 2 |
Follow Oxidative Stress: new trials by email Literature Review of Oxidative Stress trials Research Report on Oxidative Stress
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Melatonin in Pediatric Hemodialysis Patients Melatonin, Placebo - Hemodialysis Complication, Oxidative Stress | Phase 3 | Unknown | Ain Shams University | 40 | 2022-12-01 | 2023-01-31 |
| Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery Intravenous Ascorbate, Normal Saline 10 mL Injection - Oxidative Stress, Ischemia-reperfusion Injury | Phase 3 | Unknown | University of Malaya | 34 | 2022-09-25 | 2022-11-25 |
| Vitamin D, Oxidative Stress and Inflammation in Hemodialysis Cholecalciferol - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Ain Shams University | 25 | 2022-05-15 | 2023-02-06 |
| Garcinia Mangostana L Rind and Solanum Lycopersicum Fructus Trial to Prevent Exercise-induced Oxidative Stress Garcinia-mangostana-L-rind and Solanum-Lycopersicum-Fructus mixture-extract, Placebo Control - Exertion; Excess, Oxidative Stress | Phase 2 / Phase 3 | Unknown | Universitas Negeri Semarang | 30 | 2020-07-15 | 2019-07-30 |
| Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia Omega 3, Nigella Sativa Oil, Hydroxyurea - Iron Overload, Oxidative Stress | Phase 2 / Phase 3 | Completed | Beni-Suef University | 350 | 2019-11-01 | 2021-01-27 |
| Impact of Estrogen + Estradiol Receptor Alpha Modulator Therapy on Oxidative Stress in Post-menopausal Women With and Without Sleep Apnea Duavive (0.45 estrogens mg and 20 mg bazedoxifene) - Sleep Apnea, Post Menopausal | Phase 3 | Unknown | Laval University | 36 | 2019-11-01 | 2022-04-08 |
| Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics Pyridoxine, Cobalamin, Placebo Oral Tablet - Schizophrenia, Drug Induced Movement Disorder, Unspecified | Phase 2 / Phase 3 | Unknown | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 45 | 2019-09-03 | 2019-12-18 |
| Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia Alpha-lipoic acid, Placebo Oral Tablet - Schizophrenia, Oxidative Stress | Phase 2 / Phase 3 | Completed | Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara | 48 | 2019-09-01 | 2022-08-29 |
| Clinical Trial of Antioxidant Therapy in Patients With Septic Shock Melatonin 5 mg, Vitamin C 1 GM Oral Tablet, Vitamin E 400 UNT - Oxidative Stress, Septic Shock | Phase 3 | Unknown | American British Cowdray Medical Center | 131 | 2018-07-23 | 2021-08-10 |
| Safety and Efficacy of Nabilone in Alzheimer's Disease Nabilone, Placebo - Alzheimer Disease, Agitation | Phase 2 / Phase 3 | Completed | Sunnybrook Health Sciences Centre | 38 | 2015-01-01 | 2020-06-25 |
| Influence of a Short Term Supplementation With Ubiquinol on Diverse Aspects Related to the Physical Activity Ubiquinol, Control - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Universidad de Granada | 100 | 2013-04-01 | 2013-09-12 |
| Effect of Alpha-lipoic Acid on Biochemical Markers and Important Outcomes in Patients Admitted to Intensive Care Units alpha-lipoic acid, placebo - Oxidative Stress, Inflammation | Phase 3 | Unknown | najmeh hejazi | 80 | 2013-02-01 | 2013-06-28 |
| N-acetylcysteine for Tobacco Smoking N-acetylcysteine - Tobacco Smoking, Oxidative Stress | Phase 3 | Unknown | Universidade Estadual de Londrina | 32 | 2013-02-01 | 2014-04-28 |
| Effect of Mother DHA Supplementation on Premature Newborn. DHA, control - Oxidative Stress | Phase 2 / Phase 3 | Completed | Universidad de Granada | 40 | 2012-01-01 | 2015-12-02 |
| Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress Pterostilbene 50 mg twice daily, Placebo, Grape Extract - Hyperlipidemia, Blood Pressure | Phase 2 / Phase 3 | Completed | University of Mississippi Medical Center | 80 | 2010-12-01 | 2018-01-10 |
| Obesity, Inflammation and Oxidative Stress Vitamin C (ascorbic acid), Placebo tablet - C-reactive Protein, Inflammation | Phase 3 | Completed | University of California, Berkeley | 512 | 2010-01-01 | 2015-12-02 |
| Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3 valsartan (ARB), ramipril (ACE inhibitor), Placebo - Oxidative Stress, Endothelial Dysfunction | Phase 3 | Terminated | Vanderbilt University | 78 | 2010-01-01 | 2016-02-15 |
| Safety of Various Mode of Delivery of Iron Supplement on Iron Toxicity Markers in Preschool Children Iron Supplementation - Iron Overload, Oxidative Stress | Phase 3 | Unknown | Annamalai University | 240 | 2009-10-01 | 2009-09-21 |
| Effect of Selenium on Serum Adiponectin, Homocystein and Malnutrition-inflammation Complex Syndrome in Hemodialysis Patients Selenium Supplement, placebo - Oxidative Stress, Inflammation | Phase 3 | Completed | maryam ekramzadeh | 80 | 2009-04-01 | 2012-02-14 |
| Effect of Mother DHA Supplementation on Term Newborn. DHA Supplementation, Control (milk without DHA) - Oxidative Stress, Inflammation | Phase 2 / Phase 3 | Completed | Universidad de Granada | 120 | 2008-04-01 | 2013-09-20 |
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Inflammation (10) · Iron Overload (2) · Malnutrition (2) · Schizophrenia (2) · Alzheimer Disease (1) · Hyperlipidemias (1) · Hypoalbuminemia (1) · Infertility, Male (1) · Metabolic Diseases (1) · Motor Activity (1) · Obesity (1) · Pain (1) · Protein-Energy Malnutrition (1) · Psychomotor Agitation (1) · Renal Insufficiency, Chronic (1)
Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (12) · Nutritional and Metabolic Diseases (9) · Nutrition Disorders (5) · Behavior (3) · Mental Disorders (3) · Metabolic Diseases (3) · Body Weight (2) · Deficiency Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Iron Metabolism Disorders (2) · Male Urogenital Diseases (2) · Malnutrition (2) · Nervous System Diseases (2)
Ascorbic Acid (3) · Docosahexaenoic Acids (3) · Acetylcysteine (2) · Melatonin (2) · Milk (2) · Thioctic Acid (2) · Angiotensin-Converting Enzyme Inhibitors (1) · Cholecalciferol (1) · Deferoxamine (1) · Honey (1) · Hydroxyurea (1) · Injections (1) · Nigella sativa oil (1) · Pentoxifylline (1) · Pterocarpus marsupium (1)
Universidad de Granada (3) · Ain Shams University (2) · Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara (2) · American British Cowdray Medical Center (1) · Annamalai University (1) · Beni-Suef University (1) · Isfahan University of Medical Sciences (1) · Laval University (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · Repromed (1) · Sunnybrook Health Sciences Centre (1) · Universidade Estadual de Londrina (1) · Universitas Negeri Semarang (1) · University of California, Berkeley (1) · University of Malaya (1)
United States (4) · Brazil (3) · Egypt (3) · Iran (3) · Spain (3) · Canada (2) · Australia (1) · India (1) · Indonesia (1) · Italy (1) · Malaysia (1) · Mexico (1) · Saudi Arabia (1)
Julio J Ochoa, Ph.D. (2) · Lia LO Sanders, MD, PhD (2) · Ahmed F Mahmoud Hussein, MS.c (1) · Alfredo Aisa Alvarez, MD (1) · Arezu Dezfuli, MD (1) · Daniel M Riche, Pharm.D. (1) · Farid Zand, MD (1) · Gianfranco Pagano, MD (1) · Gladys Block, PhD (1) · Jennie Jing, MS (1) · Jonathan Himmelfarb, MD (1) · Julio J Ochoa (1) · Kamyar Kalantar-Zadeh, MD MPH PhD (1)
PMID 22787172, PMID 23431291, PMID 25057276, PMID 25988553, PMID 30753761, PMID 31182351, PMID 31322567, PMID 31547752, PMID 32390133, PMID 34532852, PMID 36584248, PMID 37174730, PMID 37532985, PMID 37916745, PMID 41565787
2005 (1), R01HL065193 (1), R21DK078012 (1)