22 completed. 22 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 22 | Completed 22 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow Otitis: new trials by email Literature Review of Otitis trials Research Report on Otitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing. Manukamed - Manukapli 100% sterile honey wound dressing - Premium medical grade 16+ Leptospermum Scoparium New Zealand honey - Otitis Media, Suppurative, Tympanic Membrane Perforation | Phase 2 / Phase 3 | Completed | Fakultas Kedokteran Universitas Indonesia | 64 | 2021-06-13 | 2022-11-04 |
| A Study to Assess the Safety, Tolerability and Efficacy of OP0201 as an Adjunct Treatment for Acute Otitis Media in Infants and Children Aged 6 to 24 Months OP0201, Placebo, Amoxicillin-clavulanate - Acute Otitis Media | Phase 2 | Completed | Novus Therapeutics, Inc | 103 | 2019-02-21 | 2020-08-18 |
| Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT) Tymbion Iontophoresis and Tube Delivery System (TDS) - Barotrauma;Ear, OME - Otitis Media With Effusion | Phase 2 | Completed | Tusker Medical | 30 | 2017-06-27 | 2020-01-18 |
| Dose Ranging Study of OTO-201 in AOMT 6 mg ciprofloxacin, 12 mg ciprofloxacin, Sham - Acute Otitis Media, AOMT | Phase 2 | Completed | Otonomy, Inc. | 95 | 2016-02-01 | 2020-10-19 |
| OTO-201 for the Treatment of Otitis Externa OTO-201 (ciprofloxacin) - Otitis Externa | Phase 2 | Completed | Otonomy, Inc. | 75 | 2015-07-01 | 2020-10-19 |
| Open-Label Study of OTO-201 for Treatment of AOMT OTO-201 - Acute Otitis Media, AOMT | Phase 2 | Completed | Otonomy, Inc. | 39 | 2015-03-01 | 2020-10-19 |
| Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution - Acute Otitis Media | Phase 2 | Completed | Currax Pharmaceuticals | 112 | 2013-11-01 | 2024-08-07 |
| Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis Media Benzocaine, Placebo - Pain, Acute Otitis Media | Phase 2 | Completed | Otic Therapy, LLC | 65 | 2013-09-01 | 2015-05-25 |
| Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis Media benzocaine, placebo - Pain, Otitis Media | Phase 2 | Completed | Arbor Pharmaceuticals, Inc. | 38 | 2012-05-01 | 2015-05-04 |
| Efficacy and Safety of Once-Daily Ciprodexa Otic Foam Compared to Twice-daily Ciprodex Ear Drops in Acute Otitis Externa Ciprodex Otic Suspension, Ciprodexa Otic Foam - Otitis Externa, Otorhinolaryngologic Diseases | Phase 2 | Completed | Otic Pharma | 100 | 2011-07-01 | 2011-11-02 |
| Effect of Simethicone on Eustachian Tube Dysfunction Simethicone, Placebo - Otitis Media | Phase 2 | Completed | University of Pittsburgh | 25 | 2011-03-01 | 2016-06-27 |
| Evaluation of the Tympanostomy Tube Delivery System tympanostomy tube - Otitis Media With Effusion, Acute Otitis Media | Phase 2 / Phase 3 | Completed | Integra LifeSciences Corporation | 53 | 2010-09-01 | 2024-08-06 |
| Safety and Efficacy of Once-Daily Dosing of FoamOtic Cipro Compared to Twice-Daily Dosing of Ciloxan Ear Drops in Patients With Acute External Otitis 0.3% Ciprofloxacin Ear Drops, FoamOtic Cipro - Otitis Externa, Otorhinolaryngologic Diseases | Phase 2 | Completed | Otic Pharma | 70 | 2010-07-01 | 2011-03-15 |
| Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis Externa 0.3% Ciprofloxacin Ear Drops, 0.3% Ciprofloxacin Foam Otic Cipro - Otitis Externa, Otorhinolaryngologic Diseases | Phase 1 / Phase 2 | Completed | Otic Pharma | 100 | 2009-05-01 | 2009-12-24 |
| Pharmacokinetics Of Azithromycin Immediate Release And Extended Release Formulation In Kids With Acute Otitis Media 60 mg/kg azithromycin ER, 30 mg/kg azithromycin IR - Acute Otitis Media | Phase 2 | Completed | Pfizer | 38 | 2008-12-01 | 2010-02-18 |
| A Phase II Study of an Otic Formulation in Treating Peri-Operative Tube Otorrhea Moxidex otic solution, Moxifloxacin otic solution, Tympanostomy tubes - Acute Otitis Media | Phase 2 | Completed | Alcon Research | 303 | 2007-11-01 | 2012-12-03 |
| Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy adenoidectomy, myringotomy, tubes insertion, A-M - Otitis Media With Effusion | Phase 2 | Completed | Aghia Sophia Children's Hospital of Athens | 52 | 2007-09-01 | 2012-01-23 |
| A Trial to Evaluate Faropenem Medoxomil in the Treatment of Acute Otitis Media Faropenem Medoxomil - Otitis Media | Phase 2 | Completed | Replidyne | 328 | 2006-01-01 | 2008-02-08 |
| Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea Pneumococcal 7 valent conjugate vaccine (Prevenar®) - Pneumonia, Meningitis | Phase 2 | Completed | Papua New Guinea Institute of Medical Research | 318 | 2005-05-01 | 2011-07-12 |
| Safety and Efficacy Study of Cefdinir Oral Suspension, in Pediatric Subjects to Treat Acute Otitis Media cefdinir - Acute Otitis Media | Phase 2 / Phase 3 | Completed | Abbott | 447 | 2002-07-01 | 2008-03-27 |
Showing 20 of 22. Sign in to see all of them.
Otitis Media (17) · Otitis Externa (4) · Ear Diseases (3) · Earache (3) · Otitis Media with Effusion (3) · Otorhinolaryngologic Diseases (3) · Pain (2) · Communicable Diseases (1) · Meningitis (1) · Otitis Media, Suppurative (1) · Pneumonia (1) · Tympanic Membrane Perforation (1)
Ear Diseases (19) · Otorhinolaryngologic Diseases (19) · Pathological Conditions, Signs and Symptoms (6) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Pain (3) · Infections (2) · Disease Attributes (1) · Lung Diseases (1) · Nervous System Diseases (1) · Neuroinflammatory Diseases (1) · Otitis Media (1) · Pathologic Processes (1) · Respiratory Tract Diseases (1)
Ciprofloxacin (5) · Benzocaine (2) · Middle Ear Ventilation (2) · Adenoidectomy (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Antipyrine (1) · Azithromycin (1) · Cefdinir (1) · Heptavalent Pneumococcal Conjugate Vaccine (1) · Pneumococcal Vaccines (1) · Simethicone (1) · faropenem medoxomil (1) · salicylhydroxamic acid (1)
Otic Pharma (3) · Otonomy, Inc. (3) · Abbott (1) · Aghia Sophia Children's Hospital of Athens (1) · Alcon Research (1) · Arbor Pharmaceuticals, Inc. (1) · Currax Pharmaceuticals (1) · Fakultas Kedokteran Universitas Indonesia (1) · Integra LifeSciences Corporation (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Institute on Deafness and Other Communication Disorders (NIDCD) (1) · Novus Therapeutics, Inc (1) · Otic Therapy, LLC (1) · Papua New Guinea Institute of Medical Research (1) · Pfizer (1)
United States (13) · Israel (5) · Costa Rica (3) · Chile (1) · Dominican Republic (1) · Greece (1) · Guatemala (1) · Indonesia (1) · Panama (1) · Papua New Guinea (1)
Carl LeBel, PhD (3) · Yehudah Roth, MD (3) · Amy Agua, MD (1) · Andrew Gould, MD (1) · Bryan Harvey, MD (1) · Charles Syms, MD (1) · David Yen, MD (1) · Deborah Lehmann, MBBS, Msc (1) · Gerald Shockey, MD (1) · Harim Priyono (1) · Ioannis M Vlastos, MD (1) · Jacob Zeiders, MD (1) · James Hendrick, MD (1) · James Peterson, MD (1)
PMID 18831749, PMID 19150378, PMID 19776196, PMID 21645573, PMID 23451070, PMID 25444821, PMID 28580433, PMID 28702291, PMID 29028802, PMID 34851411
P50AT000008 (1)